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Ibugesic Plus Tablet

20 Tablet(s) in Strip
By CIPLA LIMITED
Salt: Ibuprofen 400.0 Mg+Paracetamol / Acetaminophen 325.0 Mg
MRP ₹41.49
₹30.29 27% OFF
₹1.51/Tablet (Inclusive of all taxes)
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30 days easy return policy
✱Offer applicable on order above ₹1000

Product Summary

Ibugesic Plus Tablet is an analgesic, fever-reducing and anti-inflammatory medicine from Cipla used to treat headache, toothache, body ache, muscle or joint pain and fever. It contains ibuprofen 400 mg and paracetamol 325 mg. Both ingredients reduce chemicals involved in pain and fever, while ibuprofen also reduces inflammation.

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CIPLA LIMITED

Dose Form

TABLET

Expiry

General Information

Therapy
Analgesic/antipyretic
Composition
Ibuprofen(400.0 Mg)+Paracetamol / Acetaminophen(325.0 Mg) Ibuprofen 400.0 Mg+Paracetamol / Acetaminophen 325.0 Mg
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Ibuprofen 400.0 Mg+Paracetamol / Acetaminophen 325.0 Mg

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About Ibugesic

Ibugesic Plus Tablet is an analgesic and antipyretic medication, widely used for the short-term management of mild to moderate pain, inflammation, and fever. It contains two active ingredients: Ibuprofen (a non-steroidal anti-inflammatory drug, or NSAID) and Paracetamol (Also Known as Acetaminophen). Ibuprofen works by inhibiting the cyclooxygenase (COX) enzymes, which are essential for the production of prostaglandins, a class of chemicals in the body that cause pain, fever, and inflammation. Paracetamol enhances the pain-relieving and fever-reducing effects by acting centrally in the brain, where it blocks the generation of pain signals and regulates body temperature.

This medication is commonly used for conditions such as headaches, toothaches, muscle and joint pain, menstrual cramps, postoperative discomfort, and fever. It is especially beneficial when both pain and inflammation need to be managed simultaneously. Ibugesic Plus provides a faster onset of action and enhanced efficacy compared to either component used alone. However, its use should be limited to the lowest effective dose for the shortest possible duration to avoid adverse effects, particularly gastrointestinal irritation, liver stress, and kidney function compromise.

While Ibugesic Plus is not habit-forming, it should be used with caution in individuals with liver or kidney impairment, gastrointestinal ulcers, bleeding disorders, asthma, cardiovascular conditions, or autoimmune disorders. It is contraindicated in pregnant women (especially during the third trimester), and caution is advised in breastfeeding mothers due to the mild excretion of components into breast milk. Alcohol should be strictly avoided during treatment as it significantly increases the risk of liver toxicity and gastrointestinal bleeding. Ibugesic Plus should not be taken along with other paracetamol-containing products or NSAIDs, unless prescribed by a healthcare provider.

The tablet should be taken with or after food to reduce stomach upset. Dosing should follow your physician's guidance. Using it long-term or at high doses without medical supervision can cause serious problems such as liver failure, kidney damage, or peptic ulcer disease. It may also interact with several medications, including blood thinners (e.g., warfarin), antihypertensives, antiepileptics, antibiotics (e.g., ciprofloxacin), and immunosuppressants (e.g., tacrolimus). Always consult a doctor before starting or combining it with other medications, especially if managing chronic conditions.

Combiflam tablet, Flexon tablet, and Imol Plus tablet also contain the same composition as Ibugesic Plus tablet.

Uses

Ibugesic Plus tablet is a pain reliever. It is used to treat headaches, toothaches, body aches, muscle pain, joint pain, and fever.

Contraindications

  • If you are allergic to Ibuprofen, Paracetamol, or other Ibugesic Plus tablet ingredients,
  • If you have a history of allergic reactions due to painkillers like aspirin, etc.
  • If you are taking medicines containing Paracetamol, Ibuprofen, or other pain medicines.
  • If you have a history of ulcers or bleeding in the digestive tract.
  • If you have an active clotting disorder or disorder related to the blood supply to the brain.
  • If you are experiencing fluid loss (due to vomiting, diarrhoea, or not drinking enough fluids).
  • If you have a kidney or liver function problem.
  • If you are pregnant (last trimester), it should not be given to children under 12 years of age (<40kgs).

Side effects

  • Stomach pain
  • Diarrhoea
  • Vomiting
  • Dizziness
  • Bloating
  • Constipation
  • Headache (rare)
  • Excessive sweating
  • Skin rashes & itching

Precautions and Warnings

Alcohol

Alcohol

UNSAFE

You should avoid consuming alcohol along with this medicine. It can increase the risk of liver disease and stomach bleeding.

Pregnancy

Pregnancy

CONTRAINDICATED

Pregnant women should not consume this medicine. This medicine can hamper the growth of fetus and can also cause heart and kidney-related problems in the baby. It can delay the labour and increase the duration as both mother and baby are at a risk of bleeding disorders if consumed by pregnant women. Women who are trying to conceive and taking treatment for infertility should not take this medicine.

Breast feeding

Breastfeeding

WITH CAUTION

This medicine passes in breast milk in low concentrations and may not be harmful to the breastfed baby. It can be used for short durations and at lowest possible dose if you are breastfeeding your baby.

Driving

Driving

WITH CAUTION

You may experience dizziness, drowsiness, fatigue and visual disturbances. Thus, it is advised not to drive when you are taking this medicine and experiencing these signs.

General warnings

Other General Warnings

Talk to your doctor if
  • You are an older adult.
  • You have high blood pressure or heart, kidney or liver diseases.
  • You may experience stomach bleeding and ulcers after taking this medicine.
  • You have a history of or suffer from asthma & nasal allergy.
  • You are suffering from an immune disorder, where your immune system acts against the body tissues.
  • You have a hereditary disorder like G6PD deficiency or porphyria (blood disorders).
  • You are an alcoholic or recently had major surgery.
  • You're trying to conceive; you should discontinue this medicine.
  • If you develop skin allergies like rashes, itching, bumps, blisters, etc.

Doctor’s suggestion

Dr. Vishesh Bharucha
Dr. Vishesh Bharucha MBBS, MD Medicine ★★★★★
Use judiciously in elderly patients, as they are at a higher risk of NSAID-related gastrointestinal bleeding and kidney injury.

Directions for use

Swallow this tablet with a full glass of water. This medicine can be taken with or without meals but if you have a sensitive stomach, it is preferably taken with meals.

Storage and disposal

  • Keep this medicine out of the reach of children.
  • Store this medicine below 30°C.

Quick tips

  • Ibugesic Plus tablet is recommended for short-term use only. Do not take more than the daily prescribed dose, as it may affect the liver or cause allergic reactions.
  • You should inform your doctor if you have experienced asthma, rhinitis or hives after taking aspirin or other NSAIDs.
  • Before taking this medicine, inform your doctor if you are pregnant, planning on getting pregnant or breastfeeding. Also, inform your doctor about all your medications and medical history.
  • Ibugesic Plus tablets should be taken with food to minimize side effects such as stomach discomfort.
  • Patients with a history of stomach ulcers, kidney disease, or liver disease should avoid taking them.

Dosage

Overdose

  • Taking this medicine in high doses may result in serious liver damage, coma and even death.
  • Other symptoms are headache, nausea, vomiting, stomach pain, diarrhoea, unconsciousness, excitement, coma, dizziness, low blood pressure, fits, difficulty in breathing & weight loss.
  • If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital.

Missed a dose

Do not take a double dose if you have missed the dose. Take the next dose as soon as you remember. A minimum of 6 hour gap is recommended between 2 doses.

How Ibugesic works

This combination acts by interfering with the production of a chemical called prostaglandins which is responsible for swelling and pain. It also controls fever and promotes cartilage matrix synthesis.

Interactions

Drug interactions of Ibugesic with other medicine salt

Food interactions

Ibugesic Plus Tablet can be taken with or without food. However, it is best taken with food to reduce side effects.

Frequently asked questions

No, Ibugesic plus tablet is not addictive but it is advised not to give this medicine if anyone else has the same condition as you.
You should take Ibugesic plus as per the requirement. However, there should be a gap of a minimum 6-hour between 2 tablets of Ibugesic plus tablet. You must not take more than 3 tablets in 24 hours. Avoid using this medicine for more than 4 days on self-prescription.
Ibugesic plus tablet should be taken with or after a meal. This helps reduce the chances of stomach irritation.
No, Ibugesic Plus is not effective against colds and flu. Colds and flu are seasonal infections usually caused by a virus, and this medicine does not act against the infection-causing organism. It is used to reduce fever and relieve pain associated with the ear, nose, and throat.
Ibuprofen and paracetamol are the active ingredients in Ibugesic Plus. On the other hand, Calpol contains only paracetamol, so it is best to seek advice from a doctor on the best option for your specific needs.
Ibugesic Plus combines ibuprofen and paracetamol. Crocin, on the other hand, contains only Paracetamol. It is recommended to consult with a doctor for personalized advice on the best option.
No, do not take Ibugesic Plus Tablet with any other paracetamol-containing medicines (such as some cold and flu remedies) unless advised to do so by your doctor. Doing so can increase the risk of liver toxicity.
Yes, long-term use may lead to stomach bleeding, kidney problems, or other complications. Always use this medicine for the shortest time necessary and under the supervision of a healthcare professional.
Ibugesic Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be necessary depending on the severity of the condition. It is important to consult your doctor before using this medication if you have any kidney-related issues.
Ibugesic Plus Tablet should be used cautiously in patients with liver disease. Dose adjustment might be required, and medical supervision is recommended. The tablet is not recommended for individuals with severe or active liver disease.
Ibugesic Plus may provide pain relief within 30–60 minutes; however, it should not be taken daily for extended periods unless prescribed by a physician, as prolonged use can affect the stomach, kidneys, or liver. It is not recommended for dengue, because some painkillers may increase bleeding risk, and caution is needed after a C-section, so it should only be used if a doctor advises.
Ibugesic Plus contains ibuprofen and paracetamol, which help relieve pain and inflammation. It can be used for period cramps and some types of stomach or abdominal pain caused by inflammation, but it does not treat cough itself. Always use it as advised by your doctor and avoid taking it on an empty stomach to reduce the risk of irritation.
Ibugesic Plus contains ibuprofen and paracetamol, which are toxic to birds, dogs, and cats. These animals are highly sensitive to these medicines, and even small doses can cause serious poisoning, organ damage, or death. Never give Ibugesic Plus to pets; always consult a veterinarian for safe alternatives.
Ibugesic Plus contains ibuprofen (a painkiller and anti-inflammatory) and paracetamol (pain and fever reliever), providing stronger relief for mild to moderate pain and inflammation. Meftagesic DS contains mefenamic acid and paracetamol, and Meftal P contains mefenamic acid, mainly for menstrual or muscle pain. Crocin DS, Dolo 250, and P250 contain paracetamol alone and are effective for mild pain and fever. Ibuflamer P is similar to Ibugesic Plus, and Butacort is a steroid-based anti-inflammatory used for more severe inflammation. Ibugesic Plus is effective for general pain and inflammation, while other medicines differ in strength, target pain type, or mechanism. Always consult your doctor before use.

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