Duonase F 70Md Bottle Of 9.8Gm Nasal Spray
9.8g Nasal Spray in Bottle
Product Summary
Duonase F 70Md Nasal Spray is a combination nasal spray used to relieve moderate to severe allergic rhinitis symptoms such as sneezing, a blocked or runny nose, nasal itching and watery eyes. It contains fluticasone furoate along with a second active ingredient, which together reduce nasal swelling, redness and mucus production for more complete allergy relief.
Medically Reviewed by Dr. Nikita Toshi
Last updated on: 13 October 2026 | 1:01 PM (IST)
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Dose Form
NASAL SPRAY
Expiry
General Information
| Therapy | Anti-allergic |
| Composition | Fluticasone Furoate(27.5 Mcg)+Azelastine Hydrochloride(140.0 Mcg) Fluticasone Furoate 27.5 Mcg+Azelastine Hydrochloride 140.0 Mcg |
Fluticasone Furoate 27.5 Mcg+Azelastine Hydrochloride 140.0 Mcg
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*Offer applicable on orders above ₹1000About Duonase
Duonase F nasal spray is a nasal spray used to relieve moderate to severe allergy symptoms affecting the nose, such as sneezing, a runny or blocked nose, nasal itching, and watery eyes. It is especially helpful when symptoms are not well controlled by using a nasal antihistamine or a steroid spray alone. By targeting both allergy triggers and inflammation, it provides more complete relief from persistent allergic rhinitis.
This medicine contains two active ingredients that work in different ways. Fluticasone furoate reduces nasal swelling, redness, and mucus production, thereby alleviating congestion and improving airflow. Azelastine hydrochloride blocks the effects of histamine, a substance released during allergic reactions, thereby quickly reducing sneezing, itching, and nasal congestion.
Duonase F nasal spray is used as a nasal spray and should be taken exactly as prescribed. Regular use is important for optimal control of allergy symptoms. Proper spraying technique helps the medicine work effectively and reduces irritation inside the nose.
Some people may experience mild side effects, such as nosebleeds, headaches, or an unpleasant taste or odor. Tiredness, dizziness, or weakness may also occur. If such symptoms impair alertness, activities such as driving or operating machinery should be avoided.
This medicine should be used with caution in certain situations, such as during pregnancy or breastfeeding, or when used for an extended period. It is important to inform your doctor about other medicines you are taking and any ongoing health conditions. Regular follow-up helps ensure safe and effective use, especially with long-term treatment.
Uses
Contraindications
Side effects
- Epistaxis (nosebleed)
- Headache
- Dysgeusia (unpleasant taste), unpleasant smell
Precautions and Warnings
Alcohol
UNSAFEIt is best to avoid or limit alcohol while using Duonase F nasal spray. Alcohol may increase side effects such as drowsiness, dizziness, or weakness, which can affect alertness and coordination. Always consult your doctor before using it.
Pregnancy
WITH CAUTIONDuonase F nasal spray should be used during pregnancy only if your doctor decides that the benefit to you outweighs the possible risk to the unborn baby. There is limited information on its use in pregnant women, so always consult your doctor before using it during pregnancy.
Breastfeeding
WITH CAUTIONIt is not known whether Duonase F nasal spray passes into breast milk. This medicine should be used while breastfeeding only if your doctor feels that the benefit to the mother is greater than the possible risk to the baby. Always consult your doctor before using it during breastfeeding.
Driving
WITH CAUTIONDuonase F nasal spray usually has little effect on the ability to drive or use machines. However, some people may feel tired, dizzy, weak, or exhausted after using it. If you experience these symptoms, avoid driving or operating machinery.
Other General Warnings
- You are taking medicines like ritonavir, as using them together with Duonase F nasal spray may increase the risk of steroid-related side effects.
- You use this spray for an extended period or at higher doses than prescribed, as it may cause effects such as weight gain, facial swelling, or hormonal imbalance.
- You have liver problems; this medication may remain longer in your body and increase the risk of side effects.
- You experience unusual fatigue, weakness, or dizziness, particularly during stress, illness, or before surgery.
- A child or adolescent is using this spray for an extended period, as growth may require monitoring.
- You notice blurred vision, eye pain, or changes in vision, as these may be linked to eye conditions such as cataract or glaucoma.
- You have a history of glaucoma, cataract, or increased eye pressure.
- You are switching from oral steroids to this nasal spray because additional care may be required.
- You have tuberculosis, an untreated infection, or have recently had surgery or injury to the nose or mouth.
- You develop persistent nasal swelling, irritation, or blockage, especially with long-term use.
Directions for use
- Use Duonase F nasal spray exactly as prescribed by your doctor.
- Gently blow your nose before using the spray to clear the nostrils.
- Shake the bottle well before each use.
- Keep your head slightly tilted forward and insert the nozzle into one nostril.
- Press the pump while gently inhaling through the nose.
- Repeat in the other nostril if advised.
- Avoid spraying directly onto the nasal septum (middle part of the nose).
- Do not sniff hard after spraying; breathe normally.
- Wipe the nozzle clean after use and replace the cap.
- Use the spray regularly for best symptom control.
Storage and disposal
- Store Duonase F nasal spray below 25°C, protect it from direct sunlight.
- Keep it away from children and pets.
- Discard the unused medicine.
Quick tips
- Use the nasal spray exactly as prescribed for best symptom control.
- Shake the bottle gently before each use.
- Clear your nose gently before spraying to help the medicine work better.
- Spray as directed and avoid sniffing hard after use.
- Wipe the nozzle clean after each use and replace the cap.
- Use the spray regularly, not just when symptoms are severe.
- Avoid driving or operating machinery if you feel drowsy after using the spray.
- Do not share your nasal spray with others.
- Inform your doctor if symptoms do not improve or if you experience nasal irritation.
Dosage
Overdose
Missed a dose
How Duonase works
- Fluticasone furoate: Reduces inflammation in the nose. It helps reduce swelling, redness, and mucus production, thereby relieving nasal congestion, sneezing, and a blocked or runny nose caused by allergies.
- Azelastine hydrochloride: Works by blocking the action of histamine, a chemical released during allergic reactions. This helps quickly relieve symptoms like sneezing, itching, a runny nose, and nasal irritation.
Interactions
Interactions with other medicines
- Using Duonase F nasal spray with medicines like ritonavir or cobicistat can greatly increase steroid levels in the body and may cause side effects such as weight gain, facial swelling, or hormone imbalance.
- Strong CYP3A4 inhibitors (such as ketoconazole) may slightly increase steroid exposure, so caution is advised when used together.
- Some medicines like erythromycin usually cause little or no meaningful interaction, but monitoring may still be needed.
- Using this nasal spray with sedative medicines or drugs that act on the brain may increase drowsiness.
- Drinking alcohol while using this nasal spray may enhance sleepiness or reduce alertness.
Food interactions
- There are no known food interactions with this nasal spray.
Frequently asked questions
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References
- Central Drugs Standard Control Organization (CDSCO). Drugs: Approved Drugs / Vaccines / r-DNA / Blood Products [Internet]. Government of India; [cited 2025 Dec 30].
- Mylan Pharmaceuticals Ltd. Azelastine hydrochloride/Fluticasone propionate 137 micrograms/50 micrograms per actuation nasal spray, suspension: Summary of Product Characteristics [Internet]. UK: Datapharm Ltd.; last updated 13 Jun 2025 [cited 2025 Dec 30].
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