Duolin Metered-Dose Inhaler
200md Metered Dose Inhaler in Box
Product Summary
Duolin Inhaler is a dual bronchodilator from Cipla used to treat bronchospasm associated with chronic obstructive pulmonary disease (COPD). It combines ipratropium 20 mcg and levosalbutamol 50 mcg, which relax airway muscles through complementary actions, widening the airways affected by bronchospasm.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 11:52 AM (IST)
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Dose Form
METERED-DOSE INHALER
Expiry
General Information
| Therapy | Anti-asthmatic, drugs for chronic obstructive pulmonary disease |
| Composition | Ipratropium(20.0 Mcg)+Levosalbutamol / Levalbuterol(50.0 Mcg) Ipratropium 20.0 Mcg+Levosalbutamol / Levalbuterol 50.0 Mcg |
Ipratropium 20.0 Mcg+Levosalbutamol / Levalbuterol 50.0 Mcg
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*Offer applicable on orders above ₹1000About Duolin
Duolin inhaler is used to treat difficulty in breathing, coughing and whistling sounds while breathing which are the symptoms of chronic obstructive pulmonary disease (COPD). It contains a combination of ipratropium and levosalbutamol as its active ingredients.
COPD is a disorder where your lung is damaged, making the passage of air in the lungs difficult. This medicine blocks the effect of substances that produces tightening of air tubes in the lungs and relaxes them.
A patient who has diabetes, glaucoma, prostate or heart problems should cautiously use this medicine. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines, supplements or herbs you take and all the conditions or diseases you suffer from or suffered before starting this medicine.
Refer to the direction of use information leaflet provided along with the Duolin inhaler before starting the treatment. Combimist L inhaler also contains a combination of ipratropium and levosalbutamol.
Uses
Contraindications
- If you are allergic to ipratropium or levosalbutamol or any other ingredients of Duolin inhaler
- If you are allergic to atropine or its derivatives
- If you have any problems with your heart
- If you are below 12 years of age (as there is no information on safety)
Side effects
- Headache
- Dizziness
- Cough
- Runny nose
- Nausea
- Vomiting
- Stomach pain
- Indigestion
- Constipation
- Dry mouth
- Sore throat
- Muscle pain or cramps
Precautions and Warnings
Alcohol
WITH CAUTIONAlcohol intake along with the use of this medicine can make you more dizzy or drowsy, thus you should avoid consuming alcohol while taking this medicine.
Pregnancy
WITH CAUTIONThere is limited information about the effects of this medicine in human pregnancy. However, your doctor may give you this medicine only if it is really needed and the advantage overweighs the risk. Please consult a doctor before using any medicine.
Breastfeeding
WITH CAUTIONIt is unknown if the components of this medicine pass into breast milk. Hence, you should not breastfeed while taking this medicine. You should consult your doctor before using this medicine during breastfeeding.
Driving
WITH CAUTIONDuolin inhaler may cause dizziness and blurring of vision, you should avoid driving if you do not feel well or are unable to be alert.
Other General Warnings
- You are suffering from any heart problems.
- You have problems with your liver or kidney.
- You have diabetes.
- You have glaucoma.
- You have high blood pressure.
- You had or have fits.
- You have an overactive thyroid gland.
- You have difficulty passing urine due to bladder problems or an enlarged prostate (mostly in men).
- You are suffering from a condition called cystic fibrosis. It increases the chances of getting stomach disturbances if you use Duolin with it.
- The chances of side effects increase significantly in the elderly population, so elderly patients should be cautious while using this medicine.
- Duolin inhaler is not recommended for use in children less than 12 years old.
Directions for use
- Use Duolin inhaler exactly as directed by your doctor. Check with your doctor or pharmacist if you are not sure.
- Read the instructions on the label or leaflet before use.
- Shake the inhaler.
- You should not take more puffs than that told by your doctor.
Storage and disposal
- Store Duolin inhaler below 25°C in a clean and dry place, protected from moisture, sunlight and heat.
- Keep the medicine away from children and pets.
Quick tips
- Duolin inhaler is used to treat the signs and symptoms of chronic obstructive pulmonary disease (COPD), such as wheezing, coughing and difficulty breathing.
- Duolin inhaler should always be used as described by your doctor. Do not swallow this medicine, use inhaler in a proper manner.
- Clean the inhaler after every use as per the instructions mentioned.
- It is recommended to rinse your mouth with water after inhalation of this medicine.
- You may develop oral fungal infection and an increase in wheezing after using this medicine
- Do not stop taking Budecort without consulting your doctor, even if you feel relieved after taking a few doses.
- Antifungal medicines such as Ketoconazole and Itraconazole should not be taken along with Duolin inhaler.
Dosage
Overdose
Missed a dose
How Duolin works
- COPD is a common lung problem that produces damage to the lungs over the period. This condition produces symptoms like coughing with mucous for a long time and eventually leading to breathing difficulties.
- Duolin inhaler works by the anticholinergic effect of Ipratropium and the bronchodilator effect of Salbutamol.
- Few chemical substances (Acetylcholine) released in the body are responsible for the tightness of breathing tubes.
- Ipratropium blocks the effect of this substance and decreases the tone of breathing tubes, thus making breathing easier.
- Salbutamol acts mainly on smaller lung tubes and dilates them by relaxing the muscles.
Interactions
Interactions with other medicines
- Concomitant use of Duolin inhaler along with medicines used to treat psychiatric illness (Amitriptyline, selegiline, etc.) or medicines used to treat asthma (Albuterol, Epinephrine) should be avoided as it may alter the effects of this medicine.
- Concomitant use of this medicine with beta-blockers like Propranolol, Labetalol, etc. (used to treat high blood pressure and heart problems), may decrease the effectiveness of Duolin inhaler.
- Concomitant use of this medicine with water pills like Furosemide, Hydrochlorothiazide may decrease the potassium level in the body which leads to heart rhythm abnormalities. Your doctor may advise the monitoring of blood potassium levels.
- Other medicines like Digoxin (used to treat heart problems), Xanthine preparations like Theophylline (used in asthma) and should be used cautiously.
Food interactions
Frequently asked questions
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References
- Duolin Respules [Internet]. CiplaMed. 2021 [cited 28 February 2022]
- CDSCO [Internet]. Cdscoonline.gov.in. 2021 [cited 28 February 2022]
- Home [Internet]. Breathefree. 2021 [cited 28 February 2022]
- ScienceDirect. Ipratropium bromide. Accessed January 1, 2025.
- Gupta MK, Singh M. Evidence based review on levosalbutamol. Indian J Pediatr. 2007 Feb. Accessed January 1, 2025.
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 123600, Levalbuterol. Retrieved January 1, 2025
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