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Zifi Xp 500mg Inj

10ml Injection
MRP 69.00*
Inclusive of all taxes
Out of Stock
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Check more medicines with composition
Ceftriaxone + Tazobactam
Therapeutic classification

Medical Description

Zifi Xp 500mg Inj contains a combination of Ceftriaxone and Tazobactam which belongs to the class of cephalosporin and penicillin antibiotics respectively.
    Side effects
    Precautions and Warnings
    Mode of Action
    Directions for Use
    Storage and disposal

Uses of Zifi Xp 500mg Inj

It is mainly used before surgeries to prevent infection which may arise post-surgery like vaginal or abdominal surgeries to remove uterus, surgery to remove gall bladder stone or for jaundice, etc.

Contraindications of Zifi Xp 500mg Inj

  • If you are allergic to Ceftriaxone and Tazobactam and any of the ingredient of this medicine
  • If you are allergic to Cephalosporins, Penicillins, Monobactams and Carbapenems
  • Should not be given to premature babies
  • If a newborn has jaundice or is on calcium injection treatment
  • If a newborn is suffering from increased bilirubin (liver enzyme) in blood

Side effects of Zifi Xp 500mg Inj

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Fever
  • Loose stools
  • Flushing
  • Rash and severe skin allergies (Allergic dermatitis)
  • Bleeding disorder (coagulopathy)
  • Itching and pain at the injection site
  • Increased liver enzymes
  • Decrease in white blood cells and red blood cells
  • Increased number of eosinophils (Eosinophilia)
  • Increased creatinine levels in blood

Precautions and Warnings of Zifi Xp 500mg Inj



Can I take Zifi Xp 500mg Inj during pregnancy?
  • The effect of this medicine on the fetus is not clearly known, it must be used only if prescribed by your doctor
  • Consult your doctor if you are pregnant, think you are pregnant or planning a baby
  • Your doctor will give you this medicine after assessing the benefits over risks

Breast Feeding

Can I take Zifi Xp 500mg Inj while breastfeeding?
  • This medicine passes in human milk in low amounts
  • The baby should be monitored for antibiotic-related side effects like diarrhoea or fungal infection of mouth
  • Your doctor will decide if the medicine should be discontinued when you are breastfeeding, only after assessing the benefit over risks


Can I drive if I have consumed Zifi Xp 500mg Inj?
You may feel dizzy after taking this injection, thus be cautious or avoid driving after taking this injection.


Can I consume alcohol with Zifi Xp 500mg Inj?
No information is available on interactions of this medicine when taken with alcohol. However, alcohol may worsen the side effect like dizziness. It is advisable to avoid alcohol if you have taken this injection

Other General Warnings

Talk to your doctor if
  • You have a history of allergy after taking the antibiotic
  • You have developed diarrhea after taking this medicine, immediately stop the medicine and inform your doctor
  • You have serious liver and kidney disease
  • You are suffering from gall bladder disease
  • You are suffering from anaemia
  • You are suffering from disease of bowel inflammation (Colitis)

Mode of Action of Zifi Xp 500mg Inj

How Does It Work?

  • Zifi Xp 500mg Inj acts by killing the bacteria responsible for infections.
  • However, bacteria make an enzyme (beta-lactamases) which can destroy Ceftriaxone
  • Tazobactam inactivates this enzyme and hence helps Ceftriaxone to function optimally

Directions for Use of Zifi Xp 500mg Inj

  • This medicine will be given in the hospital by your doctor or nurse as an injection
  • Do not self inject this medicine

Interactions of Zifi Xp 500mg Inj

Interactions with other medicines

  • There is limited information available on the interaction of this combination with other drugs. However, as this medicine contains Ceftriaxone and Tazobactam any interactions seen with these two compo...
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  • This injection should never be given along with Ringer's or Hartmann's solution
  • This medicine alters the action of oral contraceptives. Thus it is advisable to use alternative contraceptive measures like condoms when you are taking this medicine
  • This injection should never be given through the IV line through which calcium-containing solutions are given

Storage and disposal of Zifi Xp 500mg Inj

  • Store it below 25°C protected from light
  • Keep it out of the reach of children
  • Any unused portion should not be stored and should be discarded properly

Dosage of Zifi Xp 500mg Inj


  • Your doctor or nurse will give this injection, therefore chances of overdose are rare
  • However, if you experience nausea, vomiting, diarrhoea and stomach upset immediately after taking this injection, inform your doctor or reach out to your nearest hospital as soon as possible

Missed a Dose

  • You will be monitored by your doctor or nurse on when the medicine should be given to you
  • It is unlikely that the dose will be missed
  • However, if you think your doctor or nurse might have missed a dose, inform them
  • It is advisable not to miss any dose of antibiotics as it can result in failure of therapy

Content Details


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: For how long do I need to take this Zifi Xp 500mg Inj?

A: You are supposed to complete the prescribed duration of antibiotics by your doctor. Otherwise, there is a possibility of reoccurrence of the infection.
Last Updated on: 31 Jul 2020 | 07:00 PM (IST)
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