Infection of the brain
Respiratory tract infections (Pneumonia and COPD)
Ear infections
Abdominal infections
Infection of urinary tract
Bone and joint infection
Skin and soft tissue infections
Gonorrhoea and syphilis (sexually transmitted disease in both male and female genital organs)
Infection of the lining of the heart and heart valve
Infection caused by tick bite
Infection of the surgical site before operation

Contraindications of Xone 125 MG

If you are allergic to Ceftriaxone or any other ingredients of this medicine
If you are allergic to a class of medicines known as cephalosporin
If you are allergic to medicines like penicillins, monobactams and carbapenems
Do not give this injection to premature babies
If a newborn is suffering from jaundice or is on calcium injection treatment
If a newborn is suffering from increased bilirubin in blood
Ceftriaxone solution containing lidocaine should not be given as an injection

Side effects of Xone 125 MG

Increased number of eosinophils (Eosinophilia)
Decreased number of leucocytes (Leucopenia)
Diarrhea, loose stools
Increased liver enzymes
Rash
Fungal infections
Decrease in white blood cells (Granulocytopenia)
Decreased red blood cells (Anaemia)
Bleeding disorder like coagulopathy (a condition in which the ablity of blood to form clots is decreased)
Headache
Dizziness
Nausea
Vomiting
Itching at injection site
Pain at the injection site
Fever
Increased creatinine levels in blood

Precautions and Warnings of Xone 125 MG

Pregnancy

Can I take Xone 125mg Inj during pregnancy?

The medicine can be used in pregnant women and during the first trimester only if necessary
Tell your doctor if you are pregnant, think you are pregnant or plaining a baby. Your doctor will give you this medicine after assessing the benefits over risks

Breast Feeding

Can I take Xone 125mg Inj while breastfeeding?

This medicine passes in human milk in low amounts and has no effects on the breastfed baby
However, the baby should be monitored for side effects like diarrhoea or fungal infection of mouth
Your doctor will decide if the medicine should be discontinued

Driving

Can I drive if I have consumed Xone 125mg Inj?

You may feel dizzy after taking this injection, thus be cautious/avoid driving after taking this injection.

Alcohol

Can I consume alcohol with Xone 125mg Inj?

No information is available on interactions of this medicine when taken with alcohol. However, alcohol may worsen the side effect like dizziness. It is advised to avoid alcohol if you have taken this injection.

Other General Warnings

Talk to your doctor if

You have liver diseases
You have kidney diseases or kidney stones
You are suffering from gallstones
You are suffering from anaemia (reduces red blood cells)
You are suffering from bowel inflammation
You have stomach disease or problems like diarrhea after taking antibiotics
You have taken any medicine containing calcium recently
If you are planning to get a blood test, it may intefere with the results

Mode of Action of Xone 125 MG

How Does It Work?

It works by stopping the formation of cell wall of the bacteria and thus killing the bacteria which causes infection.

Directions for Use of Xone 125 MG

This medicine will be given in hospital by your doctor or nurse as an injection
Do not self inject this medicine

Interactions of Xone 125 MG

Interactions with other medicines

Calcium containing diluents like ringer lactate should not be used for reconstitution
Medicines known as oral anticoagulants (blood thinners) can increase the risk of bleeding
Medicines known as aminoglycosides (antibiotics) increase the risk of kidney damage when given with this medicine
Medicine such as local anesthetics which are known to cause methemoglobinemia (abnormal amount of methemoglobin - a type of haemoglobin)

Storage and disposal of Xone 125 MG

Store below 30°C
Protect if from light
Keep it out of the reach of children
Any unused portion should not be stored and should be discarded properly

Dosage of Xone 125 MG

Overdose

This injection will be given by your doctor or nurse, therefore it is less likely you will receive more of this medicine
However if you experience dizziness, fever, chills and stomach upset immediately after taking this injection, inform your doctor as soon as possible

Missed a Dose

You will be monitored by your doctor or nurse as to when the medicine should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed ...

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Can I stop taking Xone 125mg Inj if I feel better after taking few injections?

A: No, you should always take the full course of antibiotics,as failing that may decrease the effectiveness of treatment and will increase the resistance of bacteria. Always inform your doctor before you stop the treatment.

Q: I am allergic to Cefuroxime, can I take Xone 125mg Inj?

A: No, you should not take this medicine if you have allergy to cefuroxime. You should also never take other medicines from the same class of antibiotics like cephalexin, cefadroxil & cefazolin etc.

Q: What other disease conditions should I discuss with my doctor before taking Xone 125mg Inj?

A: You should discuss with your doctor if you are on any other medication. If you have any stomach, kidney or liver disease. If you are pregnant or breastfeeding.

Q: Can I take Xone 125mg Inj injection at home or on my own?

No, it should only be taken if prescribed by a doctor under medical supervision.

References

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Product Details

Brand

XONE

Country of Origin

India

Expires on or After

15/08/2022

Manufacturer Details

Last Updated on: 24 Feb 2022 | 06:47 PM (IST)

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.

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