Valgan 450mg Strip Of 4 Tablets
4 Tablet(s) in StripMRP ₹1527.23
₹1114.88
27% OFF
Made by
CIPLA LIMITED
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Valganciclovir(450.0 Mg) |
| Uses | Viral infection of retina |
| Therapy | Antiviral |
| Side effects | Fungal infection of the mouth (oral candidiasis), lung infection, anaemia, decreased appetite, headache, cough, diarrhoea, nausea, vomiting, abdominal pain, fatigue. |
Assurance
available
Regulated
Medical Description
Valgan tablet is an antiviral medication that contains the active ingredient valganciclovir. It is primarily used for the treatment and prevention of cytomegalovirus (CMV) infections, particularly in individuals with compromised immune systems. It belongs to a class of antiviral agents that work by inhibiting viral replication. Once ingested, valganciclovir is converted into ganciclovir, its active form, which then interferes with the DNA synthesis of the CMV virus, preventing it from multiplying and causing further infection.
Valgan tablet is used to treat CMV retinitis, a viral infection of the retina that can lead to blindness, in adult patients with acquired immunodeficiency syndrome (AIDS). It is used for both the induction and maintenance phases of therapy to manage this condition. It is also used to prevent CMV disease in individuals who have received a solid organ transplant. This preventive use is specifically for CMV-negative recipients who have received an organ from a CMV-positive donor, reducing the risk of a new infection.
The Valgan tablet works by preventing cytomegalovirus (CMV) from replicating. Once you take the tablet, your body turns the main ingredient, valganciclovir, into another substance called ganciclovir. This ganciclovir then gets activated inside the cells that are infected with the virus. It acts like a decoy, tricking the virus's machinery, called viral DNA polymerase, into using it instead of the correct building blocks. This completely stops the virus from building new DNA, which means it can't multiply or spread to other healthy cells. By doing this, Valgan helps stop the CMV infection from spreading.
Valgan tablet is administered orally and should be taken as directed by a physician. It is important to swallow the tablet whole with water and not to crush, break, or chew it. The medication can be taken with or without food, though taking it with meals may enhance its absorption. Adherence to a regular dosing schedule is crucial for optimal treatment outcomes. Patients should also be aware of potential side effects, such as low blood cell counts, which may require regular monitoring by a healthcare professional.
Uses
Contraindications
- If you have hypersensitivity to the active substance, ganciclovir, or any other ingredients of Valgan tablet.
- If you are breast-feeding.
Side effects
- Fungal infection of the mouth (oral candidiasis)
- Lung infection
- Anaemia
- Low neutrophil count
- Decreased appetite
- Headache
- Cough
- Diarrhoea
- Nausea
- Vomiting
- Abdominal pain
- Fatigue
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have low white blood cells, low red blood cells, and low platelets. Valgan tablet may cause cancer, harm developing babies, and affect sperm production.
- You have trouble with fertility. Using Valgan tablet can stop the production of sperm, which can lead to infertility. These effects can go away if you use lower doses, but they may be permanent with higher doses.
- You should use effective contraception during treatment if you are of childbearing age.
- You must strictly adhere to dosage recommendations to avoid overdose.
- You have impaired kidney function, so you need to adjust the dosage of Valgan tablet. Since Valgan tablet is removed from your body by the kidneys, it's important that your kidneys work well for it to be cleared properly.
Directions for Use
- Take Valgan tablet as directed by your physician.
- Swallow it whole with a glass of water.
- It can be taken with or without food.
- Do not break, crush or chew Valgan tablet.
- It is essential to take it regularly and at a fixed time.
- Do not exceed that dose more than that recommended.
Storage and disposal
- Store Valgan tablet at 25°C in a location away from moisture and heat.
- Ensure it is kept out of the sight and reach of children and pets.
Quick Tips
- Take Valgan tablet as a whole, do not break or crush it.
- It can be taken with or without food for better absorption.
- Follow your doctor's prescribed dose and schedule strictly.
- Do not stop taking the medicine abruptly without consulting your physician.
- Inform your doctor about all other medications you are taking to avoid interactions.
- Regularly visit your doctor for blood tests to monitor cell counts.
- Avoid breastfeeding while on this medication.
- Use effective contraception during treatment to prevent pregnancy.
- Be cautious when driving or operating machinery, as it may cause dizziness or confusion.
- If you miss a dose, take it as soon as you remember unless it's almost time for the next dose. Do not double the dose.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Zidovudine and Valgan tablet can both lead to lower blood cell counts, which may cause conditions like neutropenia (low white blood cells) and anaemia (low red blood cells). Some patients might not be able to take these medications together at their full strength without experiencing side effects. Consult your doctor and inform him/her about all the medications you are taking.
- If you are taking probenecid along with Valgan tablet, your healthcare provider should check for signs of toxicity, they will look for any harmful effects from the concomitant use of Valgan tablet and probenecid.
- For those taking Mycophenolate Mofetil, special care is needed if you have kidney issues, as the levels of this medication and its byproducts may rise, potentially leading to more side effects.
- Patients should be observed closely for signs of toxicity from the use of didanosine, which can also occur alongside Valgan tablet treatment.
Interactions with food items
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:VALGAN
Manufacturer Name:CIPLA LIMITED
Address:Cipla Ltd, Midc Patalganga,M.S-410220, India
Country of Origin:India
Vendor Details
Fulfillment Information: Valgan 450 MG Tablet (4) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Fda.gov. 2020. VALCYTE (valganciclovir hydrochloride tablets) [Cited 19 March 2025]
- Valganciclovir 450 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. [Cited 19 March 2025]
- Valganciclovir 450 mg Film-coated Tablets -PIL-Electronic Medicines Compendium (EMC). Electronic Medicines Compendium (eMC) [Internet]. Medicines.org.uk. 2019. [cited 2025 Mar 19].
- Valganciclovir 450 mg film-coated - Patient Information Leaflet (PIL) - (emc) | 11333 [Internet]. Medicines.org.uk. 2020 [cited 2025 Mar 19].
- Mondal D. Valganciclovir☆. Reference Module in Biomedical Sciences. 2016;[cited 2025 Mar 19].
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