Tolfen Capsule
10 Capsule(s) in StripMRP ₹165.23
₹135.49
18% OFF
Made by
MICRO LABS
Dosage
CAPSULE
Expiry
Product Summary
| Salt Content | Polmacoxib(2.0 Mg) |
| Uses | Osteoarthritis |
| Therapy | Drugs for osteoarthritis |
| Side effects | Nausea, Headache, Upset stomach |
Assurance
available
Regulated
Medical Description
Tolfen capsule is a medicine that works as a pain reliever and reduces inflammation. It contains polmacoxib as the main active ingredient. It targets two specific processes in the body: it tries to lower pain and inflammation by blocking the enzyme COX-2, and it also affects carbonic anhydrase (CA). By addressing both areas, it aims to minimise heart-related side effects while also being beneficial in reducing arthritis pain.
Take as directed by your doctor. It is taken orally and may be taken with or without food, as a whole, with sufficient amount of water. Side effects may include nausea, headache and upset stomach.
Uses
- Tolfen capsule is used in the treatment of osteoarthritis affecting the knee and hip joints.
Contraindications
- If you are allergic to polmacoxib, ibuprofen, aspirin, any other medicines of the NSAID group or any other ingredients of Tolfen capsule.
- If you have experienced bleeding from the stomach, have stomach ulcers or bleeding from the stomach or gut.
- If you have an increased bleeding tendency.
- If you suffer from severe heart, kidney or liver failure.
- If you are pregnant (last 3 months).
Side effects
- Nausea
- Headache
- Upset stomach
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
- You have stomach-related problems like bleeding from the stomach and ulcers (ulcerative colitis, Crohn's disease) or bleeding disorders.
- You have a history of allergic problems, asthma, etc.
- You have heart-related problems and diabetes.
- You have a serious disease of the kidney or liver.
- You suffer from autoimmune disorders like systemic lupus erythematosus (risk of aseptic meningitis) and mixed connective tissue disorders.
- You are pregnant or are planning to get pregnant.
- Use Tolfen capsule with caution in the case of children and the elderly.
Directions for Use
- Take Tolfen capsule as directed by your doctor.
- It is taken orally, with or without food, as a whole, with sufficient amount of water.
Storage and disposal
- Store Tolfen capsule below 25°C, in a cool and dry place.
- Keep out of the reach of children and pets.
Dosage
Overdose
Missed a Dose
Mode of Action
How Does It Work?
Interactions
Interactions with other medicines
- Interaction with ketoconazole or erythromycin: When using Tolfen capsule together with ketoconazole or erythromycin, it might be necessary to use a lower dose than usual.
- Interaction with ACE inhibitors or angiotensin II receptor blockers: Tolfen capsule can lessen the effect of ACE inhibitors or angiotensin II receptor blockers, which are used to lower blood pressure.
- Interaction with diuretics: Some patients may find that Tolfen capsule reduces the effectiveness of furosemide and thiazide diuretics, which help remove extra fluid from the body by affecting kidney function.
- Interaction with aspirin: Using Tolfen capsule along with aspirin may lead to more stomach problems, like ulcers, compared to when Tolfen capsule is used alone.
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Manufacturer Details
Brand:TOLFEN
Manufacturer Name:MICRO LABS
Address:Hetero Labs Limited (Unit II) - Village: Kalyanpur, Chakkan Road, Tehsil Baddi, Dist, Solan, Himanchal pradesh, 173205
Country of Origin:India
Vendor Details
Fulfillment Information: Tolfen 2 MG Capsule (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Easwaran R, Mistry UK, Bhole M, Peethambaran K, Easwaran R, Mistry UK, et al. Polmacoxib: A Review of the Newer Non-steroidal Anti-inflammatory Drug in Osteoarthritis. Cureus [Internet]. 2024 Apr 17;16(4). [Cited 20 March 2025]
- Cho YS, Bae KS, Choi SC, Cho JM, Lim HS. Population Pharmacokinetic and Pharmacodynamic Analysis of Polmacoxib in Healthy Volunteers and Patients With Osteoarthritis. Clinical Therapeutics [Internet]. 2021 Dec 31;44(1):67-80.e1. [Cited 20 March 2025]
- Prabhoo DrR, Shrivastava DrN. The role of polmacoxib as a tissue-specific cox-2 inhibitor in the management of osteoarthritis: A comprehensive review. International Journal of Orthopaedics Sciences [Internet]. 2024 Jan 1;10(3):84–91. [Cited 20 March 2025]
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
