Thre Tablets

• Treats Pulmonary tuberculosis (within the lungs)
• Treats extrapulmonary tuberculosis (outside the lungs)

• Nausea
• Vomiting
• Fever
• Dark urine
• Unusual bleeding
• Jaundice
• Visual impairment
• Increased liver enzymes
• Tingling or numbness of hands and feet

Other General Warnings

• You have hepatic and renal impairments.
• You are taking oral contraceptive pills; then these tablets may tend to slow their efficacy due to the effect of Rifampin. So, make sure to use another alternative method of contraception (e.g. condoms) to reduce the chances of unwanted pregnancy.
• You are pregnant or a breastfeeding mother.
• You may also experience the presence of dark urine and yellowing of teeth after using the Thre tablets, which are prevalent symptoms. They tend to subside after the completion of the course of medicine.

• Take the Thre tablets as per the doctor’s directions.
• Swallow one pill as a whole.
• Thre tablets are generally taken empty stomach one hour before or two hours after the meal. Avoid chewing, breaking or crushing the tablets.

Overdose

Missed a Dose

Interactions with other medicines

• Thre tablets may show interactions with;
• Acetaminophen with Thre tablets may risk some individuals with Acetaminophen-induced liver toxicity.
• Carbamazepine with Thre tablets may increase the serum levels of Carbamazepine rapidly.
• Oral contraceptive pills with Thre tablets reduce oral contraceptive pills' efficacy by enzyme induction held by Rifampicin.
• Beta-blockers with Thre tablets tend to decrease their level by enzyme induction.

Interactions with food items

• Food containing histamine or tyramine (such as aged cheese, soy sauce, red wine etc.) – These food items tend to reduce the metabolism of tyramine and histamine and increase the chances of tyramine and histamine toxicity induced symptoms like headache, diarrhoea, nausea, vomiting and tachycardia. Therefore they should not be used with Thre tablets.