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Thre Tablets

4 Tablet(s) in Strip
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Thre Tablets Description

Thre tablets is an ultimate combination of the three most important active ingredients to cure tuberculosis, i.e., “Ethambutol”, “Rifampicin”, “Isoniazid”. Thre tablets are used in tuberculosis as it

prevents the multiplication of bacteria causing tuberculosis in the body. It is prescribed for adults and children more than 15 years of age. While using this combination of medicine, make sure not to skip the doses and not leave the medicine course in between. Leaving it in between will cause more harm and worsen the condition. Some common encountered side effects of Thre tablets include nausea, vomiting, rash, fever, dark coloured urine, increased sputum production. Do not delay reporting any of the side effects following consumption of Thre tablets to your doctor, as it may require treatment and medical attention. The consumption of Thre tablets with other medicines may result in drug interactions with them, so tell the doctor about all the past illnesses and the medication you have taken to treat them. Moreover, Thre tablets may cause severe hepatic symptoms, so the doctor regularly monitors the liver while keeping the patient on Thre tablets. Avoid drinking alcohol while using the tablets to ensure that you achieve the desired effects without any complications.


Product Summary

Offer Price₹26.57
You Save₹4.32 (14% on MRP)
ContainsEthambutol + Isoniazid + Rifampicin
UsesPulmonary tuberculosis, extrapulmonary tuberculosis
Side effectsNausea, vomiting, fever, dark urine, unusual bleeding, jaundice, visual impairment, increased liver enzymes, tingling or numbness of hands and feet.
Check more medicines with composition as Ethambutol + Isoniazid + Rifampicin

Uses of Thre Tablets

  • Treats Pulmonary tuberculosis (within the lungs)
  • Treats extrapulmonary tuberculosis (outside the lungs)

Contraindications of Thre Tablets

Hypersensitivity to Isoniazid Intolerance to Rifampicin Insensitivity to Ethambutol Alcoholism Gout Acute liver failure

Side effects of Thre Tablets

  • Nausea
  • Vomiting
  • Fever
  • Dark urine
  • Unusual bleeding
  • Jaundice
  • Visual impairment
  • Increased liver enzymes
  • Tingling or numbness of hands and feet

Precautions and Warnings of Thre Tablets



Can I take Thre tablets during pregnancy?
The Thre tablets are not safe to consume Thre tablets for pregnant women.

Breast Feeding

Can I take Thre tablets while breastfeeding?
It isn’t recommended for breastfeeding mothers to take Thre tablets unless it is an absolute necessity. It can be given to breastfeeding mothers along with the proper supplementation as per the doctor’s directions.


Can I drive if I have taken Thre tablets?
You must not drive if you have taken the Thre tablets. Consuming Thre tablets may be associated with side effects like dizziness and excessive sleep. So, it is not safe at all to drive unless all your senses are under your control.


Can I consume alcohol with the Thre tablets?
Consuming alcohol with Thre tablets may prove quite unsafe as it increases the risk of severe side effects like drowsiness, nausea, vomiting, confusion, thirst, increased heartbeat and low blood pressure.

Other General Warnings

Talk to your doctor if
  • You have hepatic and renal impairments.
  • You are taking oral contraceptive pills; then these tablets may tend to slow their efficacy due to the effect of Rifampin. So, make sure to use another alternative method of contraception (e.g. condom...
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  • You are pregnant or a breastfeeding mother.
  • You may also experience the presence of dark urine and yellowing of teeth after using the Thre tablets, which are prevalent symptoms. They tend to subside after the completion of the course of medicin...
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Mode of Action of Thre Tablets

How Does It Work?

Thre tablets contain Isoniazid, Rifampicin, and Ethambutol. Isoniazid works by killing the bacteria causing tuberculosis, i.e., Mycobacterium tuberculosis. Isoniazid is a drug that gets activated by b...
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Directions for Use of Thre Tablets

  • Take the Thre tablets as per the doctor’s directions.
  • Swallow one pill as a whole.
  • Thre tablets are generally taken empty stomach one hour before or two hours after the meal. Avoid chewing, breaking or crushing the tablets.

Interactions of Thre Tablets

Interactions with other medicines

  • Thre tablets may show interactions with;
  • Acetaminophen with Thre tablets may risk some individuals with Acetaminophen-induced liver toxicity.
  • Carbamazepine with Thre tablets may increase the serum levels of Carbamazepine rapidly.
  • Oral contraceptive pills with Thre tablets reduce oral contraceptive pills' efficacy by enzyme induction held by Rifampicin.
  • Beta-blockers with Thre tablets tend to decrease their level by enzyme induction.

Interactions with food items

  • Food containing histamine or tyramine (such as aged cheese, soy sauce, red wine etc.) – These food items tend to reduce the metabolism of tyramine and histamine and increase the chances of tyramine an...
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Storage and disposal of Thre Tablets

Keep the Thre tablets in a cool and dry place. Ensure to keep the medicine away from moisture and sunlight. Keep the medicine at a place where children and pets can’t reach easily. Discard the unused ...
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Dosage of Thre Tablets


If you suspect an overdose, seek emergency help as the overdose may be associated with many symptoms like nausea, vomiting, headache, pruritus, lethargy and even unconsciousness.

Missed a Dose

Take the dose as soon as you remember it in case of a missed dose. If it is the time for the next dose, then proceed with the fresh dosage schedule and skip that dose that has been missed. Don’t doubl...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Which is the best time to take Thre tablets?

A: The best time is to take it is on an empty stomach, one hour before or two hours after the meal. Make sure to consult your doctor first.

Q: Can Thre tablets cause dark colouration of the urine?

A: Yes, the use of Thre tablets is associated with the dark colouration of the urine. Some more symptoms may appear after the consumption of Thre tablets, like discolouration of the sweat, urine, saliva and tears. However, these symptoms do subside after adequately completing of the medicine course.

Q: Do Thre tablets have any role in birth control?

A: Thre tablets have not shown such interactions with OCPs or oral contraceptive pills. However, the treatment regime includes Rifampin which lowers the efficacy of oral contraceptive pills. Therefore, it is always advised to use an alternative method of contraception (like condoms) for better prevention.

Q: Can I stop taking Thre tablets if I feel well?

A: No, you must not stop taking Thre tablets even if you are feeling well. This may cause the symptoms to worsen and can also lead to drug-resistant TB, which means the medicines you took earlier will no longer be working for your tuberculosis.

Q: Is TB or tuberculosis curable?

A: Yes TB or tuberculosis is curable. It may take 6-8 months for the treatment along with proper DOTS therapy prescribed by your doctor or DOTS workers provided by the government agency.
Product Details
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Last Updated on: 04 Jun 2022 | 05:30 PM (IST)

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