Rifa I6 Forte Tab
By CONCEPT PHARMACEUTICALS LTD
10 Tablet(s) in Strip
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Rifa I6 Forte Tablets are used in the treatment of tuberculosis or TB infection. It is made of three active ingredients, isoniazid, rifampicin, and pyrazinamide. All three are anti-tuberculosis (anti-TB) medications. They all work in various ways to kill the bacteria and lower the infection. Doctors usually prescribe to take Rifa I6 Forte Tablet for at least a few months. TB bacteria can die very slowly; hence the treatment for it can be so long. The treatment duration depends on various aspects, such as the severity of infection in the patient. The doctors will assess and decide on the medications and treatment plan. It is essential not to stop using this medicine in the middle of the treatment, even if you feel better. Or else, the infection might return, and the TB bacteria may develop resistance to the medicine....
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|Contains||Isoniazid(300.0 Mg),Rifampicin(600.0 Mg),Pyrazinamide(10.0 Mg)|
|Side effects||Dizziness, stomach upset, nausea, vomiting, drowsiness, itching, fever, jaundice, loss of appetite, salivation, excess sputum, blurred vision, joint swelling, joint pain, gout.|
Check more medicines with composition as Isoniazid(300.0 Mg) + Rifampicin(600.0 Mg) + Pyrazinamide(10.0 Mg)
Uses of Rifa I6 Forte Tab
- As per CDSCO, Rifa I6 Forte Tablet is used for,
- Treatment of tuberculosis infection(kills the bacteria).
Contraindications of Rifa I6 Forte Tab
- If you have a past history of allergic reactions to any of the components of Rifa I6 Forte Tablet.
- If you have a history of visual disorders like optic neuritis, Rifa I 6 Forte Tablet can worsen the condition.
- If you have been diagnosed with gout or have increased uric acid levels in the body.
- If you have a sudden or severe liver failure.
- If you have peripheral neuropathy (pain in extremities caused by the damage of the nerves). Rifa I6 Forte Tablet reduces the levels of vitamin B6 in the body, which will worsen this condition.
Side effects of Rifa I6 Forte Tab
- Joint pains
- Burred or loss of vision
- Skin rash
- Nausea or vomiting
- Change in the colour of urine
- Weight loss
- Bleeding or bruising
Precautions and Warnings of Rifa I6 Forte Tab
Can I take the Rifa I6 Forte Tablet during pregnancy?
If you are pregnant and are diagnosed with tuberculosis infection, take the medications in the exact way prescribed by the doctor. You may worry about your child’s health, but not taking anti-TB medicines can cause even more severe infection and sometimes death. Rifa I6 Forte Tablet medicine may reach the baby, but studies have not shown any development problems.
Can I take the Rifa I6 Forte Tablet while breastfeeding?
It is important to breastfeed the baby, even if you are taking Rifa I6 Forte Tablet. Continue using vitamin B6 tablet supplements. Some amount of Rifa I6 Forte Tablet may pass into the breast milk, but it can be too little to cause any harm. Please consult your doctor.
Can I drive if I have taken the Rifa I6 Forte Tablet?
No, Rifa I6 Forte Tablet may cause symptoms such as dizziness or blurred vision. Do not drive if you are noticing any such side effects.
Can I consume alcohol with the Rifa I6 Forte Tablet?
No, try not to consume alcohol with Rifa I6 Forte Tablet. It can interfere with the effects of this medicine and cause dizziness and drowsiness, affecting your ability to drive.
Other General Warnings
Talk to your doctor if
- You have already had tuberculosis before and used the Rifa I6 Forte Tablet before for the treatment of TB, inform your doctor.
- You want to stop using Rifa I6 Forte Tablet if you are feeling better. Do not stop in the middle and finish the entire course of this treatment. Otherwise, TB infection may come back, and it will become harder to fight the bacteria....
- You have tingling sensations in the extremities, nerve pain or damage. It may be due to vitamin B6 deficiency, which can cause inflammation of nerve cells.
- You are on oral birth control pills. Rifa I6 Forte medicine reduces their effectiveness, so use other contraceptive methods like condoms, diaphragms, etc.
- You take certain antacids regularly. Try not to take antacids immediately after taking Rifa I6 Forte Tablet.
Mode of Action of Rifa I6 Forte Tab
How Does It Work?
Rifa I6 Forte Tablet has three active components, isoniazid, rifampicin, and pyrazinamide. Isoniazid prevents the TB bacteria from forming a protective layer that helps it survive. Rifampicin deactivates RNA polymerase, an enzyme in the TB bacteria. It is required for the process of making proteins, which the bacteria uses for multiplying. Pyrazinamide slows the growth of TB bacteria by preventing the production of specific proteins....
Directions for Use of Rifa I6 Forte Tab
- Take Rifa I6 Forte Tablet exactly as advised by the doctor for the entire prescribed duration.
- Try to take them 1 to 2 hours before consuming food.
- Do not exceed the prescribed dosage of Rifa I6 Forte Tablet.
- Take Rifa I6 Forte Tablet as a whole with a glass of water. Do not try to break or chew it.
- Do not take Rifa I6 Forte Tablet if the package has been already opened.
- Do not suddenly stop taking this tablet, as the infection can return.
- Do not take Rifa I6 Forte Tablet with other medications without informing your doctor.
Interactions of Rifa I6 Forte Tab
Interactions with other medicines
- If you are currently using phenytoin (anti-seizure medicine) or disulfiram (for alcohol addiction), Rifa I6 Forte Tablet will increase the level of these medicines in the blood and cause adverse effects....
- Rifampicin (a component of this tablet) is contraindicated in HIV-positive patients using certain types of antivirals like protease inhibitors. It can lower the effect of HIV medication.
- If you are using oral contraceptives or birth control, blood thinners (warfarin), certain diabetic medicines (sulfonylureas), and methadone, Rifa I6 Forte Tablet can lower the level of these medicines in the blood....
Interactions with food items
- Try to take Rifa I6 Forte Tablet on an empty stomach, or else the food can interfere with the effectiveness of this medicine. If you experience severe stomach upset, you can take these tablets after a meal....
- Try to avoid caffeine, sodium, spicy condiments, processed sugar and flour. Foods containing saturated and trans fats worsen the TB symptoms of diarrhoea, abdominal cramps, and fatigue.
- Tobacco should be avoided during this disease treatment.
- Avoid food with high tyramine content such as aged cheese, cured meat, soy sauce, beer, red wine, etc.
Storage and disposal of Rifa I6 Forte Tab
Store Rifa I6 Forte Tablet in dry conditions and at room temperature. Keep them away from wet surfaces, direct sunlight, and humidity. Keep Rifa I6 Forte Tablet away from the reach of children and pets. Dispose of this medicine's packaging after use. Check the expiration date before taking them. Do not use Rifa I6 Forte tablets if they are past the expiration date....
Dosage of Rifa I6 Forte Tab
Overdose of Rifa I6 Forte Tablet causes symptoms like stomach pain, nausea, vomiting, itching, slurred speech, increased heart rate, lack of consciousness, urinary retention, and dark-coloured skin, urine, saliva, or stools. If you experience symptoms of Rifa I6 Forte Tablet overdose, contact your doctor and seek medical treatment....
Missed a Dose
It is important not to miss even a single dose of the Rifa I6 Forte Tablet. However, if you miss a scheduled dose and it is the same day, take it. If you remember the next day, skip the missed dose and take Rifa I6 Forte Tablet from that day. Do not take two doses on the same day to compensate. If you miss more doses consecutively, immediately consult your doctor....
Frequently Asked Questions (FAQs)
Q: Can I use antacid medicines while using the Rifa I6 Forte Tablet?
A: It is generally not recommended to use both of these medicines at the same time. Do not take antacids within 2 hours of taking Rifa I6 Forte Tablet. Consult your doctor if you are having persistent stomach upset and have other stomach problems.
Q: Can I stop using the Rifa I6 Forte Tablet if I am feeling better and I don't have symptoms anymore?
A: No, do not stop using Rifa I6 Forte Tablet any time in the middle of the treatment, even if you think you are feeling better. Tuberculosis bacteria die very slowly, and it takes a long time to completely eliminate them. If you stop the medicines in the middle, the bacteria will multiply again and may gain resistance to the current treatment. This causes reinfection and makes it even harder to kill the bacteria.
Q: Can I wear contact lenses while using the Rifa I6 Forte Tablet?
A: No, it is not advisable to wear contact lenses while on this treatment. Rifa I6 Forte Tablet can change the colour of eyes, urine, etc., to orange. This colour change is not harmful. However, it can permanently change the colour of your contact lenses.
- Adverse events [Internet]. Centers for Disease Control and Prevention. Centers for Disease Control and Prevention; 2016 [cited 2022 Feb 22]. Available from:
- G; CKCYWWS. Clinical research in the treatment of tuberculosis: Current status and future prospects [Internet]. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. U.S. National Library of Medicine; [cited 2022 Feb 22]. Available from
- Torres NMC, Rodríguez JJQ, Andrade PSP, Arriaga MB, Netto EM. Factors predictive of the success of tuberculosis treatment: A systematic review with meta-analysis [Internet]. PLOS ONE. Public Library of Science; [cited 2022 feb 22]. Available from:
- Tuberculosis [Internet]. National Institute of Allergy and Infectious Diseases. U.S. Department of Health and Human Services; [cited 2022 Feb 22]. Available from:
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 2022 Feb 22]. Available from:
RIFA I 6 FORTE
Expires on or After
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