Rifa I6 Forte Tablets
10 Tablet(s) in StripWe do not sell this product
Made by
CONCEPT PHARMACEUTICALS LTD
Dosage
TABLET
Expiry
Product Summary
| Salt Content | Isoniazid(300.0 Mg)+Rifampicin(600.0 Mg)+Pyrazinamide(10.0 Mg) |
| Uses | Tuberculosis infection |
| Therapy | Anti-tubercular |
| Side effects | Dizziness, stomach upset, nausea, vomiting, drowsiness, itching, fever, jaundice, loss of appetite, salivation, excess sputum, blurred vision, joint swelling, joint pain, gout. |
Assurance
available
Regulated
Medical Description
Rifa I6 Forte Tablets are used in the treatment of tuberculosis or TB infection. It is made of three active ingredients, isoniazid, rifampicin, and pyrazinamide. All three are anti-tuberculosis (anti-TB) medications. They all work in various ways to kill the bacteria and lower the infection.
Doctors usually prescribe to take Rifa I6 Forte Tablet for at least a few months. TB bacteria can die very slowly; hence the treatment for it can be so long. The treatment duration depends on various aspects, such as the severity of infection in the patient. The doctors will assess and decide on the medications and treatment plan. It is essential not to stop using this medicine in the middle of the treatment, even if you feel better. Or else, the infection might return, and the TB bacteria may develop resistance to the medicine.
Uses
- As per CDSCO, Rifa I6 Forte Tablet is used for,
- Treatment of tuberculosis infection(kills the bacteria).
Contraindications
- If you have a past history of allergic reactions to any of the components of Rifa I6 Forte Tablet.
- If you have a history of visual disorders like optic neuritis, Rifa I 6 Forte Tablet can worsen the condition.
- If you have been diagnosed with gout or have increased uric acid levels in the body.
- If you have a sudden or severe liver failure.
- If you have peripheral neuropathy (pain in extremities caused by the damage of the nerves). Rifa I6 Forte Tablet reduces the levels of vitamin B6 in the body, which will worsen this condition.
Side effects
- Chills
- Joint pains
- Burred or loss of vision
- Skin rash
- Nausea or vomiting
- Change in the colour of urine
- Weight loss
- Bleeding or bruising
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have already had tuberculosis before and used the Rifa I6 Forte Tablet before for the treatment of TB, inform your doctor.
- You want to stop using Rifa I6 Forte Tablet if you are feeling better. Do not stop in the middle and finish the entire course of this treatment. Otherwise, TB infection may come back, and it will become harder to fight the bacteria.
- You have tingling sensations in the extremities, nerve pain or damage. It may be due to vitamin B6 deficiency, which can cause inflammation of nerve cells.
- You are on oral birth control pills. Rifa I6 Forte medicine reduces their effectiveness, so use other contraceptive methods like condoms, diaphragms, etc.
- You take certain antacids regularly. Try not to take antacids immediately after taking Rifa I6 Forte Tablet.
Directions for Use
- Take Rifa I6 Forte Tablet exactly as advised by the doctor for the entire prescribed duration.
- Try to take them 1 to 2 hours before consuming food.
- Do not exceed the prescribed dosage of Rifa I6 Forte Tablet.
- Take Rifa I6 Forte Tablet as a whole with a glass of water. Do not try to break or chew it.
- Do not take Rifa I6 Forte Tablet if the package has been already opened.
- Do not suddenly stop taking this tablet, as the infection can return.
- Do not take Rifa I6 Forte Tablet with other medications without informing your doctor.
Storage and disposal
Store Rifa I6 Forte Tablet in dry conditions and at room temperature. Keep them away from wet surfaces, direct sunlight, and humidity. Keep Rifa I6 Forte Tablet away from the reach of children and pets.
Dispose of this medicine's packaging after use. Check the expiration date before taking them. Do not use Rifa I6 Forte tablets if they are past the expiration date.
Dosage
Overdose
Overdose of Rifa I6 Forte Tablet causes symptoms like stomach pain, nausea, vomiting, itching, slurred speech, increased heart rate, lack of consciousness, urinary retention, and dark-coloured skin, urine, saliva, or stools. If you experience symptoms of Rifa I6 Forte Tablet overdose, contact your doctor and seek medical treatment.
Missed a Dose
It is important not to miss even a single dose of the Rifa I6 Forte Tablet. However, if you miss a scheduled dose and it is the same day, take it. If you remember the next day, skip the missed dose and take Rifa I6 Forte Tablet from that day. Do not take two doses on the same day to compensate. If you miss more doses consecutively, immediately consult your doctor.
Mode of Action
How Does It Work?
Rifa I6 Forte Tablet has three active components, isoniazid, rifampicin, and pyrazinamide. Isoniazid prevents the TB bacteria from forming a protective layer that helps it survive. Rifampicin deactivates RNA polymerase, an enzyme in the TB bacteria. It is required for the process of making proteins, which the bacteria uses for multiplying.
Pyrazinamide slows the growth of TB bacteria by preventing the production of specific proteins.
Interactions
Interactions with other medicines
- If you are currently using phenytoin (anti-seizure medicine) or disulfiram (for alcohol addiction), Rifa I6 Forte Tablet will increase the level of these medicines in the blood and cause adverse effects.
- Rifampicin (a component of this tablet) is contraindicated in HIV-positive patients using certain types of antivirals like protease inhibitors. It can lower the effect of HIV medication.
- If you are using oral contraceptives or birth control, blood thinners (warfarin), certain diabetic medicines (sulfonylureas), and methadone, Rifa I6 Forte Tablet can lower the level of these medicines in the blood.
Interactions with food items
- Try to take Rifa I6 Forte Tablet on an empty stomach, or else the food can interfere with the effectiveness of this medicine. If you experience severe stomach upset, you can take these tablets after a meal.
- Try to avoid caffeine, sodium, spicy condiments, processed sugar and flour. Foods containing saturated and trans fats worsen the TB symptoms of diarrhoea, abdominal cramps, and fatigue.
- Tobacco should be avoided during this disease treatment.
- Avoid food with high tyramine content such as aged cheese, cured meat, soy sauce, beer, red wine, etc.
Frequently Asked Questions (FAQs)
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Manufacturer Details
Brand:RIFA I 6 FORTE
Vendor Details
Fulfillment Information: Rifa I6 Forte Tablets will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
References:
- Adverse events [Internet]. Centers for Disease Control and Prevention. Centers for Disease Control and Prevention; 2016 [cited 2022 Feb 22]. Available from:
- G; CKCYWWS. Clinical research in the treatment of tuberculosis: Current status and future prospects [Internet]. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. U.S. National Library of Medicine; [cited 2022 Feb 22]. Available from
- Torres NMC, Rodríguez JJQ, Andrade PSP, Arriaga MB, Netto EM. Factors predictive of the success of tuberculosis treatment: A systematic review with meta-analysis [Internet]. PLOS ONE. Public Library of Science; [cited 2022 feb 22]. Available from:
- Tuberculosis [Internet]. National Institute of Allergy and Infectious Diseases. U.S. Department of Health and Human Services; [cited 2022 Feb 22]. Available from:
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 2022 Feb 22]. Available from:
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
