Parafena Tab contains combination of aceclofenac and paracetamol.
Precautions and Warnings
Mode of Action
Directions for Use
Storage and disposal
Uses of Parafena Tab
Treatment of pain & swelling of joints (osteoarthritis & rheumatoid arthritis)
Treatment of pain & inflammation of spinal cord (ankylosing spondylitis)
Treatment of pain and swelling in ear, nose or throat, lower back pain
Treatment of lower abdominal pain, uterine cramps and pain related to periods (Gynecological pain)
Treatment of toothache
Contraindications of Parafena Tab
If you are allergic to aceclofenac, paracetamol or any of the ingredients of this medicine
If you have a history of asthma, skin rashes, swelling & nasal congestion after taking aspirin, ibuprofen or other NSAIDs
If you have a history of frequent stomach ulcers or bleeding
If you have severe heart problems like heart failure, high blood pressure
If you have severe liver or kidney disorder
If you are pregnant especially in third trimester of pregnancy
Side effects of Parafena Tab
Nausea, vomiting (with or without blood)
Elevated levels of liver enzymes & creatinine
Precautions and Warnings of Parafena Tab
Can I take Parafena Tab during pregnancy?
It is unsafe to take this medicine during pregnancy; hence it should not be taken by a pregnant women
Taking this medicine in pregnancy can cause defects in the baby's heart or even delay of labour.
Can I take Parafena Tab while breastfeeding?
It is advised not to use this medicine if you are breastfeeding.
Can I drive if I have consumed Parafena Tab?
It is advised not to drive or use machines when you have taken this medicine as it may cause dizziness.
Can I consume alcohol with Parafena Tab?
It is advisable to avoid the consumption of alcohol during the treatment as it may worsen your liver problems. Contact your doctor or pharmacist for further information.
Other General Warnings
Talk to your doctor if
You have kidney problems or liver problems
You are an elderly patient or taking diuretics or have kidney disorders; this medicine can increase the risk of kidney failure. Your doctor may ask you to do renal function tests for the same.
You are suffering from gastrointestinal problems like bleeding, ulcers in the intestine (perforation) or Crohn's disease,
You have asthma as this medicine can worsen the same
You have SLE
You are an alcoholic, as concomitant use of this medicine can damage the liver
You have disorders related to blood clotting
You have skin rashes & lesions after taking this medicine
Mode of Action of Parafena Tab
How Does It Work?
This combination acts by interfering with the production of a chemical called prostaglandins, which is responsible for swelling and pain.
It also controls fever and promotes cartilage matrix synthesis....
Directions for Use of Parafena Tab
This medicine should be consumed as a whole with a sufficient amount of water and can be taken with food or after food.
Interactions of Parafena Tab
Interactions with other medicines
No drug interaction reports are available for this combination. However, as this medicine contains aceclofenac & paracetamol, any interactions seen with these two components when taken alone may occur with this combination...
Other medicines containing paracetamol, as there is increased risk of liver damage
If you are taking medicines used to treat high blood pressure, this medicine can interfere with their effect
Medicines like diuretic can lead to kidney damage when taken along with this medicine
Medicines used to treat heart failure (Cardiac glycosides)
This medicine can increase the levels of lithium and it's side effects
Medicines used to treat certain type of cancer like methotrexate
Medicines used to modify immune response during organ transplant like ciclosporin & tacrolimus can result in kidney damage if taken with this medicine
Increase the risk of stomach ulcers or bleeding when taken with steroids
There is risk of bleeding if you are taking medicines to thin the blood like warfarin, coumarin
Increased risk of fits if you are taking this medicine with antibiotics like levofloxacin, ciprofloxacin (Quinolone )
Medicines used to treat HIV infections like zidovudine
If you are taking medicines for treating diabetes, be cautious about symptoms of low glucose levels like sweating, anxiety, fast heartbeat, hunger pangs
Medicines used to treat fits, seizures & depression-like phenobarbital, carbamazepine, phenytoin
Medicine used to treat gout-like probenecid
Medicine used to treat tuberculosis (TB), rifampicin
Medicine used for pain relief like aspirin
Medicine used to treat mental problems like depression & the blues (St. John's Wort)
Interactions with food items
No information is available on interactions of this medicine when taken with food, consult your doctor or pharmacist for further details.
Storage and disposal of Parafena Tab
Store it in a cool and dry place and away from light.
Dosage of Parafena Tab
Taking Parafena Tab in high doses may result in severe liver damage
Other symptoms headache, nausea, vomiting, stomach pain, diarrhoea, unconsciousness, excitation, coma, dizziness, low blood pressure, fits, difficulty in breathing & weight loss
If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you missed any dose of medicine, take it as soon as you remember
If it's time for your next dose, then skip the missed dose and continue with your regular dose schedule
Do not take a double dose of medicine to compensate for the missed one.
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