Lumerax Dry Syrup 60ml
By IPCA LABORATORIES
60ml Dry Syrup in Bottle
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Lumerax Dry Syrup 60ml Description
Lumerax dry syrup belongs to a category called antimalarials. It contains artemether and lumefantrine and is used to treat acute uncomplicated malaria caused by Plasmodium falciparum, which infects t
he red blood cells.
Uses of Lumerax Dry Syrup 60ml
- To treat acute uncomplicated malaria caused by Plasmodium falciparum; used in infants weighing above 5 kgs, children and adults.
Contraindications of Lumerax Dry Syrup 60ml
- Hypersensitivity to either of the active components or any of the syrup's additional constituents
- Severe malaria
- CYP2D6 enzyme-dependent medicines such as metoprolol, imipramine, clomipramine, and amitriptyline
- On electrocardiograms, family history of sudden death or genetic QTc interval lengthening
- Medications that cause the QT interval on the ECG to extend
- Heart arrhythmias, low blood pressure, and heart failure in the past
- Electrolyte abnormalities such as hypokalaemia or hypomagnesemia
- When taking rifampin, carbamazepine, phenytoin, or St. John's Wort
Side effects of Lumerax Dry Syrup 60ml
- Joint or muscle pain
- Loss of appetite
Precautions and Warnings of Lumerax Dry Syrup 60ml
Is the Lumerax dry syrup safe for use during pregnancy?
This combination of medicines is not recommended for use, especially during the first trimester. However, if any life-threatening situation arises or other medicines do not prove to be effective, it may be advised by the doctor. It is not clear whether the medicine can cause harm to the baby or cause abortion.
Is it okay to take Lumerax dry syrup when I'm breastfeeding?
It has been found during animal experiments that lumefantrine and artemether can enter breast milk. No such data is available for humans. It is in the patient's best interest to avoid using this syrup while breastfeeding.
Can I drive after taking the Lumerax dry syrup?
The active contents of this medicine show side effects like dizziness or fatigue. In such cases, one must avoid driving.
Can I consume alcohol after taking the Lumerax dry syrup?
There is no data available on whether or not alcohol affects the action of Lumerax dry syrup.
Other General Warnings
Talk to your doctor if
- You have a chronic condition and are taking medication for it
- You have liver or kidney issues
- You suffer from a heart disorder
- You have taken or are taking other antimalarial medications
- You have a malaria infection from both Plasmodium falciparum and Plasmodium vivax parasites
- You feel worse after taking the medicine and do not feel like eating or drinking anything
- You are taking medicines for treating HIV, birth control, allergies, any antibiotics, antidepressives, epilepsy
- You are taking St John's wort (Hypericum perforatum)
Mode of Action of Lumerax Dry Syrup 60ml
How Does It Work?
Artemether and lumefantrine are the active ingredients in Lumerax dry syrup. Artemether works by preventing the conversion of a substance called haem, which is produced when the malaria parasite breaks down haemoglobin in the bloodstream. The parasite is poisoned by this haem, thus it is transformed into harmless hemozoin. Lumefantrine obstructs the polymerisation process. Artemether and lumefantrine both have a secondary effect that stops the malarial parasite from producing genetic material to reproduce further....
Directions for Use of Lumerax Dry Syrup 60ml
- Take the Lumerax dry syrup with high-fat foods or beverages, such as milk
- Consult your doctor right away if you vomit within the first hour of taking the medicine
- Follow the doctor's instructions and finish the medication course that has been recommended
- Make certain you do not skip any doses so that the medicine can work properly
- If you feel worse after taking the syrup, see your doctor
Interactions of Lumerax Dry Syrup 60ml
Interactions with other medicines
- Artemether and Lumefantrine effect may be reduced if you take rifampin
- Due to the lack of data on its safety, other antimalarials are not recommended to be taken with it
- Taking carbamazepine, phenytoin, and St. John's wort can also lower levels of medications in Lumerax syrup
- When ketoconazole and Lumerax dry syrup are taken together, the levels of the two active ingredients may rise, raising the risk of QT prolongation in the ECG
- Antiviral medicines have the potential to increase or reduce medication concentrations in the blood, increasing the risk of QT prolongation or inadequate blood concentration
- Concurrent usage of mefloquine (antimalarial) may lower lumefantrine levels in the blood, reducing the medicine's efficacy
- Concurrent usage of hormonal contraceptives can lessen the effectiveness of this medication's actions
- Flecainide, imipramine, amitriptyline, clomipramine, and other medications that can cause QT prolongation should be avoided while taking this medication
- Quinine, an antimalarial medicine, should be used with caution because it can reduce artemether exposure
- Antibiotics, antidepressants, neuroleptics, and cardiac medications all raise the risk of QT prolongation and should be used with caution
Storage and disposal of Lumerax Dry Syrup 60ml
Temperatures of 20°C to 25°C are recommended for storage; small temperature changes are acceptable. Make sure it's out of sight and out of reach of children. After the expiration date on the blister, do not use the tablets. Do not dispose of any leftover medicine in the trash or flush it down the toilet. Inquire with your pharmacist about how to safely discard old medications....
Dosage of Lumerax Dry Syrup 60ml
If you take more than the recommended amount of this medicine and suspect an overdose, reach out to your doctor right away or go to the nearest emergency room where appropriate supportive therapy can be administered. An overdose should not be taken lightly....
Missed a Dose
If you miss a dosage, take the syrup as soon as you remember. Even if you recall, do not take the tablet if it is almost time for another dose. It is not a good idea to take an extra dose to make up for a missed one. It is likely to cause major issues. In this case, seek medical advice....
Frequently Asked Questions (FAQs)
Q: Can I take this medicine on empty stomach?
A: Artemether and lumefantrine present in this medicine are absorbed best when taken with food. This also prevents any unwanted gastric side effects that may be caused by the active ingredients.
Q: Can this medicine also help prevent malaria?
A: No, these medicines are only used for the treatment of malaria caused by a specific type of organism. It acts directly on the organism and kills them. Hence, it will not help prevent the condition.
Q: Who should not take Lumerax dry syrup?
A: Patients with severe or complicated malaria caused by P. falciparum are not prescribed this medicine. Other treatments are available in this case. Also, refer to the contraindications section for more information on who should not take this medication.
Q: What if I vomit after taking Lumerax syrup?
A: You should contact your doctor if you vomit within a hour after taking the syrup. There may be a need to change the medicine. You must also mention any other factors that may have triggered this response.
- DailyMed - COARTEM- artemether and lumefantrine tablet [Internet]. Dailymed.nlm.nih.gov. 2022 [cited 10 March 2022]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7866ec19-dfac-47d4-a53f-511a12643cbf
- Riamet 20/120mg tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 10 March 2022]. Available from: https://www.medicines.org.uk/emc/medicine/9196#MACHINEOPS
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