Lucaparib 200Mg Bottle Of 60 Tablets

• Lucaparib tablet is a PARP inhibitor used to treat certain ovarian, fallopian tube, primary peritoneal, and prostate cancers.
• It is used as maintenance treatment for recurrent ovarian, fallopian tube, or primary peritoneal cancer in adults with a BRCA mutation who have a complete or partial response to platinum-based chemotherapy.
• In prostate cancer, it is used for BRCA-mutated metastatic castration-resistant prostate cancer after androgen receptor-directed therapy.

• There are no absolute contraindications to Lucaparib tabletspecified in the approved prescribing information.
• Lucaparib tablet should not be used by patients who have a known hypersensitivity to rucaparib or any of the tablet's inactive ingredients.

• Nausea
• Tiredness or weakness (fatigue/asthenia)
• Anaemia (low red blood cell/haemoglobin count)
• Changes in liver blood tests (raised ALT/AST)
• Vomiting
• Diarrhoea
• Reduced appetite
• Low platelet count (thrombocytopenia)
• Change in taste (dysgeusia)
• Low white blood cell count (neutropenia/leukopenia)
• Raised blood creatinine
• Muscle or joint pain (in prostate cancer patients)
• Constipation

• Shortness of breath
• Dizziness
• Indigestion
• Increased sensitivity to sunlight (photosensitivity)
• Swelling of the legs or feet
• Decreased weight
• Abdominal pain
• Rash
• Tingling or numbness (peripheral neuropathy)
• Urinary tract infection
• Cough
• Headache
• Unusual bleeding

• A serious bone marrow disorder (MDS) or blood cancer (AML) may develop.
• Significant drops in blood cell counts can increase the risk of infection, bleeding, or severe anaemia.

Other General Warnings

• You have previously received chemotherapy, as this may increase your risk of bone marrow problems withLucaparib tablet.
• You notice unusual bruising, bleeding, or blood in your urine or stool, as this may signal low blood counts needing assessment.
• You develop fever, chills, or signs of infection, since low white blood cell counts can increase infection risk.
• You feel unusually breathless, tired, or weak, which may reflect anaemia or another change in your blood counts.

• Take Lucaparib tablet exactly as prescribed by your doctor.
• Tablets may be taken with or without food.
• Do not change your dose, stop treatment, or restart treatment on your own. Always consult your doctor first.

• Store Lucaparib tablettablets at room temperature.
• Keep Lucaparib tabletand all medicines out of the reach of children and pets.
• Do not use tablets that are damaged or past their expiry date.

• Take Lucaparib tablet exactly as prescribed, with or without food.
• Attend all scheduled blood tests.
• Contact your doctor promptly if you notice unusual tiredness, fever, frequent infections, easy bruising, or bleeding.
• Use effective contraception during treatment and for the duration your doctor specifies afterwards, whether you are female or male.
• Protect your skin from sunlight, as Lucaparib tabletcan increase sun sensitivity.
• Never stop or change your dose without speaking to your doctor first, even if you feel well or unwell.

Missed a Dose

Overdose

• {cb}} tablet is a PARP inhibitor that blocks PARP enzymes, which help repair DNA damage. In cancer cells with a weakened DNA-repair system, such as those with a BRCA mutation, this blockade overwhelms their repair capacity.
• As unrepaired DNA damage accumulates, the cancer cell can no longer function and ultimately dies. This makes Lucaparib tablet particularly effective against cancers associated with BRCA mutations, as these cells rely heavily on the disrupted repair pathways.

Interactions with other medicines

• Lucaparib tablet can raise blood levels of medicines broken down by liver enzymes (CYP1A2, CYP3A, CYP2C9, CYP2C19), potentially increasing side effects.
• If you take warfarin, your doctor may need to check INR more often.
• Medicines processed by the same liver enzyme pathways asLucaparib tablet, including some hormonal contraceptives, may have their levels affected during combined use.
• Always inform your doctor and pharmacist about all medications, vitamins, supplements, or herbal products you take or plan to take. They can check for interactions before and during your treatment withLucaparib tablet.

Interactions with food items