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Ketrip 25mg Tablets

10 Tablet(s) in Strip
We do not sell this product

Made by

KIVI LABS LIMITED

Dosage

TABLET

Expiry

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Product Summary

Salt Content
Amitriptyline(25.0 Mg)
Uses
Depression, neuropathic pain, and migraine
Therapy
Anti-depressant
Side effects
Constipation, urinary retention, Weight gain, Confusion, Orthostatic hypotension (sudden lowering of blood pressure on standing), Tiredness, Blurred vision, Dryness in mouth
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Ketrip is a prescription medication. It contains Amitriptyline. This medication is a tricyclic antidepressant. It is used to treat depression and manage neuropathic pain (pain that occurs due to damage to nerves) and migraine in varying doses. Depression is associated with low mood, difficulty performing daily activities, difficulty sleeping, hopelessness, and negative feelings. These changes may be associated with altered levels of many chemical messengers in the brain, such as serotonin, dopamine, and norepinephrine. Treatment may last for several months and requires regular follow-up. The medication should be taken as per the recommendations of a trained medical professional. It is not advisable to start or stop the tablet suddenly. Withdrawal symptoms may occur on abrupt discontinuation. It is recommended to take the pill at the same time daily for maximum efficacy.

Uses

  • Major Depressive Disorder
  • Neuropathic pain (pain that occurs due to damage to nerves)
  • Migraines

Contraindications

  • Avoid using this medication in case of hypersensitivity reactions to these medications/ inactive ingredients.
  • This medication should not be used in patients with a recent history of heart conditions such as irregular heart rhythm or myocardial infarction (heart attack).
  • It is contraindicated in patients with angle-closure glaucoma.
  • The tablet should be discontinued before elective surgery to decrease the risk of interaction with anaesthetic agents.
  • This medication decreases the seizure threshold and should be used cautiously in epilepsy/ seizure disorders patients.
  • It should be used with caution in adolescents and young adults less than 24 years due to a potential increase in the risk of suicidal ideation.

Side effects

  • Weight Gain
  • Constipation
  • Dry mouth
  • Dizziness
  • Headache
  • Somnolence/ Sleepiness
  • Urinary retention
  • Orthostatic hypotension (sudden lowering of blood pressure on getting up from a lying down position)
  • Dizziness

Precautions and Warnings

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Pregnancy

No, Ketrip should not be used during pregnancy as it can increase the chances of complications such as high blood pressure and affect the growing fetus. Consult your doctor, and inform them if you are pregnant or planning a pregnancy.

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Breast Feeding

This medication is generally not advised while breastfeeding, as it is secreted in breast milk and can cause harm to the infant.

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Driving

Ketrip causes increased sleepiness, and it is not advisable to drive or perform any tasks that require focus.

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Alcohol

Alcohol consumption while on this medication is contraindicated as mixing alcohol with this medication may cause increased sedation and other adverse effects.

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Other General Warnings

Talk to your doctor if
  • You are on any other medications you are. Ketrip is metabolised using a group of enzymes that affect the blood levels of many other medications if taken at the same time.
  • If you experience any sudden mood changes or suicidal ideation.

Directions for Use

  • Ketrip Tablets should be taken as prescribed by the treating physician.
  • It is recommended to take this medication on a regular schedule, i.e., at the same time every day, for optimal pharmacological effects of this medication.
  • Swallow this medication as a whole. Do not crush, chew or break this tablet.
  • Do not stop the tablet or change the dose suddenly unless advised by a doctor.
  • This medication may require 2-4 weeks for onset of action. Inform your doctor regarding other medications you may be taking to review and prevent any associated effects of any medicine interaction.

Storage and disposal

Store in a cool and dry place away from direct light and moisture. Dispose of the medication after the date of expiration. Keep the tablets away from children and pets. Do not flush the medication down the toilet. Dispose of it with biomedical waste only.

Dosage

Overdose

Amitriptyline overdose can have serious consequences. Patients may present with sedation, seizure, coma, increased heart rate, low blood pressure, dilated pupils, dry mouth, difficulty passing urine or stools, abnormal heart rhythms, dilated pupils, dry mouth, low urine output. In case of a suspected overdose, immediately rush the patient to the nearest tertiary care hospital for emergency management as it is life-threatening.

Missed a Dose

If you miss a dose of Ketrip, take the missed dose as soon as possible. If the duration missed is too long, or it is almost time for the next dose, you must not double the dose of the tablet. Instead, skip the missed dose and go back to the regular schedule.

Mode of Action

How Does It Work?

Amitriptyline is a Tricyclic antidepressant (TCA) that raises the levels of certain chemical messengers in the brain called neurotransmitters. It works by increasing the neurotransmitters serotonin and norepinephrine levels that affect mood and personality. It also causes sleepiness. In the long term, it increases the levels of BDNF (brain-derived neurotrophic factor). This reduces the symptoms of Major Depressive Disorder. The action of this medicine on serotonin and nor-epinephrine is also indicated in the management of neuropathic pain (pain that occurs due to damage to nerves) and migraine. It is important to note that Ketrip as an anti-depressant requires about 2-4 weeks of continued use for the optimal onset of action to begin.

Interactions

Interactions with other medicines

  • This medication affects the heart rhythm and should not be used in addition to other medications with the same effect, as it may result in potentially life-threatening conditions. Examples include astemizole, cisapride, etc.
  • This medication should not be used along with medications belonging to the class of monoamine oxidase inhibitors such as isocarboxazid, selegiline, etc. This can cause a dangerous increase in levels of serotonin.
  • Ketrip should not be used with any other medications known to increase serotonin levels as it may result in a potentially fatal condition known as serotonin syndrome. These include methylene blue, tramadol, linezolid, etc.
  • Ketrip should not be used with alcohol or other agents that act as depressants of the central nervous system.
  • Ketrip should not be mixed with medications belonging to the class of opioids or benzodiazepines such as alprazolam or clonazepam.

Interactions with food items

  • This medication has no specific interactions with food.

Frequently Asked Questions (FAQs)

Ketrip must be used for the entire duration as prescribed by a doctor. It is not recommended to stop taking the tablet suddenly as it can result in withdrawal symptoms.

It takes 2-4 weeks for Ketrip to properly take effect. Take this medication as directed by your treating physician. It is important to review routinely for appropriate dose adjustment. Talk to your doctor for more information.

Weight gain and increased appetite are common side effects of Ketrip. The tablet must be continued as advised. Stopping the tablet abruptly can worsen the symptoms.

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Manufacturer Details

Brand:KETRIP

Vendor Details

Fulfillment Information: Ketrip 25 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

References:

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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