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Ketrip 25mg Tablets

10 Tablet(s) in Strip
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Ketrip 25 MG Description

Ketrip is a prescription medication. It contains Amitriptyline. This medication is a tricyclic antidepressant. It is used to treat depression and manage neuropathic pain (pain that occurs due to dama

ge to nerves) and migraine in varying doses. Depression is associated with low mood, difficulty performing daily activities, difficulty sleeping, hopelessness, and negative feelings. These changes may be associated with altered levels of many chemical messengers in the brain, such as serotonin, dopamine, and norepinephrine. Treatment may last for several months and requires regular follow-up. The medication should be taken as per the recommendations of a trained medical professional. It is not advisable to start or stop the tablet suddenly. Withdrawal symptoms may occur on abrupt discontinuation. It is recommended to take the pill at the same time daily for maximum efficacy.


Product Summary

Offer Price₹19.52
You Save₹3.44 (15% on MRP)
ContainsAmitriptyline(25.0 Mg)
UsesDepression, neuropathic pain, and migraine
Side effectsConstipation, urinary retention, Weight gain, Confusion, Orthostatic hypotension (sudden lowering of blood pressure on standing), Tiredness, Blurred vision, Dryness in mouth
Check more medicines with composition as Amitriptyline(25.0 Mg)

Uses of Ketrip 25 MG

  • Major Depressive Disorder
  • Neuropathic pain (pain that occurs due to damage to nerves)
  • Migraines

Contraindications of Ketrip 25 MG

  • Avoid using this medication in case of hypersensitivity reactions to these medications/ inactive ingredients.
  • This medication should not be used in patients with a recent history of heart conditions such as irregular heart rhythm or myocardial infarction (heart attack).
  • It is contraindicated in patients with angle-closure glaucoma.
  • The tablet should be discontinued before elective surgery to decrease the risk of interaction with anaesthetic agents.
  • This medication decreases the seizure threshold and should be used cautiously in epilepsy/ seizure disorders patients.
  • It should be used with caution in adolescents and young adults less than 24 years due to a potential increase in the risk of suicidal ideation.

Side effects of Ketrip 25 MG

  • Weight Gain
  • Constipation
  • Dry mouth
  • Dizziness
  • Headache
  • Somnolence/ Sleepiness
  • Urinary retention
  • Orthostatic hypotension (sudden lowering of blood pressure on getting up from a lying down position)
  • Dizziness

Precautions and Warnings of Ketrip 25 MG



Can I take Ketrip during pregnancy?
No, Ketrip should not be used during pregnancy as it can increase the chances of complications such as high blood pressure and affect the growing fetus. Consult your doctor, and inform them if you are pregnant or planning a pregnancy.

Breast Feeding

Can I take Ketrip while breastfeeding?
This medication is generally not advised while breastfeeding, as it is secreted in breast milk and can cause harm to the infant.


Can I drive if I have taken Ketrip?
Ketrip causes increased sleepiness, and it is not advisable to drive or perform any tasks that require focus.


Can I consume alcohol with the Ketrip?
Alcohol consumption while on this medication is contraindicated as mixing alcohol with this medication may cause increased sedation and other adverse effects.

Other General Warnings

Talk to your doctor if
  • You are on any other medications you are. Ketrip is metabolised using a group of enzymes that affect the blood levels of many other medications if taken at the same time.
  • If you experience any sudden mood changes or suicidal ideation.

Mode of Action of Ketrip 25 MG

How Does It Work?

Amitriptyline is a Tricyclic antidepressant (TCA) that raises the levels of certain chemical messengers in the brain called neurotransmitters. It works by increasing the neurotransmitters serotonin an...
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Directions for Use of Ketrip 25 MG

  • Ketrip Tablets should be taken as prescribed by the treating physician.
  • It is recommended to take this medication on a regular schedule, i.e., at the same time every day, for optimal pharmacological effects of this medication.
  • Swallow this medication as a whole. Do not crush, chew or break this tablet.
  • Do not stop the tablet or change the dose suddenly unless advised by a doctor.
  • This medication may require 2-4 weeks for onset of action. Inform your doctor regarding other medications you may be taking to review and prevent any associated effects of any medicine interaction.

Interactions of Ketrip 25 MG

Interactions with other medicines

  • This medication affects the heart rhythm and should not be used in addition to other medications with the same effect, as it may result in potentially life-threatening conditions. Examples include ast...
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  • This medication should not be used along with medications belonging to the class of monoamine oxidase inhibitors such as isocarboxazid, selegiline, etc. This can cause a dangerous increase in levels o...
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  • Ketrip should not be used with any other medications known to increase serotonin levels as it may result in a potentially fatal condition known as serotonin syndrome. These include methylene blue, tra...
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  • Ketrip should not be used with alcohol or other agents that act as depressants of the central nervous system.
  • Ketrip should not be mixed with medications belonging to the class of opioids or benzodiazepines such as alprazolam or clonazepam.

Interactions with food items

  • This medication has no specific interactions with food.

Storage and disposal of Ketrip 25 MG

Store in a cool and dry place away from direct light and moisture. Dispose of the medication after the date of expiration. Keep the tablets away from children and pets. Do not flush the medication dow...
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Dosage of Ketrip 25 MG


Amitriptyline overdose can have serious consequences. Patients may present with sedation, seizure, coma, increased heart rate, low blood pressure, dilated pupils, dry mouth, difficulty passing urine o...
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Missed a Dose

If you miss a dose of Ketrip, take the missed dose as soon as possible. If the duration missed is too long, or it is almost time for the next dose, you must not double the dose of the tablet. Instead,...
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Content Details


Dr. Bhavika Shah

MBBS, MD (Dermatology), DNB (Dermatology)

Frequently Asked Questions (FAQs)


Q: I have been using Ketrip for one month now and feel better. Can I stop taking it?

A: Ketrip must be used for the entire duration as prescribed by a doctor. It is not recommended to stop taking the tablet suddenly as it can result in withdrawal symptoms.

Q: I have been using Ketrip Tablets for a few days but feel no change. What should I do?

A: It takes 2-4 weeks for Ketrip to properly take effect. Take this medication as directed by your treating physician. It is important to review routinely for appropriate dose adjustment. Talk to your doctor for more information.

Q: I feel very hungry since I started Ketrip Tablets. My weight has also increased. Should I stop the tablet?

A: Weight gain and increased appetite are common side effects of Ketrip. The tablet must be continued as advised. Stopping the tablet abruptly can worsen the symptoms.
Product Details
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Last Updated on: 14 Apr 2022 | 03:15 PM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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