Jakavi 5 Mg Tablet 14
By NOVARTIS INDIA LTD
10 Tablet(s) in Strip
MRP ₹28750.00*
Inclusive of all taxes
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Jakavi 5 MG Description
Jakavi 5mg tablet is a prescription medication containing Ruxolitinib. It is used to treat blood disorders (myelofibrosis, polycythemia vera, and graft versus host disease) and relieves symptoms like
feeling tired, shortness of breath and easy bruising.
Product Summary
| Offer Price | ₹28750.00 |
| You Save | |
| Contains | Ruxolitinib(5.0 Mg) |
| Uses | treatment of myelofibrosis, polycythemia vera, and graft versus host disease |
| Side effects | anemia, thrombocytopenia, bruising, bleeding, dizziness |
| Therapy | ANTI-NEOPLASTIC |
Check more medicines with composition as Ruxolitinib(5.0 Mg)
Uses of Jakavi 5 MG
- Treatment of disease-related splenomegaly
- Primary myelofibrosis
- Polycythemia vera
- Graft versus host disease
Contraindications of Jakavi 5 MG
- Allergy to ruxolitinib or any other excipients
Side effects of Jakavi 5 MG
- Anaemia
- Thrombocytopenia
- Bruising
- Bleeding
- Dizziness
- Increased levels of alanine aminotransferase
- Increased aspartate aminotransferase
- High levels of triglycerides in the blood
Precautions and Warnings of Jakavi 5 MG
Pregnancy
Q:
Is Jakavi 5mg Tablet safe to use during pregnancy?
A:
The potential risk of Jakavi 5mg Tablet during pregnancy is unknown. However, as a precautionary measure, the use of these tablets is contraindicated in pregnancy. Please consult your doctor if you become pregnant during medication or plan to get pregnant.
Breast Feeding
Q:
Can I take Jakavi 5mg Tablet while breastfeeding?
A:
Jakavi 5mg tablets should not be used during breastfeeding as it is unknown whether ruxolitinib or its metabolites are excreted in human breast milk. However, the risk to the infant cannot be excluded, and therefore it should not be used.
Driving
Q:
Can I drive if I have consumed Jakavi 5mg Tablet?
A:
This medicine shows no effect on your driving ability. However, the patient's who experience dizziness should refrain from driving.
Alcohol
Q:
Can I consume alcohol with Jakavi 5mg Tablet?
A:
Alcohol is unsafe to consume with Jakavi 5 mg tablet; it may enhance the severity of the side effects.
Other General Warnings
Talk to your doctor if
- You have tuberculosis
- You have hepatitis B
- You have lipid abnormalities
- You have kidney impairment
- You have liver impairment
- You are galactose intolerant
- Your immunity is compromised
- You have a low platelet count
- You have serious bacterial or fungal infections
- You are allergic to ruxolitinib or any other excipients
- You are taking non-prescription or prescription medications
- You have a history of extended treatment with hydroxyurea or pre-malignant skin lesions
- You are taking other herbal supplements, nutritional supplements, vitamins or minerals
Mode of Action of Jakavi 5 MG
How Does It Work?
Ruxolitinib is a selective enzyme inhibitor that inhibits the signalling of cytokines and growth factors which are essential for the formation of cellular components of blood and immune function. As a result, it helps slow down the multiplication and spread of cancer cells....
Directions for Use of Jakavi 5 MG
- You should take it as advised by your doctor
- Do not break, crush or chew the tablet
- Swallow the tablet with a glass of water
- Do not exceed the number of doses
Interactions of Jakavi 5 MG
Interactions with other medicines
- Co-administration of ruxolitinib with strong CYP3A4 inhibitors results in an increase in area under curve(AUC) and Cmax of ruxolitinib by 33% and 91%
- Co-administration of dual CYP2C9 and CYP3A4 inhibitors results in an increase in ruxolitinib Cmax and AUC by 47% and 232%
- Rifampicin, when taken with ruxolitinib, lowers the AUC of ruxolitinib by 70% lower than after ruxolitinib monotherapy
- Erythromycin increases the Cmax and AUC by 8% and 27%
- Inhibition of P-glycoprotein and breast cancer resistance protein takes place in the intestine in the presence of ruxolitinib, leading to increased systemic exposure of substrates of these transporters...
Storage and disposal of Jakavi 5 MG
- Store it at room temperature in a dry place away from direct sunlight and moisture
- Keep this medication in the container it came in
- Keep it out of reach of children and pets
- The expired or unneeded tablets should be disposed of in a safe way
- Do not throw the tablets in household waste; talk to your pharmacist about the proper methods of disposal of medications
Dosage of Jakavi 5 MG
Overdose
In case of overdose, contact your doctor or rush to the nearest hospital immediately
Missed a Dose
If you forget to take a dose, take it as soon as you remember. If the next dose is approaching, skip the missing dose. Use your next dose at the same time every day. To catch up, do not increase the dose....
Content Details
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Frequently Asked Questions (FAQs)
Q: Is the active ingredient of Jakavi 5mg tablet an immunosuppressant?
A: Evidence has suggested that ruxolitinib exerts potent anti-inflammatory and immunosuppressive effects and therefore is considered to possess immunosuppressant effects.
Q: What is myelofibrosis?
A: Myelofibrosis is a bone marrow cancer that hinders the production of blood cells. It is a rare type of blood cancer and is considered a form of chronic leukaemia.
Q: Can myelofibrosis be genetically inherited?
A: Myelofibrosis is generally not genetically inherited as this type of mutation does not affect reproductive cells.
Product Details
Brand
JAKAVI
Expires on or After
19/07/2024
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Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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