Jakavi 5 Mg Tablet 14

By NOVARTIS INDIA LTD

10 Tablet(s) in Strip

MRP ₹28750.00*

Inclusive of all taxes

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Jakavi 5 MG Description

Jakavi 5mg tablet is a prescription medication containing Ruxolitinib. It is used to treat blood disorders (myelofibrosis, polycythemia vera, and graft versus host disease) and relieves symptoms like

feeling tired, shortness of breath and easy bruising.

Product Summary

Offer Price	₹28750.00
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Contains	Ruxolitinib(5.0 Mg)
Uses	treatment of myelofibrosis, polycythemia vera, and graft versus host disease
Side effects	anemia, thrombocytopenia, bruising, bleeding, dizziness
Therapy	ANTI-NEOPLASTIC

Check more medicines with composition as Ruxolitinib(5.0 Mg)

Precautions and Warnings

Uses of Jakavi 5 MG

Treatment of disease-related splenomegaly
Primary myelofibrosis
Polycythemia vera
Graft versus host disease

Contraindications of Jakavi 5 MG

Allergy to ruxolitinib or any other excipients

Side effects of Jakavi 5 MG

Anaemia
Thrombocytopenia
Bruising
Bleeding
Dizziness
Increased levels of alanine aminotransferase
Increased aspartate aminotransferase
High levels of triglycerides in the blood

Precautions and Warnings of Jakavi 5 MG

Pregnancy

Is Jakavi 5mg Tablet safe to use during pregnancy?

The potential risk of Jakavi 5mg Tablet during pregnancy is unknown. However, as a precautionary measure, the use of these tablets is contraindicated in pregnancy. Please consult your doctor if you become pregnant during medication or plan to get pregnant.

Breast Feeding

Can I take Jakavi 5mg Tablet while breastfeeding?

Jakavi 5mg tablets should not be used during breastfeeding as it is unknown whether ruxolitinib or its metabolites are excreted in human breast milk. However, the risk to the infant cannot be excluded, and therefore it should not be used.

Driving

Can I drive if I have consumed Jakavi 5mg Tablet?

This medicine shows no effect on your driving ability. However, the patient's who experience dizziness should refrain from driving.

Alcohol

Can I consume alcohol with Jakavi 5mg Tablet?

Alcohol is unsafe to consume with Jakavi 5 mg tablet; it may enhance the severity of the side effects.

Other General Warnings

Talk to your doctor if

You have tuberculosis
You have hepatitis B
You have lipid abnormalities
You have kidney impairment
You have liver impairment
You are galactose intolerant
Your immunity is compromised
You have a low platelet count
You have serious bacterial or fungal infections
You are allergic to ruxolitinib or any other excipients
You are taking non-prescription or prescription medications
You have a history of extended treatment with hydroxyurea or pre-malignant skin lesions
You are taking other herbal supplements, nutritional supplements, vitamins or minerals

Mode of Action of Jakavi 5 MG

How Does It Work?

Ruxolitinib is a selective enzyme inhibitor that inhibits the signalling of cytokines and growth factors which are essential for the formation of cellular components of blood and immune function. As a...

Directions for Use of Jakavi 5 MG

You should take it as advised by your doctor
Do not break, crush or chew the tablet
Swallow the tablet with a glass of water
Do not exceed the number of doses

Interactions of Jakavi 5 MG

Interactions with other medicines

Co-administration of ruxolitinib with strong CYP3A4 inhibitors results in an increase in area under curve(AUC) and Cmax of ruxolitinib by 33% and 91%
Co-administration of dual CYP2C9 and CYP3A4 inhibitors results in an increase in ruxolitinib Cmax and AUC by 47% and 232%
Rifampicin, when taken with ruxolitinib, lowers the AUC of ruxolitinib by 70% lower than after ruxolitinib monotherapy
Erythromycin increases the Cmax and AUC by 8% and 27%
Inhibition of P-glycoprotein and breast cancer resistance protein takes place in the intestine in the presence of ruxolitinib, leading to increased systemic exposure of substrates of these transporter...
Read more

Storage and disposal of Jakavi 5 MG

Store it at room temperature in a dry place away from direct sunlight and moisture
Keep this medication in the container it came in
Keep it out of reach of children and pets
The expired or unneeded tablets should be disposed of in a safe way
Do not throw the tablets in household waste; talk to your pharmacist about the proper methods of disposal of medications

Dosage of Jakavi 5 MG

Overdose

In case of overdose, contact your doctor or rush to the nearest hospital immediately

Missed a Dose

If you forget to take a dose, take it as soon as you remember. If the next dose is approaching, skip the missing dose. Use your next dose at the same time every day. To catch up, do not increase the d...

Content Details

WRITTEN BY

Dr. Sweta Athawale

MBBS

Frequently Asked Questions (FAQs)

Q: Is the active ingredient of Jakavi 5mg tablet an immunosuppressant?

A: Evidence has suggested that ruxolitinib exerts potent anti-inflammatory and immunosuppressive effects and therefore is considered to possess immunosuppressant effects.

Q: What is myelofibrosis?

A: Myelofibrosis is a bone marrow cancer that hinders the production of blood cells. It is a rare type of blood cancer and is considered a form of chronic leukaemia.

Q: Can myelofibrosis be genetically inherited?

A: Myelofibrosis is generally not genetically inherited as this type of mutation does not affect reproductive cells.

References

Jakavi 10mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2022 [cited 19 April 2022]. Available from: https://www.medicines.org.uk/emc/product/7786/smpc#

Product Details

Brand

JAKAVI

Expires on or After

27/03/2025

Other Products from this Brand

JAKAVI 5MG STRIP OF 10 TABLETS

Last Updated on: 27 Apr 2022 | 01:00 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

आंवला (Gooseberry in Hindi) के उपयोग, फ़ायदे और न्यूट्रिशनल वैल्यू

परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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