Jakavi 5Mg Strip Of 14 Tablets
10 Tablet(s) in StripMRP ₹28750.00
₹27312.50
5% OFF
Made by
NOVARTIS INDIA LTD
Dosage
TABLET
Expiry
Product Summary
| Uses | Myelofibrosis, Acute graft-versus-host disease |
| Therapy | Anti-neoplastic |
| Side effects | Weight gain, constipation, nausea |
| Salt Content | Ruxolitinib(5.0 Mg) |
Assurance
available
Regulated
Medical Description
Jakavi tablet contains ruxolitinib, a JAK inhibitor. It is used to treat myelofibrosis, polycythaemia vera, and certain cases of acute graft-versus-host disease (GvHD) when previous treatment has not worked well enough.
It works by blocking JAK1 and JAK2 proteins, which are involved in blood-cell production and immune responses. This helps reduce abnormal blood-cell activity and inflammation.
Common side effects include anaemia, low platelet or white blood cell counts, infections, headache, dizziness, and increased cholesterol levels. Regular blood tests are needed to monitor your blood counts, and your doctor may also check your liver, kidney, and cholesterol levels.
Tell your doctor if you have liver or kidney problems, an infection, hepatitis B, or tuberculosis, or if you take other medicines, supplements, or herbal products.
Uses
- Myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis, and post-essential thrombocythemia myelofibrosis.
- Polycythemia vera in patients who are resistant to or cannot tolerate hydroxyurea.
- Acute graft-versus-host disease (GvHD) in adults and children aged 12 years and older who have been previously treated unsuccessfully with steroid medications.
Contraindications
Side effects
- Anaemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
- Neutropenia (low neutrophil count)
- Infections, including urinary tract infections and herpes zoster
- Headache
- Dizziness
- Bruising and bleeding
- Increased cholesterol or triglyceride levels
- Weight gain
- Constipation
- Nausea
- Increased liver enzymes
- Increased blood creatinine
- Increased creatine phosphokinase (CPK)
- Serious infections, including tuberculosis, hepatitis B reactivation, herpes zoster, and sepsis
- Serious bleeding, particularly when blood platelet counts are low
- Thrombosis, including venous thromboembolism
- Progressive multifocal leukoencephalopathy (PML), a rare serious brain infection
- Non-melanoma skin cancers
- Major cardiovascular events, particularly in patients with cardiovascular risk factors
- Severe allergic reactions
Precautions and Warnings
Other General Warnings
- You have low blood cell counts or develop signs of infection.
- You have a serious infection, tuberculosis, or hepatitis B.
- You develop symptoms of shingles.
- You develop new memory, neurological, or mental health changes.
- You have high cholesterol or triglyceride levels.
- You are 65 years or older, or are a current or former long-term smoker.
- You have heart disease or risk factors for blood clots.
- You develop leg swelling or pain, chest pain, or shortness of breath.
- You have a history of skin cancer or precancerous skin lesions; regular skin checks may be recommended.
- You have kidney or liver problems, as your dose may need adjustment.
- Your symptoms return or worsen after stopping or interrupting Jakavi tablet.
Directions for Use
- Jakavi tablet should be taken orally, with or without food, as prescribed by your doctor.
- Take the medicine at approximately the same time each day. Do not change the dose or stop treatment without consulting your doctor.
Storage and disposal
- Store the medicine as directed on the product label.
- Keep Jakavi tablet out of the reach of children.
Dosage
Overdose
Missed a Dose
- If you miss a dose, skip it and take the next usual dose at the scheduled time.
- Do not take an extra dose to make up for the missed dose
How does this medicine work?
Interactions
Interactions with other medicines
- CYP3A4 inhibitors: Medicines such as ketoconazole, clarithromycin, and erythromycin may increase ruxolitinib levels and the risk of side effects. Your doctor may adjust the dose.
- CYP3A4 inducers: Medicines such as rifampicin, carbamazepine, and phenytoin may lower ruxolitinib levels and reduce its effectiveness.
- Tell your doctor if you take antibiotics or antifungal medicines, as some may interact with ruxolitinib.
- Always inform your doctor about all medicines, supplements, and herbal products you take.
References:
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Manufacturer Details
Brand:JAKAVI
Vendor Details
Fulfillment Information: Jakavi 5 MG Tablet (10) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.
In Case of Any Issues Contact Us
Email Id:care@pharmeasy.in
Phone Number:7666100300
Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703
Disclaimer
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
