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Do 25mg Tablet

10 Tablet(s) in Strip
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Do 25 MG Description

Do 25mg tablet is a prescription medicine used to manage different types of depression, such as psychotic and neurotic depression, as well as anxiety disorder. This medicine is also used to treat dep

ression in persons who have not responded to previous therapies. In some cases, Do 25mg tablets are used to manage chronic nerve pain. The main use of Do 25mg tablets is as antidepressant medication. The active ingredient in Do 25mg tablets is Dosulepin (also known as Dothiepin). The mode of action of the Do 25mg tablets is by raising the levels of a specific chemical messenger in the brain called serotonin, which is responsible for lowering mood swings. Do 25mg tablets help stabilise various chemical substances in the brain and lessens the symptoms of depression and other conditions. Directions for use of Do 25mg tablet should be strictly followed, as it has a relatively high toxicity in overdose. Sudden stoppage of this medicine can cause withdrawal symptoms like sweating, tremors, cold, etc. Do 25mg tablets are not recommended for children and adolescents below 18 years of age. The dosage should be monitored as it can increase the risk of suicidal thoughts and behaviour. For optimum benefit, the tablet should be taken at a fixed time each day to maintain stable medication levels in the body. Do 25mg tablets are not addictive, but weight gain, confusion, increased heart rate, etc., are some of the side effects of Do 25mg tablets.


Product Summary

Offer Price₹34.97
You Save₹6.17 (15% on MRP)
ContainsDosulepin / Dothiepin(25.0 Mg)
UsesDepression, Anxiety disorder, Nerve pain
Side effectsWeight gain or loss, Orthostatic hypotension, Excess sweating, Change in libido, Burning sensation in palms and soles, Slurred speech, Suicidal thoughts
Check more medicines with composition as Dosulepin / Dothiepin(25.0 Mg)

Uses of Do 25 MG

  • As per CDSCO, Do 25mg tablet is used for the following conditions:
  • It is used to treat depression, including sub-types of major depressive disorder such as psychotic depression (severe depressive disorder exhibits some form of psychotic symptoms like hallucinations, ...
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  • It is indicated in the treatment of depression unresponsive to other antidepressants.
  • It is used in the management of anxiety disorder.
  • It is also sometimes used for lowering various types of nerve pain like fibromyalgia. It is also used for migraines.

Contraindications of Do 25 MG

  • Do not take Do 25mg tablets or use caution:
  • If you have a known hypersensitive reaction to any of its components
  • If you already use other antidepressants or antipsychotics; this can cause hallucinations, seizures, and different life-threatening side effects
  • If you have any serious heart condition, like a recent heart attack, irregular heart rhythms
  • If you have a rare blood-related illness known as porphyria
  • If you were previously diagnosed with bipolar disorder or mania
  • If you have severe liver impairment
  • If you are currently expecting or planning a pregnancy
  • If you are breastfeeding
  • If you have closed-angle glaucoma (a severe eye condition)
  • If you notice any sudden mood changes and self-harming or suicidal thoughts
  • If you are under 18; Do 25mg tablets are not intended for use in children

Side effects of Do 25 MG

  • Side effects of Do 25mg tablets include:
  • Increased heart rate
  • Weight gain
  • Blurred vision
  • Sudden fall in blood pressure
  • Shaking of arms and feet
  • Low sex desire
  • Dry mouth

Precautions and Warnings of Do 25 MG



Can I take Do 25mg tablets during pregnancy?
Do 25mg tablets are unsafe during pregnancy. There are limited human studies, but animal studies have shown a risk to the foetus. Sometimes, doctors prescribe it during life-threatening conditions if they think the benefits outweigh the risks. Do not take it without consulting your doctor.

Breast Feeding

Can I take Do 25mg tablets while breastfeeding?
Do not use Do 25mg tablets while breastfeeding without consulting your doctor. There is inadequate information on the effects of this medicine in breastfed babies. Some human data suggest that it can be safe if the infant is older than two months. However, the baby will have to be monitored for drowsiness, nausea, vomiting, etc.


Can I drive if I have taken a Do 25mg tablet?
Do not drive after taking the Do 25mg tablets. This medicine can cause side effects like drowsiness, dizziness, and blurred vision that affect your ability to drive.


Can I consume alcohol with Do 25mg tablets?
Do not drink alcohol with Do 25mg tablets. Alcohol can interfere with the function of the medicine and cause exaggerated side effects like drowsiness, confusion, tremors, dizziness, etc.

Other General Warnings

Talk to your doctor if
  • Your blood pressure suddenly drops. Do 25mg tablets can lower blood pressure when you suddenly change your position.
  • You have prostate gland disorder. Do 25mg tablets can worsen the condition.
  • You use herbal medicines and supplements.
  • You are an older adult. The effect of Do 25mg tablets can last longer in the body because of slow metabolism. The dose should be monitored.
  • You have planned surgery or a dental procedure.
  • You have a kidney or liver condition. Dose adjustment might be needed.

Mode of Action of Do 25 MG

How Does It Work?

Do 25mg tablets contain dosulepin as their main ingredient. It belongs to the tricyclic antidepressant class of medicines. It works by stopping the reuptake of chemical messengers like norepinephrine ...
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Directions for Use of Do 25 MG

  • Take the Do 25mg tablet exactly as prescribed by the doctor.
  • Do not change the dose, even if you do not see its effects.
  • Do not try to break this tablet or chew it. Swallow the pill as a whole with a glass of water.
  • It is better to not take it with other medications without informing your doctor.
  • Do not use Do 25mg tablets if their packaging has been already opened.
  • Do not suddenly stop taking Do 25mg tablets as it can cause adverse effects from withdrawal.
  • You can take this medicine with or without food.

Interactions of Do 25 MG

Interactions with other medicines

  • Do 25mg tablets are known to interact with the following medicines:
  • Concomitant use with other antidepressant medicines like monoamine oxidase inhibitors (MAOIs) (linezolid, methylene blue, phenelzine, selegiline, etc.) can lead to severe side effects, like tremors, s...
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  • Concomitant use with other similar antidepressants like amitriptyline and imipramine can exaggerate the side effects of Do 25mg tablets.
  • Do not use Do 25mg tablets with other medicines that cause sedation and drowsiness, like tranquillisers, opioid or narcotic pain relievers, muscle relaxants, etc., without consulting a doctor.
  • Do 25mg tablets decrease the efficacy of antibiotics, antifungal, and migraine medicines.
  • Do 25mg tablets can interact with stomach ulcer medicine, antimalarial medicines, heart medicines, and blood thinners.

Interactions with food items

  • Avoid grapefruit and cranberries and their juice. They can increase medicine levels in the blood and cause adverse effects.

Storage and disposal of Do 25 MG

Store Do 25mg tablets at room temperature, away from wet surfaces, direct sunlight, and humidity. Keep away from children and pets. Check the expiration date before taking the tablets. Dispose of the ...
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Dosage of Do 25 MG


Do 25mg tablet has high toxicity levels and can easily lead to overdose. Overdose of the Do 25mg tablet can cause low blood pressure, low temperature, dry mouth, increased reflexes, seizures, difficul...
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Missed a Dose

If you have missed a Do 25mg tablet dose, try to take it as soon as you remember. If you recall the missed dose when it is almost time for the next one, skip the missed one and continue with your regu...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Are Do 25mg tablets habit-forming?

A: Do 25mg tablets are not habit-forming but can cause withdrawal side effects if stopped suddenly. It should be slowly tapered. Consult your doctor first

Q: Will regular intake of Do 25mg tablets cause weight gain?

A: Do 25mg tablets can change your appetite, leading to weight loss or gain, especially at the beginning of treatment. Its effects vary from person to person. Try to monitor your food and exercise regularly.

Q: When should I take the Do 25mg tablet?

A: You should follow your doctor's advice precisely regarding the medicine's dose, duration, and time. You can take it at any time, preferably at night, as this medication causes drowsiness. Try to take it at the same time every day.
Product Details
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Last Updated on: 04 Apr 2022 | 06:28 PM (IST)
The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here for detailed T&C.
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