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Dilona 25mg Inj 3ml

3ml Injection in I M Ampoule
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Diclofenac(25.0 Mg)
Therapeutic classification

Medical Description

Dilona 25mg Inj 3ml contains Diclofenac as its active ingredient. It is used to relieve pain in conditions like kidney stones, rheumatoid arthritis, gout, accidents, and fractures. This medicine should not be self-injected, it will be administered to you by a health professional. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding, and about all the medicines and supplements you take and all the conditions or diseases you suffer from before you start this medicine.
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Uses of Dilona 25mg Inj 3ml

  • Dilona 25mg Inj 3ml is used for relieving extreme and serious painful conditions like kidney stones, rheumatoid arthritis, and osteoarthritis, gout, accidents, and fractures.
  • It is also used to treat or prevent post-operative pain and pain after surgery in hospitals.

Contraindications of Dilona 25mg Inj 3ml

  • If you are allergic to Diclofenac or any of the ingredients of Dilona 25mg Inj 3ml.
  • If you have active liver or kidney failure problem.
  • If you have a history of a blood clotting disorder or you tend to bleed easily.
  • If you had or have an active stomach or intestinal ulcer or bleeding problems.
  • If you have a history of stomach ulcers or bleeding due to the use of painkillers.
  • If you recently had surgery or operation, which has associated risk of bleeding.
  • If you are pregnant, especially in the last trimester, you have a history of an asthma attack, or you have dehydration.
  • If you are using medicine to stop blood clottings like Heparin, or other pain killers like Ibuprofen, Celecoxib, etc.
  • If you have experienced an episode of allergic reaction upon painkiller use like asthma, skin rashes, swelling & nasal congestion.
  • If you are suffering from brain and heart diseases like heart attack, stroke, heart failure, problems with blood circulation, or any circulatory disease.
  • This medicine is not recommended for children below the age of 14.

Side effects of Dilona 25mg Inj 3ml

  • Headache
  • Dizziness or spinning head
  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Bloating
  • Weight loss
  • Skin rashes, swelling, and pain at the injection site

Precautions and Warnings of Dilona 25mg Inj 3ml


Can I take Dilona 25mg Inj 3ml during pregnancy?
It is not advisable to take this medicine during pregnancy, especially in the third trimester of pregnancy. It may affect the development of the growing foetus, which can lead to cardiac malformations, abnormal abdominal growth, and abnormal kidney function. In pregnant women, it can prolong or delay the labour and increase the risk of bleeding. If you think you are pregnant or think you may be pregnant, then discontinue the treatment and seek a safer alternative immediately.

Breast Feeding

Can I take Dilona 25mg Inj 3ml while breastfeeding?
Diclofenac passes into breast milk in small amounts. Therefore, it is advisable to stop breastfeeding during the treatment to avoid undesirable side effects in the baby.


Can I drive if I have consumed Dilona 25mg Inj 3ml?
You may experience dizziness, visual disturbance, spinning head, sleepiness, or drowsiness while on treatment. So, it is advisable to drive carefully or be cautious while operating machines.


Can I consume alcohol with Dilona 25mg Inj 3ml?
You should avoid consuming alcohol along with this medicine as it can increase the risk of liver disease and stomach bleeding and other side effects of this medicine.

Other General Warnings

Talk to your doctor if
  • You are already using any other painkillers.
  • You have kidney failure, and you experience swelling and water retention.
  • You develop skin allergies like skin rashes, itching, papules, blisters, etc.
  • You have a hereditary disorder of intolerance to some sugars like lactose and glucose.
  • You are suffering from autoimmune disorders like systemic lupus erythematosus.
  • You are trying to conceive or taking treatment for infertility, should discontinue this medicine.
  • You have asthma, or you are prone to seasonal allergies, rhinitis, and other lung and throat problems.
  • You have a history of stomach or bowel disorders like gastrointestinal bleeding or Crohn's disease.
  • You are an elderly patient, or with low body weight, your doctor may reduce your dose of this medicine.
  • You have liver disease, it may get exacerbated. Therefore, close monitoring of liver function is required.
  • You have any heart problems like high blood pressure, high cholesterol, or diabetes, or you are an active smoker.
  • You develop stomach or intestinal bleeding problems during the treatment, the risk is more if you are using aspirin.

Mode of Action of Dilona 25mg Inj 3ml

How Does It Work?

This medicine acts by interfering with the production of a chemical called prostaglandins, which is responsible for the sensation of pain and swelling. It reduces pain and swelling.

Directions for Use of Dilona 25mg Inj 3ml

  • This medicine will be given to you in a hospital by your doctor or nurse as an injection.
  • Please do not self-inject this medicine.

Interactions of Dilona 25mg Inj 3ml

Interactions with other medicines

  • Concomitant use of Diclofenac with medicines like water pills and other blood pressure medicines like Furosemide, Propranolol, Atenolol, and Telmisartan can decrease the blood pressure lowering effects and thus should be cautiously used, especially in elderly patients.
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  • Water pills like chlorothiazide, chlorthalidone and immunosuppressants like Tacrolimus and Ciclosporin may increase the potassium level if taken along with Dilona 25mg Inj 3ml.
  • Concomitant use of anticoagulants like Warfarin and medicines to treat mental conditions like Escitalopram and Fluoxetine can increase the risk of bleeding and ulcers.
  • Using antidiabetics along with this medicine can affect your blood sugar level. The doctor may ask you to monitor blood sugar levels regularly.
  • Medicines used to modify immune responses like Methotrexate, Ciclosporin, and Tacrolimus, if taken along with this medicine, can cause kidney problems.
  • Antibiotics like ciprofloxacin, norfloxacin can cause fits (you have a history of fits or seizures) if taken along with this medicine.
  • Diclofenac should not be used for 10-12 days after the use of Mifepristone, as it can reduce the effect of this medicine.
  • Other medicines like Phenytoin for fits, Sulfinpyrazone and Voriconazole, Colestipol, Cholestyramine, Lithium used to treat mental conditions and Digoxin used to treat heart failure should be used cautiously.
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Storage and disposal of Dilona 25mg Inj 3ml

  • Store the medicine below 30°C in a cool and dry place away from light.
  • Keep it out of the reach of children and pets.
  • Any unused portion should not be stored and should be discarded properly.

Dosage of Dilona 25mg Inj 3ml


  • Your doctor or nurse will give this injection to you in the hospital or clinic. Therefore, it is less likely to provide you with an overdose of this medicine.
  • However, if you experience headache, nausea, vomiting, stomach pain, diarrhoea, unconsciousness, excitation, dizziness, drowsiness, fits, difficulty in breathing, and depression right after taking this injection, please inform your doctor immediately.
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  • A significant overdose of this injection can lead to liver damage and kidney failure.

Missed a Dose

Your doctor or nurse will monitor you on when the injection should be given to you, thus, it is unlikely that you will miss the dose. However, if you think your doctor or nurse might have missed a dose, inform them.
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Content Details


Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)


Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)


Q: Why do pain killers cause gastrointestinal bleeding?

A: Pain killers are known to work by interfering with the production of a chemical called prostaglandins. Certain prostaglandins help in protecting the stomach lining from the corrosive effects of stomach acid, as well as play a role in maintaining the natural and healthy condition of the stomach lining. Painkillers reduce the formation of prostaglandins and can lead to gastrointestinal bleeding.

Q: Is Dilona 25mg Inj 3ml addictive?

A: No, this medicine is not addictive, but it is advised not to give this medicine if anyone else has the same condition as you.

Q: Can I take Dilona 25mg Inj 3ml for fever?

A: No, this injection is given in the cases of acute pain and not for fever.

Q: What is the route of administration of this injection?

A: This injection can be given into the veins or deltoid muscles depending on the convenience of the patient. This medicine is given in a hospital or a clinic by a doctor or nurse.

Q: How to inject Dilona 25mg Inj 3ml?

A: This injection is given by a doctor or a nurse in a hospital or a clinic. Do not try to self-inject this medicine.

Q: How long does the effect of this injection last?

A: It varies among individuals on case to case basis depending on the physiological nature of an individual. However, the effects last for approximately 12 hours.

Q: Is Dilona 25mg Inj 3ml safe during pregnancy?

A: Do not take it during pregnancy, especially in the third trimester of pregnancy. It may affect foetal development. It can also delay your delivery.

Q: How to store Dilona 25mg Inj 3ml?

A: Store the injection below 30°C. Once opened, the unused portion should not be stored or used.

Other Variants for

Dilona 25mg Inj 3ml

Last Updated on: 31 Jul 2020 | 07:00 PM (IST)
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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  • Uses
  • Contraindications
  • Side effects
  • Precautions and Warnings
  • Mode of Action
  • Directions for Use
  • Interactions
  • Storage and disposal
  • Dosage
  • FAQs
  • References
  • Other Variants
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