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Crizenta 250Mg Bottle Of 60 Capsules

60 Capsule(s) in Bottle

MRP25000.20

20000.16

20% OFF

333.34/capsule (Inclusive of all taxes)
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  • Crizenta 250Mg Bottle Of 60 Capsules

Made by

ADLEY FORMULATION

Dosage

CAPSULE

Expiry

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Product Summary

Uses
Non-small-cell lung cancer (NSCLC)
Side effects
Nausea, diarrhea, vomiting, constipation, and decreased appetite
Salt Content
Crizotinib(250.0 Mg)
3 Step Quality
Assurance
Cash on delivery
available
NPPA
Regulated

Medical Description

Crizenta capsule is a prescription oral targeted anticancer medication that belongs to a class of drugs known as receptor tyrosine kinase inhibitors (TKIs). It is primarily used for the treatment of adult patients with advanced non-small cell lung cancer (NSCLC) whose tumors are ALK (anaplastic lymphoma kinase)-positive or ROS1-positive. The medication works by inhibiting specific abnormal enzymes that promote cancer cell growth and survival, blocking tumor proliferation and inducing cell death.

Treatment with Crizenta capsule requires regular medical supervision by an experienced oncologist. Because this medication can impact heart rhythm, liver function, vision, and lung health, regular clinical monitoring is required.. Blood tests, electrocardiograms (ECGs), and eye assessment when clinically indicated are important components of treatment monitoring.

Patients receiving this therapy must be informed about potential risks, including visual disturbances, gastrointestinal effects, elevated liver enzymes, and changes in cardiac rhythm. Close communication with your healthcare team is vital to ensure that side effects are managed promptly.

Uses

Crizotinib is used to treat locally advanced or metastatic non-small-cell lung cancer (NSCLC)

Contraindications

If you have a known hypersensitivity or severe allergic reaction to crizotinib or any of the inactive ingredients in the capsule formulation.

Side effects

Very common side effects (occurring frequently):
  • Visual disturbances (such as flashes of light, blurred vision, or increased sensitivity to light)
  • Gastrointestinal disturbances (nausea, diarrhea, vomiting, constipation, and decreased appetite)
  • Edema (swelling, particularly in the hands, ankles, or feet)
  • Fatigue and asthenia (weakness)
  • Elevated liver enzymes (transaminases)
  • Dizziness and neuropathy (numbness or tingling)
Other reported side effects:
  • Taste disturbances (dysgeusia)
  • Rash and dry skin
  • Low white blood cell counts (neutropenia) or anemia
  • Joint pain (arthralgia)
  • Bradycardia (slow heart rate)
  • Photosensitivity
Serious but less common side effects:
  • Serious heart rhythm problems, including changes in the QT interval.
  • Serious lung problems, such as interstitial lung disease or pneumonitis.
  • Severe liver problems, including liver failure.
  • Severe or persistent vision problems, including vision loss.
  • Kidney problems, including kidney cysts or reduced kidney function.
  • Heart failure.
  • A hole or tear in the stomach or intestine (gastrointestinal perforation)

Precautions and Warnings

Pregnancy

Pregnancy

Crizenta capsule may harm the unborn baby and should generally not be used during pregnancy. Women who could become pregnant should use effective contraception during treatment and for a few weeks after the final dose, as recommended by your doctor.

Breast Feeding

Breast Feeding

No. Breastfeeding is not recommended while taking Crizenta capsule due to the potential risk to the nursing infant.

Alcohol

Alcohol

There is no specific established alcohol interaction with crizotinib. However, alcohol may worsen fatigue, dizziness, or gastrointestinal symptoms. Discuss alcohol consumption with your doctor.

Driving

Driving

Use caution. Crizenta capsule can cause visual disturbances (such as light flashes or blurred vision) and dizziness that may impair your alertness and driving safety, especially in low-light conditions.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You experience sudden shortness of breath, a dry cough, or breathing difficulties, which may indicate pneumonitis.
  • You notice yellowing of the skin or eyes, dark urine, or upper abdominal pain (signs of liver strain).
  • You notice persistent changes in your vision.
  • You develop a very slow heartbeat, particularly with dizziness, fainting, or low blood pressure.
  • You have a history of heart disease, QT prolongation, electrolyte abnormalities, or are taking medicines that affect heart rhythm.
  • You develop severe abdominal pain, particularly with fever or other symptoms of gastrointestinal complications.

Directions for Use

  • Take Crizenta capsule orally exactly as your doctor prescribed.
  • Swallow the capsules whole with a glass of water; do not crush, chew, open, or dissolve them.
  • You may take this medication either with or without food.
  • Continue your treatment course as long as you observe clinical benefit or until your doctor advises discontinuation. Never alter your dose without consulting your physician.

Storage and disposal

  • Store the capsules according to the product label
  • Keep out of the reach of children and pets in a secure medical environment.
  • Return any unused or expired capsules to your pharmacist for safe disposal.

Quick Tips

  • Be cautious when driving or operating machinery at night, as crizotinib frequently causes visual disturbances like bright flashes of light.
  • Keep all scheduled blood tests, liver-function assessments, ECGs, and other monitoring appointments.
  • Report any new or worsening cough, shortness of breath, or chest pain to your doctor immediately, as lung inflammation requires urgent care.
  • Report severe or persistent changes in vision promptly.
  • Tell your healthcare providers you are taking this medication before any other medical procedures or eye examinations.
  • Stay well hydrated, and tell your doctor early if you experience persistent nausea or diarrhea.

Dosage

Overdose

  • If an overdose is suspected, contact your doctor immediately or seek emergency medical care. There is no specific antidote.
  • Treatment focuses on managing symptoms and close medical monitoring.

Missed a Dose

  • If you miss a dose of Crizenta capsule, take it as soon as you remember, unless it is less than 6 hours until your next scheduled dose.
  • If so, skip the missed dose and take your next dose at the usual time.Do not take two doses at the same time to make up for

How does this medicine work?

Crizenta capsule is a targeted cancer medicine that blocks proteins called ALK, ROS1, and MET, which can send signals that help cancer cells grow and multiply.In some cancers, changes in these genes produce abnormal proteins that promote uncontrolled cell growth. Crizenta capsule blocks these signals, helping to slow or stop cancer growth and may cause some cancer cells to die.

Interactions

Interactions with other medicines

  • Ketoconazole, clarithromycin, and ritonavir may increase crizotinib levels and the risk of side effects.
  • Rifampicin, carbamazepine, and St. John’s wort may reduce crizotinib levels and make it less effective.
  • Tell your doctor if you take medicines that can affect heart rhythm or slow your heartbeat, as crizotinib can also affect heart rhythm.
  • Some medicines with a narrow safety range may interact with crizotinib and require careful monitoring.
  • Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, supplements, and herbal products you take.

Interactions with food items

  • Crizotinib can generally be taken with or without food.
  • Avoid grapefruit, grapefruit juice, and products containing grapefruit extract while taking crizotinib, as they may increase the amount of crizotinib in your blood and increase the risk of side effects.

Frequently Asked Questions (FAQs)

Crizotinib often causes visual symptoms, such as bright light flashes, blurred vision, or light sensitivity. These effects typically occur shortly after taking a dose and are generally mild and temporary, but persistent, worsening, or severe visual changes should be reported promptly.
Your doctor may check your heart rhythm with an ECG and monitor blood electrolyte levels before and during treatment. The frequency depends on your individual risk and may increase if you develop vomiting, diarrhoea, dehydration, or kidney problems, or take other medicines that affect heart rhythm.
Gastrointestinal side effects are very common. Stay well-hydrated, eat smaller meals, and inform your doctor promptly so they can prescribe safe anti-nausea or anti-diarrhea medications to help you manage these symptoms.

References:

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Manufacturer Details

Brand:CRIZENTA

Manufacturer Name:ADLEY FORMULATION

Address:ADLEY FORMULATION

Country of Origin:India

Vendor Details

Fulfillment Information: Crizenta 250 MG Capsule (60) will be delivered by a licensed retail pharmacy nearest to your location. Order acceptance and fulfillment are dependent upon the verification of your doctor's valid prescription (where applicable) and the current stock of this medicine.

In Case of Any Issues Contact Us

Email Id:care@pharmeasy.in

Phone Number:7666100300

Address:D-37/1, Opp. Sandoz, TTC Industrial Area, MIDC Industrial Area, Turbhe, Navi Mumbai, Maharashtra 400703

Disclaimer

The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. You should not use the information provided herein to diagnose, prevent, or cure a health problem. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. Please click here  for detailed T&C.

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