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Clonil 25mg Tablet

10 Tablet(s) in Strip
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Clonil 25 MG Description

Clonil Tablet is a prescription medicine used for treating obsessive-compulsive disorder, depression, and phobic (fear) states. It consists of clomipramine as its active ingredient. It is an antidepr

essant medication. It works by increasing a specific chemical messenger in the brain called serotonin. It is responsible for reducing mood swings and providing a calming effect. Obsessive-compulsive disorder (OCD) causes a pattern of repetitive behaviour and unwanted thoughts. Depression is a mood disorder, which causes sad feelings, irritability, loss of interest in anything, etc. There are many kinds of phobic states like fear of flying, heights, agoraphobia (fear of open places and crowds), etc. Clonil Tablet helps stabilise the chemical substances and lower the symptoms of these conditions. Do not use this Clonil Tablet without the advice of a doctor. Do not stop this medicine suddenly, as it can cause withdrawal symptoms like sweating, shaking, irritation, etc. Its usage should be monitored as it can cause suicidal thoughts. Take it at a fixed time each day to maintain stable levels in the body.


Product Summary

Offer Price₹52.93
You Save₹9.34 (15% on MRP)
ContainsClomipramine(25.0 Mg)
UsesObsessive-compulsive disorder, Phobic states, Depression
Side effectsSleepiness, Dry mouth, Nausea, Vomiting, Diarrhoea, Constipation, Nervousness, Decreased sexual drive or ability, Decreased concentration and memory
Check more medicines with composition as Clomipramine(25.0 Mg)

Uses of Clonil 25 MG

  • As per CDSCO, Clonil tablet is used in the
  • Treatment of obsessive-compulsive disorder
  • Treatment of phobic states
  • Treatment of depression (when sedation is required)

Contraindications of Clonil 25 MG

If you are allergic to clomipramine, avoid taking Clonil Tablet. If you are using other antidepressant medications like MAO inhibitors, etc. If you recently had a heart attack. If you have been dia...
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Side effects of Clonil 25 MG

  • Sleepiness
  • Dry mouth
  • Nausea
  • Vomiting
  • Diarrhoea
  • Nervousness
  • Decreased sexual drive or ability
  • Decreased concentration and memory

Precautions and Warnings of Clonil 25 MG



Can I take the Clonil Tablet during pregnancy
No, Clonil Tablets are not usually recommended during pregnancy. There is not enough data available on the side effects of these tablets on pregnant women and unborn developing babies. Consult your doctor before using Clonil Tablets.

Breast Feeding

Can I take the Clonil Tablet while breastfeeding?
No, you cannot take Clonil Tablet if you are breastfeeding without consulting your doctor. The limited evidence available indicates that this medicine should be used with caution in breastfeeding women. The amount of this medicine in breast milk may be sufficient to cause withdrawal symptoms in breastfed infants.


Can I drive if I have taken the Clonil Tablet?
No, it can be unsafe to drive after taking the Clonil Tablet. It can cause drowsiness, dizziness, difficulty concentrating, etc., which can impede your ability to drive.


Can I consume alcohol with the Clonil Tablet?
No, do not consume alcohol with a Clonil Tablet. It can cause increased side effects like extreme drowsiness, lethargy, vomiting, agitation, blurry vision, muscle stiffness, sweating, etc.

Other General Warnings

Talk to your doctor if
  • You experience suicidal thoughts after taking Clonil Tablet.
  • You are using tobacco products. Cigarette smoking may reduce the effectiveness of Clonil medication.
  • You have a surgery or a dental procedure planned.
  • You are an elderly patient over the age of 65. The dose needs to be carefully monitored to prevent excessive side effects.
  • You have a history of diabetes, irregular heartbeat, problems with your blood pressure, thyroid problems, etc.
  • You have a kidney condition.
  • You are using any medicinal herbs or supplements like St. John's wort. It can lead to a serious condition called serotonin syndrome (serotonin toxicity), which can cause life-threatening side effects.

Mode of Action of Clonil 25 MG

How Does It Work?

Clonil Tablet has clomipramine as its active substance. It is a tricyclic antidepressant medicine. It works by stopping the reuptake of chemical messengers like noradrenaline and serotonin, neurotrans...
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Directions for Use of Clonil 25 MG

  • Take the Clonil Tablet in the exact dosage and at the same time every day as prescribed by the doctor.
  • Do not exceed the dosage of Clonil Tablet, even if you cannot notice its effects.
  • Take this tablet as a whole with a glass of water, without breaking, chewing or crushing it.
  • Do not use Clonil Tablet with other medications without informing your doctor.
  • Do not discontinue this medication abruptly, as it can have unwanted symptoms due to its withdrawal effects.

Interactions of Clonil 25 MG

Interactions with other medicines

  • Do not use Clonil Tablet if you are already using other antidepressants like MAO inhibitors such as linezolid, methylene blue, phenelzine, selegiline, etc., as they can lead to severe side effects.
  • Do not take other antidepressants with a similar composition like sertraline, fluoxetine, paroxetine, etc. They can exaggerate the side effects of this medicine.
  • Do not use this medication with other medicines that cause sedation and drowsiness, like tranquillisers, without consulting a doctor.
  • Some of the other medications that can react with Clonil Tablet and cause an adverse reaction are:
  • Blood thinners such as warfarin
  • Heart medication like digoxin
  • Alcohol dependency medicine - disulfiram
  • Anti-seizure medications like phenytoin, phenobarbital
  • Oral contraceptive pills

Interactions with food items

  • Avoid drinking grapefruit juice and cranberry juice, or eating those fruits, while you are taking Clonil Tablets, as they can increase the levels of this medicine in your blood. It can lead to unwante...
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Storage and disposal of Clonil 25 MG

Store Clonil Tablets in dry conditions and at room temperatures. Keep this medicine away from wet surfaces, direct sunlight, and humid conditions. Keep Clonil Tablet away from children and pets. Disp...
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Dosage of Clonil 25 MG


  • Overdose of Clonil Tablets can cause symptoms like extreme drowsiness, nausea, irregular or fast heartbeat, dizziness, fainting, seizures, decreased urination, unusual movements, slow breathing, and l...
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Missed a Dose

If you have missed a single dose of the Clonil Tablet, take it as soon as you recall. If you remember missing a dose of this medicine when it's almost the time to take the next Clonil tablet, skip the...
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Content Details


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can I take a Clonil Tablet if I am diabetic?

A: Patients with diabetes should be monitored for worsening blood sugar levels when under treatment with Clonil Tablets, especially if the dosage has been altered. Studies have shown that diabetes prevalence was higher in patients treated with this medicine than in patients who were not, independent of their age and BMI. Please consult your doctor.

Q: Can I gain weight while using Clonil Tablet?

  • A study has shown that some people gained weight while using Clonil Tablet for a long duration. Try to be more active and eat healthy food, to maintain a stable weight.
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Last Updated on: 28 Feb 2022 | 09:37 AM (IST)
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