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Clomach 25mg Tablet

10 Tablet(s) in Strip
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Clomach 25 MG Description

Clomach 25 mg tablets belong to the class of atypical antipsychotics. It is primarily used to treat schizophrenia. Schizophrenia is a condition characterised by symptoms like delirium, hallucinations

, and abnormal thinking processes. Clomach 25 mg tablet contains Clozapine as its active ingredient. Some of the most common side effects of the medicine are nausea, indigestion, decrease in appetite, sweating, tremors, diarrhoea, and low blood pressure levels. You may experience restlessness and involuntary movement of muscles. Most of the symptoms are mild and should go away within a few days if using the medicine. However, if these side effects bother you, you should consider consulting a doctor. You should inform your doctor about all the medicines you take before starting this medicine. This would prevent any adverse interaction between the medication. It would also help tell your doctor about all the pre-existing conditions, like epilepsy, diabetes, kidney, and liver diseases. It would help if you tried to take the medicine at a particular time of the day. This should replenish the chemical substances in the nerve endings.


Product Summary

Offer Price₹23.89
You Save₹4.22 (15% on MRP)
ContainsClozapine(25.0 Mg)
Side effectsHeadache, Restlessness, Dryness of mouth, Increased salivation
Check more medicines with composition as Clozapine(25.0 Mg)

Uses of Clomach 25 MG

  • Clomach 25 mg tablets are used to treat schizophrenia.

Contraindications of Clomach 25 MG

  • Clomach 25 mg tablets are contraindicated in the following cases:
  • If you have a condition called prolactinoma. Prolactinoma is a tumour in the endocrine gland of our body. Clomach 25 mg tablet can worsen the condition
  • If you have had allergic reactions to its use in the past
  • If you are pregnant or planning to get pregnant
  • If you are a child below 15 years of age
  • If you are breastfeeding female as it decreases the secretion of breastmilk
  • If you have pre-existing kidney diseases, Clomach 25 tablets should be prescribed with caution as the medicine is excreted out through the kidney.
  • If you have liver disease, the dose should be modified
  • If you have heart disease, Clomach 25 mg tablet should be prescribed with caution as it can increase the chances of stroke
  • If you have a history of convulsions, dose modification should be done as Clomach 25 mg tablets decrease the threshold of seizure

Side effects of Clomach 25 MG

  • The side effects of Clomach 25 mg include the following:
  • Constipation
  • Dry mouth
  • Weight gain
  • Low blood pressure levels
  • Involuntary muscle contractions
  • Restlessness

Precautions and Warnings of Clomach 25 MG



Can I take a Clomach 25 mg tablet during pregnancy?
Clomach 25 tablets should not be taken during pregnancy. It causes abnormal movements of limbs and withdrawal symptoms like agitation, feeding difficulties, decrease in respiratory rate, tremor, and sedation in babies.

Breast Feeding

Can I take Clomach 25 mg tablet while breastfeeding?
It is not advisable to take Clomach 25 tablets during breastfeeding as it can pass through the breastmilk and cause adverse effects like sedation, lethargy, poor feeding, and low blood pressure levels in the baby. Clomach 25 tablets can decrease the secretion of breastmilk.


Can I drive if I have taken Clomach 25 mg tablet?
You should not drive after taking a Clomach 25 mg tablet because this medicine causes drowsiness and lethargy. You should avoid operating any machinery as it causes impairment in judgement.


Can I consume alcohol with Clomach 25 mg tablet?
You should not consume alcohol with a Clomach 25 mg tablet as the combination increases the severity of side effects like drowsiness and palpitations.

Other General Warnings

Talk to your doctor if
  • You should be careful if you have diabetes and take a Clomach 25 mg tablet. Blood sugar should be monitored at regular intervals.
  • You have liver disease and have been prescribed Clomach 25 mg tablets; you should regularly get your liver function tests.
  • You must get your blood examination done regularly as Clomach 25 mg tablets can decrease blood cell counts.
  • You should be careful if you are above the age of 65 and taking Clomach 25 mg tablets as this medicine increases the chances of stroke in the elderly.
  • You must inform your doctor about all the medicines you are taking so that no adverse reaction occurs in the future.
  • You experience difficulty breathing, fever, chest pain, or fast breathing, as these symptoms may signify myocarditis (swelling of heart muscle) or cardiomyopathy (thickening of the heart muscle).
  • You had any heart disease in the past. Clomach 100 mg tablets may increase the chances of heart failure.
  • You had episodes of convulsion in the past.
  • You smoke as tobacco decreases the efficacy of Clomach 100 mg tablets.

Mode of Action of Clomach 25 MG

How Does It Work?

Clomach 25 mg tablet contains Clozapine as its active ingredient. Clozapine belongs to the group of atypical antipsychotics. This medicine binds to the dopamine receptors in the nerve endings. An incr...
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Directions for Use of Clomach 25 MG

  • Take this medicine exactly as prescribed by your doctor.
  • Do not exceed the recommended dosage.
  • Seek medical help immediately, if you have any side effects.
  • Make sure that the treatment is complete.
  • Do not discontinue using this medication without consulting your physician first.
  • Keep the medicines in the container with the lid tightly closed.

Interactions of Clomach 25 MG

Interactions with other medicines

  • Antiarrhythmics (flecainide) can increase the risk of developing bradycardia, arrhythmia, hypotension, and heart failure.
  • Antihypertensive medicines (reserpine, methyldopa, clonidine, guanfacine) can decrease heart rate and force contraction with Clomach 25 mg tablets.
  • Insulin can cause hypoglycemia if used with the Clomach 25 mg Tablet.
  • Antacids (Cimetidine, omeprazole) slow down the absorption of the Clomach 25 mg tablet.
  • Clomach 25 mg tablet prolongs the action of anti-depolarizing muscle relaxants.
  • Antidepressants (fluoxetine) cause drowsiness and sedation if used with the Clomach 25 mg tablet.
  • Sedatives, hypnotics (benzodiazepines, barbiturates) can cause extreme drowsiness and a decrease in respiratory rate if used with the Clomach 25 mg tablet.
  • Alcohol can cause sleepiness and palpitations if taken with the Clomach 25 mg tablet.
  • Monoamine oxidase inhibitors (Selegiline) can cause symptoms like palpitations, flushing, convulsions, and coma if used with the Clomach 25 mg tablet.

Interactions with food items

  • There are no known adverse reactions between food and Clomach 25 mg tablets. It would help if you avoided caffeinated beverages while taking this medicine.

Storage and disposal of Clomach 25 MG

Keep this medicine packed in the packet or container. Keep it in a cool and dry place, at a temperature below 30°C. Store it according to the package or label’s directions. Dispose of the unused table...
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Dosage of Clomach 25 MG


Taking more than the recommended dose of Clomach 25 mg tablets can cause symptoms like decreased heart rate, low blood pressure, sedation, convulsions, and coma. You should immediately consult a docto...
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Missed a Dose

If you miss a Clomach 25 mg tablet dose, you should take it as soon as possible. However, if it is time for the next dose to be taken, skip it and continue with your regular schedule. You should not t...
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Content Details


Dr. Jagruti Jain

M.B.B.S., M.D., D.N.B., General Medicine

Frequently Asked Questions (FAQs)


Q: For how long should Clomach 25 mg tablets be taken?

A: Clomach 25 mg tablets should be taken at a dose and for a duration as prescribed by your doctor. You may start noticing improvement in your symptoms after a week of taking the medicines. However, it would help if you did not discontinue taking the medicine without consulting a doctor. Sudden discontinuation of the medication may cause withdrawal symptoms like nausea, sleepiness, numbness, agitation and headache. The dose of the medicine is gradually reduced, and the response is continuously monitored before stopping the treatment.

Q: When should Clomach 25 mg tablets be taken?

A: You should take Clomach 25 mg as recommended by your doctor. It should be taken at a particular time of the day to replenish the exhausted chemical substances in your brain. If you face side effects like drowsiness or dizziness after taking this medicine, you should take this medicine in the evening.

Q: Can Clomach 25 mg tablets cause addiction?

A: No cases of addiction with Clomach 25 mg tablets have been reported. It does not have any abuse potential as well.
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Last Updated on: 30 Mar 2022 | 10:25 AM (IST)
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