Cladrim 10 Mg Injection 1

• Active Hairy Cell Leukaemia (HCL) defined by clinically significant:
• Anaemia (low red blood cell count)
• Neutropenia (low white blood cell count)
• Thrombocytopenia (low platelets)
• Disease-related symptoms

• Fever
• Fatigue
• Nausea
• Rash
• Headache
• Vomiting
• Diarrhoea
• Cough
• Dizziness
• Decreased appetite
• Muscle pain
• Pain
• Shortness of breath
• Abdominal pain
• Constipation
• Weakness
• Chills
• Insomnia
• Itching

• Severe bone marrow suppression: May cause very low blood cell counts, increasing the risk of infection, weakness, or bleeding. Report fever, chills, unusual bleeding, or bruising immediately.
• Serious infections: Low white blood cell counts can increase the risk of serious infections, including pneumonia and sepsis.
• Neurological toxicity: Rarely, it may cause severe weakness or paralysis. Report any new or worsening neurological symptoms immediately.
• Kidney toxicity: May occur, particularly with high doses. Report reduced urine output or other kidney-related symptoms promptly.
• Severe allergic or skin reactions: Seek urgent medical attention for widespread rash, blistering, skin peeling, or breathing difficulty.

Other General Warnings

• You have an active infection, as Cladrim injection can suppress the immune system and may increase the risk of serious infection.
• You have low blood-cell counts, as Cladrim injection treatment can further reduce red cells, white cells, and platelets.
• You have kidney impairment, as caution is advised because renal toxicity has been reported, particularly with high-dose treatment.
• You develop severe weakness, difficulty moving your arms or legs, or other neurological symptoms, as serious neurological toxicity has been reported.
• You develop unusual bruising or bleeding, as this may indicate a low platelet count.
• You develop fever, particularly during the first month after treatment, because fever and serious infections are common during this period.

• Cladrim injection is given as a continuous intravenous infusion by a doctor or nurse. Your doctor determines the dose and duration.
• Do not change, shorten, extend, or repeat the prescribed dose without the treating doctor's decision.
• If neurological or kidney toxicity develops, the doctor may delay or discontinue treatment. Because this is an intravenous chemotherapy medicine, patients should not attempt to administer or adjust Cladrim injection themselves.

• Store Cladrim injection according to the storage conditions specified on the product label and package insert.
• Diluted solutions should be prepared and stored only according to the manufacturer's instructions and administered within the specified period.
• Vials are for single use only; unused medicine should be discarded appropriately.
• Because Cladrim injection is a cytotoxic medicine, its preparation and disposal require appropriate precautions according to institutional and applicable local requirements.
• Keep the medicine away from children and pets.

• Cladrim injection should be given only under the supervision of a doctor or nurse.
• Blood counts should be monitored during the period following treatment.
• Patients may experience symptoms such as fever, chills, or other signs of infection. If you have unusual bleeding or bruising, inform your doctor immediately.
• Inform your doctor about kidney or liver problems before treatment.
• Avoid live attenuated vaccines while receiving Cladrim injection unless your treating doctor specifically advises otherwise.
• Women should use highly effective contraception during Cladrim injection treatment because it may harm an unborn baby.

Missed a Dose

Overdose

• No specific antidote is available for Cladrim injection overdose. As Cladrim injection is always given by a doctor or nurse in a clinical setting, the risk of receiving an incorrect dose is very low.
• If an overdose is suspected, urgent medical attention is required, and the patient will need close monitoring of blood counts and organ function, with supportive treatment for any complications that arise.

Interactions with other medicines

Interactions with food items