Adrea 500Mg Strip Of 10 Capsules

• Changes in blood counts (low white cells, low platelets, anaemia)
• Loss of appetite
• Nausea, vomiting, diarrhoea, constipation
• Mouth sores (stomatitis)
• Hair thinning or loss
• Rash, skin darkening under the nails (melanonychia)
• Fever
• Macrocytosis (enlarged red blood cells)

• Severe suppression of bone marrow function
• A form of anaemia caused by red blood cell breakdown (haemolytic anaemia)
• Skin cancers with long-term use
• Skin ulcers or tissue damage related to blood vessel inflammation (vasculitic toxicity), particularly in patients with a history of interferon treatment
• Lung scarring, inflammation, or breathing difficulty
• Leg ulcers, particularly with long-term treatment.

Other General Warnings

• You have a history of low blood counts or bone marrow problems.
• You have a history of skin cancer or notice any new or changing skin lesions.
• You develop breathlessness, persistent cough, or other breathing difficulties.
• You develop leg ulcers or other skin sores.
• You are taking antiretroviral medicines for HIV.
• You are planning to have children, as this medicine may affect fertility.

• Take Adrea capsule exactly as your doctor prescribed.
• Swallow the capsule whole with water; do not open, crush, or chew it, as it contains a cytotoxic drug.
• If you touch a broken or leaking capsule, wash the area thoroughly with soap and water.
• Keep all scheduled blood test appointments, as your dose may be adjusted based on your blood counts.

• Store below 25 degrees C, with excursions permitted between 15 and 30 degrees C. Keep the container tightly closed.
• Keep out of the reach of children and pets.
• This is a hazardous cytotoxic medicine; return any unused or expired capsules to your pharmacy for safe disposal rather than discarding them in household waste.

• Keep all scheduled blood test appointments so your doctor can monitor your blood counts.
• Use sun protection, as this medicine has been linked to an increased risk of skin cancer with long-term use.
• Report any yellowing of the skin or eyes, or unusual paleness, to your doctor, as these can be signs of a blood disorder.
• Report any skin ulcers, especially on the legs, to your doctor promptly.
• Tell your doctor about any HIV medicines you are taking, as certain combinations require closer monitoring.

Overdose

Missed a Dose

Interactions with other medicines

• Antiretroviral medicines used for HIV, particularly didanosine and stavudine: combined use has been associated with pancreatitis, liver toxicity, and severe nerve damage.
• Other medicines that suppress the bone marrow may increase the risk of low blood counts.
• Hydroxyurea may enhance the immunosuppressive effects of live vaccines. Discuss vaccination with your doctor before receiving any vaccine, particularly live vaccines.
• Tell your doctor about all other prescription medicines, over-the-counter medicines, and herbal supplements you are taking.

Interactions with food items