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Vitamin B6 / Pyridoxine+Isoniazid

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Molecule Summary

Uses
Tuberculosis (TB)
Therapy
Anti-Tubercular
Side Effects
Rash, peripheral neuropathy, fever, increased liver enzymes, jaundice, hepatitis
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Molecule Description

Vitamin B6 / Pyridoxine+Isoniazid is used in tuberculosis (TB) therapy. It is a combination of two medicines, Isoniazid and Pyridoxine. It stops the TB causing bacteria from multiplying.

Uses

  • Treatment of Tuberculosis (TB)

Contraindications

When should one not use Vitamin B6 / Pyridoxine+Isoniazid

  • Peripheral Neuropathy (weakness, numbness or pain in the hands and feet due to damage to nerves)
  • Acute liver disease
  • Jaundice
  • Allergy to Vitamin B6 / Pyridoxine+Isoniazid or any of its components

Side effects

Common side effects of this drug are:

  • Rash
  • Peripheral neuropathy (tingling and numbness of hands and feet)
  • Fever
  • Jaundice
  • Hepatitis

Precautions and Warnings

Pregnancy

Pregnancy

It may be possible that using Vitamin B6 / Pyridoxine+Isoniazid during pregnancy is dangerous. Before providing it to you, your doctor will consider the advantages and possible hazards. Please consult your doctor.

Breast Feeding

Breast Feeding

It may be safe to take Vitamin B6 / Pyridoxine+Isoniazid during nursing. Please consult your doctor.

Driving

Driving

Vitamin B6 / Pyridoxine+Isoniazid may induce adverse effects that damage your driving abilities, like excessive drowsiness or dizziness. It may have an impact on your driving skills.

Alcohol

Alcohol

While taking Vitamin B6 / Pyridoxine+Isoniazid, drinking alcohol may induce flushing, nausea, chest discomfort, and low blood sugar levels.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You should take Vitamin B6 / Pyridoxine+Isoniazid as your doctor prescribes.
  • You should not miss any doses and complete the whole course of the medication.
  • Your doctor may check your liver function, eyesight, and thyroid function during therapy with this medicine.
  • You have diabetes or kidney disease; tell your doctor before taking this medicine.

Mode of Action

How Does It Work?

Vitamin B6 / Pyridoxine+Isoniazid is a combination of two medicines: Isoniazid and Pyridoxine. Isoniazid is an antibiotic that prevents tuberculosis bacilli from making their protective layer. It eliminates the disease by killing the bacilli. Isoniazid may lead to nerve damage. Hence, Vitamin B6 or Pyridoxine helps to prevent it.

Interactions

Interactions with other medicines

  • Sedative medicines (used for sedation)
  • Anti-anxiety medicines
  • Levodopa (anti-Parkinson's medicine)
  • Caffeine
  • Phenobarbital (Anti-epileptic)
  • Conjugated Estrogens (Used in menopausal syndrome)
  • Phenytoin (Anti-epileptic)

Interactions with food items

  • It may be advised to not take Vitamin B6 / Pyridoxine+Isoniazid with foods containing tyramine (like tofu, kimchi, pickled cucumbers, dried sausages or smoked fish), cheese, smoked salmon, poultry, and alcohol. Also, avoid grapefruit juice since there may be adverse reactions.

Dosage

Overdose

If you believe you have taken an extra dose, contact the emergency room immediately. Seek emergency medical help.

Missed a Dose

Take Vitamin B6 / Pyridoxine+Isoniazid as soon as you remember if you miss a dose. However, omit the missing amount and return to your usual schedule when your next dosage is approaching. Do not take an extra dose.

Frequently Asked Questions (FAQs)

Vitamin B6 / Pyridoxine+Isoniazid treats tuberculosis. It destroys and inhibits the development of TB causing bacteria. Even if you feel okay, you should complete the course of the medicines as prescribed. Otherwise, your symptoms may come back or worsen.

Vitamin B6 / Pyridoxine+Isoniazid may start acting within a week. However, sometimes it may take longer for you to feel better completely. Do not stop or modify the medicine doses on your own.

No, Vitamin B6 / Pyridoxine+Isoniazid is not a habit-forming medicine. Please use it only according to your prescription.

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