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Venlafaxine

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Molecule Description

Venlafaxine is a medicine used to treat depression. It is also used to treat general anxiety disorder, social anxiety disorder and panic disorder. This medicine belongs to a group of Serotonin and Norepinephrine Reuptake Inhibitors.This medicine works by increasing the action of a chemical called Serotonin in the brain. Venlafaxine affects the neurotransmitters which is a chemical that is present in the nerves of the brain. It helps in the communication of one nerve cell to another.

Uses

  • Depression
  • Anxiety disorder
  • Panic disorder
  • Post-Traumatic Stress Disorder
  • Attention deficit disorder
  • Neuropathic pain
  • Hot flashes due to hormonal chemotherapy

Contraindications

When should one not use Venlafaxine

  • If you are allergic to the medication or any excipients
  • Any medical history of bleeding problems, glaucoma, high blood pressure, heart problems, high cholesterol, kidney disease, liver disease, seizure disorder and thyroid disease

Side effects

Common side effects of this drug are:

  • Common side effects:
  • Headache
  • Drowsiness
  • Dizziness
  • Blurred vision
  • Dryness of mouth
  • Poor appetite
  • Weight loss
  • Nausea
  • Constipation
  • Impotence
  • Serious side effects:
  • Attempts to commit suicide
  • Aggressive and violent behavior
  • Agitation
  • Restlessness
  • Seizures

Precautions and Warnings

Pregnancy

Pregnancy

Avoid this medicine if you are pregnant or planning for pregnancy. Your doctor will prescribe the Venlafaxine medicine to you during pregnancy only if the benefit to you exceeds the potential risk to the fetus.

Breast Feeding

Breast Feeding

The medicine passes through the breast milk and can cause serious effects in a breastfeeding child. Hence it must not be taken during breastfeeding.

Driving

Driving

Change in eyesight (blurred vision), confusion, dizziness are the possible side effects after taking Venlafaxine. If you experience these, do not drive.

Alcohol

Alcohol

Venlafaxine increases the risk of sleepiness with alcohol.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • Before taking Venlafaxine, consult with the doctor and tell him/ her if you have had:
  • Heart problems
  • Diabetes
  • History of eye problems any eye surgery
  • Other psychotic problems like aggressive behavior, seizures or fits

Mode of Action

How Does It Work?

Venlafaxine acts by increasing the levels of Serotonin and Norepinephrine in the brain. These are the chemicals used for communication by the brain. Venlafaxine inhibits the reuptake of these two chemicals. Thus, this medicine affects chemicals in the brain that may be unbalanced in people with depression.

Interactions

Interactions with other medicines

  • Venlafaxine can react with other medications like nutritional supplements, vitamins, herbs
  • Tell your doctor if you are taking other medicines for cough, fever, and cold, diabetes, high blood pressure, weight loss or antipsychotics medicine

Interactions with food items

If you have any food allergy, consult with the doctor.

Dosage

Overdose

The most commonly reported symptoms of overdosage include rapid heartbeat, changes in level of consciousness (ranging from excessive sleep to coma), dilated pupils of eyes, seizures, and vomiting. Seek emergency medical attention immediately if you suspect overdose.

Missed a Dose

If you missed any dose, take it as soon as you remember. Don’t take the missed dose if it is almost time for your next scheduled dose. Do not take more medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

The medicine is to be taken orally. The dosage of Venlafaxine must be as prescribed by the doctor. Follow all directions on the prescription label without altering the prescribed dose.

The medicine should not be used in children and adolescents under 18 years of age.

Half-life of this medicine is 5-11 hours so that it can work up to 10-22 hours in body.

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