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Varicella Vaccine Live Attenuated

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Molecule Summary

Uses
Chickenpox
Therapy
Vaccine
Side Effects
Fever, Rash, Irritability, Pain and redness at the injection site, Upper respiratory infection.
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Molecule Description

Varicella Vaccine Live Attenuated is a live attenuated vaccine used to prevent chickenpox (varicella) in individuals aged 12 months and older. It contains a weakened form of the varicella-zoster virus, which helps the immune system recognize and build protection against the actual virus without causing the disease. This vaccine does not treat an active chickenpox infection but is used to prevent future infections. It is administered by a healthcare professional and should never be self-administered. The vaccine works by stimulating the body's immune response to produce antibodies against the varicella virus. These antibodies remain in the system and help prevent infection if the person is exposed to the virus later in life. It is essential to follow any post-vaccination care instructions provided by the healthcare provider. Before receiving Varicella Vaccine Live Attenuated, it is important to inform the doctor about any existing medical conditions, such as kidney or liver disease, or a history of organ transplantation. Salicylates, such as aspirin, should not be taken for six weeks following vaccination due to a potential association with Reye syndrome. Individuals who are in close contact with people who are immunocompromised, pregnant without a history of chickenpox, or newborns born before 28 weeks gestation should also take precautions. If a rash develops after vaccination, medical advice should be sought promptly. The vaccine should be stored at a temperature between 2°C to 8°C and protected from light. It must be kept out of the reach of children and properly disposed of by healthcare professionals.

Uses

Varicella Vaccine Live Attenuated is used to prevent chickenpox (varicella) in individuals 12 months of age and older.

Contraindications

When should one not use Varicella Vaccine Live Attenuated

  • If you have an allergy to any varicella vaccine, any of the excipients of Varicella Vaccine Live Attenuated, or neomycin (which may be present as a trace residue).
  • If you have blood dyscrasias, leukaemia, lymphomas of any type, or other malignant neoplasms affecting the hemic and lymphatic systems.
  • If you are receiving immunosuppressive therapy (including high doses of corticosteroids).
  • If you have severe humoral or cellular (primary or acquired) immunodeficiency, such as severe combined immunodeficiency, agammaglobulinaemia, AIDS, or symptomatic HIV infection, or specific low age-related CD4+ T-lymphocyte percentages in children.
  • If you have a family history of congenital or hereditary immunodeficiency, unless your immune competence has been demonstrated.
  • If you have active untreated tuberculosis.
  • If you have any illness with a fever greater than 38.5°C
  • If you are pregnant
  • Pregnancy should be avoided for one month following vaccination.

Side effects

Common side effects of this drug are:

  • Fever
  • Rash
  • Irritability
  • Pain and redness at the injection site
  • Upper respiratory infection

Precautions and Warnings

Pregnancy

Pregnancy

Pregnant women should not receive Varicella Vaccine Live Attenuated. Pregnancy should be avoided for one month after vaccination. Women planning to become pregnant should be advised to postpone vaccination.

Breast Feeding

Breast Feeding

Varicella Vaccine Live Attenuated is generally not recommended for breastfeeding mothers due to the potential risk of transmitting the vaccine viral strain to infants.

Driving

Driving

Varicella Vaccine Live Attenuated has no or negligible influence on the ability to drive and use machines.

Alcohol

Alcohol

Limited information is available on the interaction of alcohol with Varicella Vaccine Live Attenuated.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have a family history of congenital or hereditary immunodeficiency.
  • You are HIV-infected or suspect you may be.
  • You are in close contact with individuals who are immunocompromised, pregnant (without varicella history), or newborns born before 28 weeks of gestation.
  • You are currently taking or have recently received immune globulins or other blood products.
  • You plan to take or are currently taking salicylates (like aspirin) or products containing salicylates.
  • You have kidney disease or have had a kidney transplant.
  • You have liver disease or any ongoing liver-related condition.
  • You or someone close to you develops a rash after vaccination.
  • You are pregnant or planning to become pregnant.
  • You are caring for or living with individuals who are at high risk of complications from varicella infection.
  • You have any known immune system problems or are taking medications that suppress the immune system.

Mode of Action

How Does It Work?

Varicella Vaccine Live Attenuated, commonly known as the chickenpox vaccine, is an injection that contains a weakened form of the chickenpox virus. It helps your body's immune system learn to fight off the actual chickenpox virus if you come into contact with it. Varicella Vaccine Live Attenuated does not treat an active chickenpox infection.

Interactions

Interactions with other medicines

  • Do not take aspirin or salicylates for 6 weeks after receiving the vaccine, as this helps prevent the risk of Reye's syndrome.
  • Inform your doctor if you have recently received immune globulins or blood products, as these may reduce the vaccine's effectiveness.
  • If you need a TB (PPD) skin test, schedule it before, on the same day, or 4 weeks after Varicella Vaccine Live Attenuated to avoid false test results.
  • Varicella Vaccine Live Attenuated can be administered with other live vaccines. If not given together, wait 1 month after a measles-containing vaccine before receiving Varicella Vaccine Live Attenuated. For spacing between chickenpox vaccines: Children (12 years and under) should wait at least 3 months between doses, while teens and adults can receive the second dose 1 month after the first.
  • You can take Varicella Vaccine Live Attenuated at the same time as M-M-R II (Measles, Mumps, Rubella), Hib vaccine (Haemophilus influenzae type b), and Hepatitis B (recombinant) vaccine.
  • Discuss with your doctor any other medicine, herbal preparation and supplements you are taking currently to avoid any possible drug interactions.

Dosage

Overdose

This medicine will be given by a doctor or nurse; thus, chances of overdose are unlikely. However, if you experience any discomfort or specific symptoms, inform your doctor or reach out to the nearest hospital.

Missed a Dose

It is unlikely that the dose of this medicine will be missed if you are monitored in a healthcare setting. However, if you have missed a dose of this medicine, please inform your doctor or nurse immediately.

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