What should I discuss with my healthcare expert before taking this medicine?

Spironolactone

Uses	Fluid Retention, High Blood Pressure, Low Potassium, Heart Failure
Therapy	Anti-Hypertensive
Side Effects	Nausea, Vomiting, Dizziness

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Molecule Description

Spironolactone is a medicine that prevents your body from absorbing too much salt and water.

Uses

This medicine is used to treat fluid retention (edema) in people with congestive heart failure, cirrhosis of the liver or a kidney disorder called nephrotic syndrome. This medicine is also used to treat or prevent hypokalemia (low levels of potassium in the blood).

Contraindications

When should one not use Spironolactone

You are allergic to spironolactone
You cannot pass urine
You have severe kidney disease
You have an extreme weakness, loss of weight and low blood pressure
Potassium levels are high in your body

Side effects

Common side effects of this drug are:

Vomiting
Diarrhea
Stomach pain or cramps
Dry mouth and thirst
Dizziness
Unsteadiness and headache
Gynecomastia (enlarged breast tissue in men) and breast pain in women
Irregular menstrual periods and postmenopausal vaginal bleeding
Erectile dysfunction in men

Precautions and Warnings

Pregnancy

There is not much adequate data about the safety of this medicine in pregnancy. Spironolactone should not be used during pregnancy.

Breast Feeding

It is not recommended to use while breastfeeding a baby.

Driving

If during Spironolactone treatment, you feel dizziness, sleepiness or blurred vision, then try to avoid driving.

Alcohol

Intake of alcohol should be avoided while taking this medicine as both can low your blood pressure drastically.

Other General Warnings

Talk to your doctor if

Have kidney disease
Have any problems in passing urine
Have heart failure
Are pregnant
Have electrolyte imbalance
Do not take potassium supplements if you are taking this medicine as both can increase potassium in the blood which can be harmful

Mode of Action

How Does It Work?

This medicine lowers blood pressure and swelling by removing the extra water and electrolytes from the body without the loss of potassium.

Interactions

Interactions with other medicines

Metformin
Non-Steroidal Anti-Inflammatory Drugs
Angiotensin-Converting Enzyme Inhibitors (ACEI's)

Interactions with food items

It has food interactions with high-potassium fruits like papaya, cantaloupe, prune juice, honeydew melons, bananas, kiwis, oranges and orange juice. High potassium vegetables such as tomatoes, tomato juice, white and sweet potatoes, asparagus, pumpkin and Brussels sprouts should also be avoided.

Dosage

Overdose

Seek emergency medical care if you think you had an overdose of Spironolactone. Overdose symptoms may include red skin rash, drowsiness, confusion, nausea, vomiting or diarrhea.

Missed a Dose

If you missed any dose, take it as soon as possible. If it is time for your next dose, skip the missed dose and continue the regular dosing schedule. Do not take an extra dose of medicine to compensate for the missed dose.

Frequently Asked Questions (FAQs)

Give a detailed account of your medical and surgical history. Also, mention to your doctor all the prescription and non-prescription medicines, herbal preparations and nutritional supplements that you may be taking before starting this medication.

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