Silymarin is a standardized extract of milk thistle seeds (Silybum Marianum L.), containing a mixture of Flavonolignans. This medicine is a herbal supplement which causes detoxification and protection of liver function.
Uses of Silymarin
For supportive treatment in chronic liver disease and cirrhosis.
Contraindications of Silymarin
When should one not use Silymarin
If you are allergic to Silymarin or any ingredient of this medicine.
Side effects of Silymarin
Common side effects of this drug are:
- Intestinal gas
- Fullness or pain in stomach
- Loss of appetite
- Rashes and itching
Precautions and Warnings of Silymarin
Can I take Silymarin during pregnancy?
You should not take this medicine during pregnancy. Limited information is available about its safety in pregnancy, hence do not take this medicine unless it is considered essential by a physician.
Can I take Silymarin while breastfeeding?
Take this medicine only when advised by your doctor.
Can I drive if I have consumed Silymarin?
Limited information is available about the effect of this medicine while driving.
Can I consume alcohol with Silymarin?
It is known to show interactions with alcohol and hence alcohol must be avoided.
Other General Warnings
Talk to your doctor if
- You have high-risk factors include under-active thyroid or excessive use of alcohol or diabetes, breast cancer, uterine cancer, endometriosis, uterine fibroids
- You should inform your doctor before surgery regarding all the products you use (including prescription medicines, nonprescription medicines and herbal products)
Mode of Action of Silymarin
How Does It Work?
This medicine protects liver cells from toxic chemicals and medicines by antioxidant and anti-inflammatory effects. It may also enhance the effects of estrogen.
Interactions of Silymarin
Interactions with other medicines
Interactions with food items
No information is available on interactions of Silymarin when taken with food, consult your doctor or pharmacist for further details.
Dietary Restrictions of Silymarin
No information is available on dietary restrictions while you are taking Silymarin, consult your doctor or pharmacist for further details.
Dosage of Silymarin
If you think you have taken an overdose of Silymarin, contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you miss a dose, follow the regular dosing schedule. Do not double the dose.
Frequently Asked Questions (FAQs)
Q: What should I discuss with my healthcare expert before taking this medicine?
- Tell your doctor if you have-
- Allergy to this medicine
- Breast cancer
- Uterine cancer
- Uterine fibroids
- CDSCO. Silymarin. [Accessed 13 Sept.2019] (online):
- Mayoclinic. Silymarin. [Accessed 13 Sept.2019] (online):
- WebMD. Silymarin. [Accessed 13 Sept.2019] (online):
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): The National Library of Medicine (US); 2006-. Milk Thistle. [Updated 2019 May 1]:
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)
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