Ranibizumab

Uses	Eye diseases
Therapy	Anti-VEGF Agent
Side Effects	Conjunctival haemorrhage, eye pain, increased intraocular pressure, foreign body sensation in eyes

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Molecule Description

Ranibizumab is a medication used to treat eye problems that cause vision loss in adults. These problems include age-related macular degeneration, diabetic macular oedema, diabetic retinopathy, swelling caused by retinal vein occlusion, and abnormal blood vessel growth in the eye. It can also be used to treat a serious eye condition in premature babies. You should not administer this medication at home. Common adverse effects include conjunctival haemorrhage, eye discomfort, eye floaters, increased intraocular pressure, and eye inflammation. However, if you suffer any adverse effects for an extended period of time or if you notice any other symptoms that you believe are related to this medication, please notify your doctor. Driving after receiving this medicine is not recommended since it may induce blurring of vision.

Uses

Ranibizumab is used to treat eye problems causing vision loss in adults, including age-related macular degeneration, diabetic macular oedema, diabetic retinopathy, retinal vein occlusion, abnormal blood vessel growth, and a serious eye condition in premature babies.

Contraindications

When should one not use Ranibizumab

Known active or suspected ocular or periocular infections
Known active severe intraocular inflammation

Side effects

Common side effects of this drug are:

Nasopharyngitis
Anaemia
Anxiety
Headache
Vitritis: Inflammation inside the eye
Vitreous detachment: The gel-like substance inside your eye pulls away from the retina
Retinal haemorrhage: Bleeding in the back of your eye
Visual disturbance: Changes in how you see
Eye pain: Pain in or around your eye
Vitreous floaters: Small spots or shapes that float in your vision
Conjunctival haemorrhage: Redness in the white part of your eye due to bleeding
Eye irritation: Feeling of discomfort in your eye
Foreign body sensation in eyes: Feeling like something is in your eye
Lacrimation increased: More tearing or watering of the eyes
Blepharitis: Inflammation of the eyelids
Dry eye: Not enough tears to keep your eyes wet
Ocular hyperaemia: Redness of the eye
Eye pruritus: Itchy eyes

Precautions and Warnings

Pregnancy

Clinical data regarding Ranibizumab effects on pregnant women is currently unavailable, but it may potentially harm embryos and fetuses. It is advisable to avoid the use of ranibizumab during pregnancy unless absolutely necessary. If planning to conceive, wait for three months after the last dose of the medication. Women should use reliable contraception while undergoing treatment with ranibizumab.

Driving

Do not operate a vehicle or engage in tasks requiring mental concentration until you understand how Ranibizumab affects you.

Alcohol

It is unknown whether consuming alcohol with Ranibizumab is safe.

Other General Warnings

Talk to your doctor if

You have a risk of eye infections and other eye issues from Ranibizumab.
You experience a temporary increase in eye pressure after injection.
You experience side effects like eye pain, redness, blurred vision, or increased light sensitivity.

Mode of Action

How Does It Work?

It works by inhibiting a protein known as vascular endothelial growth factor (VEGF), which halts the development and seepage of abnormal blood vessels in the eye(s) that can lead to vision loss.

Dosage

Overdose

Your doctor or nurse will give this medicine, so it is unlikely that you overdose on this medicine.

Missed a Dose

You will be monitored by your doctor or nurse as to when the medicine should be given to you. It is unlikely that the dose will be missed. However, if you think your doctor or nurse might have missed a dose, inform them.