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Progesterone

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Molecule Summary

Uses
Gynaecological disorders
Therapy
Drugs For Female Infertility, Hormone Replacement Therapy
Side Effects
Drowsiness, bloating, diarrhoea, spotting, breast tenderness
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Molecule Description

Progesterone is used to treat gynaecological disorders associated with low progesterone levels. Progesterone is a female hormone synthesized in the body and plays a key role in regulating the menstrual cycle and maintaining pregnancy. This medicine works by supplying adequate levels of the hormone progesterone and mimicking its action in the body. It is used for the treatment of disorders related to the female reproductive cycle, infertility, irregular menses, and abnormal uterine bleeding.

Uses

  • For the treatment of premenstrual syndrome, absence of menses, irregular menses and abnormal uterine bleeding.
  • To support the early phase of pregnancy in women who have experienced vaginal bleeding during early pregnancy and have inadequate or low levels of progesterone.
  • For the treatment of infertility, preventing preterm delivery and mood disorder following childbirth.
  • Hormone replacement therapy in women having menopause. It is given along with oestrogen to post-menopausal women.
  • This medicine is also used to support pregnancy and fertility outcomes during assisted reproductive procedures.

Contraindications

When should one not use Progesterone

  • If you are allergic to any of the ingredients of the medicine.
  • If you have or ever had breast cancer.
  • If you experience abnormal vaginal bleeding which is not being treated.
  • If you recently had a heart attack or stroke.
  • If you have a blood clotting disorder such as thrombosis, deep vein thrombosis (clots in blood vessels of legs) and blood clots in the lungs.
  • If you have severe liver disease.

Side effects

Common side effects of this drug are:

  • Drowsiness
  • Abdominal bloating
  • Breast tenderness
  • Soreness
  • Diarrhoea
  • Flatulence
  • Short menstrual cycle
  • Intermittent bleeding or spotting

Precautions and Warnings

Pregnancy

Pregnancy

This medicine can be taken during pregnancy if it is prescribed by your doctor.

Breast Feeding

Breast Feeding

Components of this medicine pass into the breastmilk, however, its effect on breastfed infants is unknown. Consult your doctor for further advice.

Driving

Driving

This medicine can make you feel drowsy and sleepy, caution is advised while driving or using machines if affected.

Alcohol

Alcohol

There is no known interaction between this medicine and alcohol. Consult your doctor if you drink too often. Consumption of alcohol during pregnancy should be avoided.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You experience abnormal vaginal bleeding or have a vaginal infection.
  • You have epilepsy, migraine, asthma, liver, heart or kidney dysfunction, diabetes or photosensitivity, or you are a breastfeeding mother; careful observation is required.

Mode of Action

How Does It Work?

This medicine contains a man-made form of the female hormone progesterone. Progesterone plays a key role in regulating the menstrual cycle and maintaining pregnancy. This medicine works by replenishing the levels of the female hormone, progesterone in the body and thereby corrects the conditions related to reduced levels of this hormone.

Interactions

Interactions with other medicines

  • Certain medicines affect the way Progesterone works or Progesterone itself can affect the action of other medicines taken at the same time.
  • Tell your doctor about all the medicines, supplements, herbals you are currently taking or might take before taking this medicine.
  • Especially, if you are taking an antifungal medicine containing ketoconazole inform your doctor.

Dosage

Overdose

If you think you have taken too much of this medicine, contact your doctor immediately or visit the nearest hospital. Symptoms of an overdose include drowsiness, dizziness, sleepiness or painful menstruation.

Missed a Dose

If you have missed taking any dose of this medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Take this medicine as advised by your doctor. This medicine should be taken at a fixed time to gain optimum benefits.

Progesterone is used for the treatment of gynaecological disorders associated with decreased levels of a female hormone progesterone. It is used in females to treat abnormal uterine bleeding, absence of or irregular menstruation, to support pregnancy, as hormone replacement therapy in women having menopause and for fertility related problem.

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