Piroxicam

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Molecule Description

Piroxicam is a Non-Steroidal Anti-Inflammatory Drug (NSAID), used to decrease the pain and inflammation in persons of rheumatoid arthritis and osteoarthritis.

Uses

Osteoarthritis
Ankylosing Spondylitis
Other musculoskeletal disorders

Contraindications

When should one not use Piroxicam

Do not take if you are allergic to Piroxicam or any ingredient of this medicine
Allergic to Aspirin or other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

Side effects

Common side effects of this drug are:

Nausea and vomiting
Stomach ache
Bleeding in stomach/ulcer
Ringing in the ears
Rise in blood pressure
Constipation
Itching and rash
Breathlessness
Kidney disorder - swelling of legs and decreased urination
Liver disorder – nausea, stomach pain, jaundice (yellowing of the skin or eyes), dark coloured urine, loss of appetite, etc.
Heart disease, swelling of feet, unusual tiredness, unusual weight gain

Precautions and Warnings

Pregnancy

Medication of Piroxicam during pregnancy may be harmful for baby. Consult your doctor if you are pregnant or are planning a pregnancy before using this medicine.

Breast Feeding

Piroxicam can pass into breast milk and may harm the baby. Do not use this medication without doctor’s advice.

Driving

If this medicine makes you feel light-headed, dizzy or drowsy or cause blurred vision, do not drive.

Alcohol

Avoid drinking alcohol. It may increase your risk of stomach bleeding and liver diseases.

Other General Warnings

Talk to your doctor if

If you have high cholesterol
If you have liver, kidney or heart disease
If you have any heart-related problems
If you have diabetes
If you have asthma

Mode of Action

How Does It Work?

Piroxicam decreases the inflammatory reaction by blocking the release of specific chemical mediators, which are responsible for pain and swelling, thereby reducing the pain, swelling, and other symptoms.

Interactions

Interactions with other medicines

Methotrexate
Blood thinner like Warfarin
Heart or blood pressure medication
Diuretics
Lithium
Steroid medicines

Interactions with food items

No specific interactions with food have been reported yet. Drink plenty of liquids to prevent dehydration.

Dietary Restrictions

No information is available on dietary restrictions while you are taking this medicine, consult your doctor or pharmacist for further details.

Dosage

Overdose

Symptoms of overdose can be lethargy, drowsiness, nausea, vomiting, stomach pain, blood in cough/vomit or stools, etc. Rise in blood pressure, kidney failure, difficulty in breathing and coma. If you happen to take an overdose of the medicine, seek emergency medical care immediately.

Missed a Dose

Do not take a double dose if you have missed the dose; take the next dose as soon as you remember.

Frequently Asked Questions (FAQs)

Piroxicam should be taken in the exact dose as advised by the physicianThe liquid medicine should be measured in a measuring device and then consumed. It shouldn’t be taken on approximate measurementsShake the oral suspension before every useDo not take more than the recommended dose of PiroxicamOverdose of Piroxicam can cause serious problems

Inform the doctor about your detailed medical and surgical historyInform your physician if you have any of the following conditions-Liver diseaseHeart diseaseHistory of heart attack or strokeHistory of stomach ulcers or stomach and intestinal bleedingAsthmaKidney diseaseIf you are pregnant, lactating or planning a pregnancyInform the physician about all the medicines that you are takingPiroxicam can have adverse effects when taken along with other medicines

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