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Pioglitazone

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Molecule Summary

Uses
Type 2 diabetes mellitus
Therapy
Anti-Diabetic
Side Effects
Headache, dizziness, numbness, weight gain, blurred vision
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Molecule Description

Pioglitazone is an anti-diabetic medicine. It is effective in improving blood sugar levels in patients with type 2 diabetes mellitus. While taking this medicine, you should be mindful of your diet and also exercise regularly. It should be taken as directed by your doctor, in the doses and duration prescribed. It can be taken with or without food. Before using this medicine, inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding, and provide your detailed medical history. Your doctor may frequently ask you to monitor your blood sugar levels while undergoing treatment with Pioglitazone.

Uses

Pioglitazone is used in type 2 diabetes mellitus patients to improve their blood sugar levels, along with diet and exercise.

Contraindications

When should one not use Pioglitazone

  • If you are allergic to Pioglitazone or any other ingredient of this medicine.
  • If you have diabetic ketoacidosis (uncontrolled diabetes along with nausea, vomiting, diarrhoea, rapid weight loss).
  • If you are suffering from any heart problems like heart failure.
  • If you have any problems with your liver.
  • If you ever had or have bladder cancer.
  • If you notice blood in your urine and your doctor is not aware of it.

Side effects

Common side effects of this drug are:

  • Headache
  • Dizziness
  • Respiratory tract infection like cough, sneezing, runny nose, sore throat
  • Weight gain
  • Numbness
  • Abnormal or blurred vision

Precautions and Warnings

Pregnancy

Pregnancy

Pioglitazone should not be used during pregnancy as there is limited information about its safety during pregnancy. Please consult your doctor if you are pregnant or think you may be pregnant or are planning to have a baby before starting this medicine.

Breast Feeding

Breast Feeding

You should not use this medicine while breastfeeding as it is unknown if Pioglitazone passes into breastmilk. Please consult your doctor before using this medicine.

Driving

Driving

Pioglitazone may blur your vision and make you feel dizzy, you should avoid driving if you do not feel well or are unable to be alert.

Alcohol

Alcohol

You should avoid consuming alcohol while on treatment with Pioglitazone.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You suffer from any liver disease.
  • You are suffering from any heart problem like irregular heartbeat, heart failure.
  • You are suffering from a certain type of diabetic eye disease called macular oedema.
  • You notice any type of swelling or have fluid retention, as Pioglitazone may worsen your condition.
  • You have cysts on your ovaries.
  • Pioglitazone may increase the risk of bone fractures.
  • When taking this medicine along with other antidiabetic medicines, you may experience episodes of low blood sugar. Always carry sugar or a bar of chocolate. Do not use sugar-free products during such episodes.
  • Pioglitazone is not recommended in patients below 18 years of age.

Mode of Action

How Does It Work?

Pioglitazone works by helping the body make better use of the insulin it produces.

Interactions

Interactions with other medicines

  • Pioglitazone may interact with other medicines, discuss with your doctor about all the medicines, supplements, or herbal preparations you are taking. Also, you should inform your doctor if you have a planned surgery or vaccination scheduled.
  • Pioglitazone should be used with caution along with gemfibrozil (used to lower blood cholesterol) and rifampicin (antibiotic) as it may alter its effects. Close monitoring of your blood sugar levels is necessary.

Interactions with food items

Pioglitazone can be taken with or without food. However, taking it at a consistent time each day is recommended for optimal blood sugar control.

Dosage

Overdose

Please seek immediate medical care if you experience any symptoms of low blood sugar (dizziness, shakiness, confusion, anxiety, palpitations, etc) or suspect an overdose with Pioglitazone.

Missed a Dose

If you missed any dose of Pioglitazone, take it as soon as you remember. However, if it's time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

Pioglitazone is used in type 2 diabetes mellitus patients to improve their blood sugar levels, along with diet and exercise.

Pioglitazone should be taken as directed by your doctor. Take it with a glass of water, with or without food. Do not cut, break or chew the medicine.

No, Pioglitazone is not recommended for use in patients less than 18 years old, as there is limited safety information available.

Pioglitazone is an anti-diabetic medicine.

Headache, dizziness, numbness, weight gain, blurred vision are a few common side effects of Pioglitazone, although not everyone gets them. Side effects often improve as your body gets used to the medicine.

You should take Pioglitazone exactly as advised by the doctor with or without food. But it is advised to take it at the same time each day for maximum benefits.

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