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Pimecrolimus

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Molecule Summary

Uses
Eczema (atopic dermatitis)
Therapy
Drugs For Atopic Dermatitis
Side Effects
Burning or a sensation of warmth at the application site, headache, common cold or stuffy nose, sore throat, cough, flu, fever
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Molecule Description

Pimecrolimus is a prescription medicine used on the skin (topical) to treat mild to moderate eczema (atopic dermatitis). It is for adults and children aged 2 years and older who do not have a weakened immune system. This medicine is used on the skin for short periods, and if needed, treatment may be repeated with breaks in between. This medicine is for use after other prescription medicines have not worked for you or if your doctor recommends that other prescription medicines should not be used. Limit your time in the sun during treatment with Pimecrolimus even when the medicine is not on your skin. If you need to be outdoors after applying it, wear loose-fitting clothing that protects the treated area from the sun. Ask your doctor about other types of sun protection you should use. Do not cover the skin being treated with bandages, dressings or wraps. You can wear normal clothing. Continuous long-term use of topical calcineurin inhibitors, including Pimecrolimus, in any age group should be avoided, and application limited to areas of involvement with eczema. Pimecrolimus is for use on the skin only. Do not get the medicine in your eyes, nose, mouth, vagina, or rectum (mucous membranes). If you get the medicine in any of these areas, burning or irritation can happen. Wipe off the medicine from the affected area, then rinse the area thoroughly with cold water.

Uses

Pimecrolimus is used for the treatment of mild to moderate eczema (atopic dermatitis) in patients aged 2 years and above.

Contraindications

When should one not use Pimecrolimus

  • If you are allergic to pimecrolimus or any other ingredients of this medicine.
  • If you are an immunocompromised patient and on systemic immunosuppressive medications.
  • If you have malignant or pre-malignant skin conditions, these can present as dermatitis.
  • If you are a patient with Netherton's syndrome or skin diseases that have the potential for increased systemic absorption.
  • If you have bacterial and viral skin infections.
  • If you are using sun lamps, tanning beds, or getting treatment with ultraviolet light therapy during treatment with Pimecrolimus.

Side effects

Common side effects of this drug are:

  • Burning or a sensation of warmth at the application site
  • Headache
  • Common cold or stuffy nose, sore throat
  • Cough
  • Flu (influenza)
  • Fever

Precautions and Warnings

Pregnancy

Pregnancy

Pimecrolimus should only be used during pregnancy if prescribed by a doctor. If prescribed, avoid using it on larger skin areas for an extended period.

Driving

Driving

Pimecrolimus is a topical medicine and may not affect the driving ability or ability to handle machinery.

Alcohol

Alcohol

No information is available on interactions of this medicine when taken with alcohol. Consult your doctor or pharmacist for further information.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You see no visible improvement, discontinue use and consult a medical professional.
  • Your eyes and mouth should not come into contact with this medicine, as it is intended for topical application only.
  • You are a pregnant or nursing woman.
  • You are a child less than 2 years of age.

Mode of Action

How Does It Work?

Pimecrolimus helps soothe inflammation in atopic dermatitis (a type of eczema). It does this by targeting small cells in your skin called T-cells, which play a significant role in causing redness and itchiness. Pimecrolimus works by essentially "turning off" these T-cells, preventing them from becoming overactive. It also helps reduce the release of substances that cause inflammation from other skin cells, resulting in less irritation and discomfort.

Interactions

Interactions with other medicines

  • Since Pimecrolimus is intended for external use on the skin, it is less likely to interact with other medications. However, it is always advisable to consult your doctor if you are taking other medications to treat other health conditions.
  • Medicines such as erythromycin, itraconazole, ketoconazole, fluconazole, calcium channel blockers, and cimetidine should be used with caution.

Dosage

Overdose

As Pimecrolimus is meant for external application, instances of overdose are unlikely. However, in the event of accidental ingestion, contact your doctor immediately or visit the nearest hospital. If you have applied an excess amount, please remove the surplus medicine with tissue or cotton.

Missed a Dose

If you have missed applying Pimecrolimus, apply it as soon as possible. Do not overapply this medicine to compensate for the missed application.

Frequently Asked Questions (FAQs)

No, Pimecrolimus is a prescription medication and should only be used under the supervision of a qualified healthcare professional, such as a dermatologist. Self-medicating with prescription drugs can lead to improper use, unexpected side effects, or worsening of your condition. A dermatologist can assess your specific skin needs, determine whether Pimecrolimus is appropriate for you, and provide the correct dosage and usage instructions to ensure safe and effective treatment. Always consult a healthcare provider before starting or changing any medication regimen.

Avoid using any cosmetic products while applying this medicine, as it may irritate the skin. It might also affect the activity of the medication.

The dose and frequency of applying this medicine will be decided by the doctor depending on the severity of the skin condition. Do not apply more than recommended.

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