Oxcarbazepine
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Molecule Description
Oxcarbazepine is an oral medicine used to treat a specific type of seizure, called partial seizure, in people who have epilepsy. It is an anticonvulsant or an antiepileptic medicine.
Uses
- Treat partial and complex partial seizures in patients with epilepsy
- Treatment of bipolar disorder (acts as a mood-stabilizing agent)
- Diabetic Neuropathic pain
- Neuralgia/ neuropathy
Contraindications
When should one not use Oxcarbazepine
- If known allergic to the Oxcarbazepine
- Patients with a history of atrioventricular block
Side effects
Common side effects of this drug are:
- Change in vision
- Change in walking or balance
- Clumsiness or unsteadiness
- Cough, fever, sneezing or sore throat
- Crying
- Dizziness
- Double vision
- False sense of well-being
- Feeling of constant movement of self or surroundings
- Mental depression
- Sensation of spinning
- Uncontrolled back-and-forth or rolling eye movements
- Hyponatremia (low sodium levels)
- Due to low sodium levels in the blood include: frequent seizures, trouble in swallowing and breathing, severe muscle pain, unusual bruising or bleeding, panic attack, feeling agitated or restless
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- If you have kidney disease
- If you have ever had an allergic reaction to Carbamazepine
- Birth control pills may not work while you are using Oxcarbazepine. To avoid pregnancy, use another form of birth control. Other types include condoms, a diaphragm or contraceptive foam or jelly
Mode of Action
How Does It Work?
This medicine stabilizes neuronal membranes by blocking Na+ channels and slows down the abnormal nerve impulses in the brain and thus helps treat epilepsy.
Interactions
Interactions with other medicines
- Anti-cancer medicines like Ibrutinib
- Antianginal like Ranolazine
- HIV medications like Tenofavir
- Hepatitis C medicine like Ritonavir
- Phenytoin, Phenobarbital, Carbamazepine, etc
Dietary Restrictions
Unless your doctor tells you otherwise, continue your regular diet.
Dosage
Overdose
Call immediately to the doctor if you suspect an overdose. Symptoms of overdose are low levels of sodium in the blood, anger, agitation, being confused, drowsiness or sleepiness, dizziness, feeling sick (nausea), being sick (vomiting), tiredness, changes to your heart rhythm (fast, irregular heartbeat), shaking, seizures/ convulsions, headache, coma, loss of consciousness, uncontrolled twitching or jerking, double or blurred vision, narrowing of the pupil, low blood pressure, shortness of breath, an abnormal degree of muscular or bodily activity, lack of coordination of movements and uncontrolled eye movements.
Missed a Dose
Take the missed dose as early as you remember. Skip the missed dose if it is almost time for your subsequent scheduled dose. Do not take extra medicine to compensate for the missed dose.
Frequently Asked Questions (FAQs)
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