Nimodipine
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Molecule Description
Nimodipine is a calcium channel blocking agent which is used to decrease problems caused due to a specific type of bleeding in the brain.
Uses
To prevent damage caused due to lack of blood flow to the brain.
Contraindications
When should one not use Nimodipine
- If you are getting Nimodipine solution through a drip
- If you are taking Rifampicin (an antibiotic), Phenobarbital, Phenytoin or Carbamazepine
- Allergic to this medicine
- History of recent heart attack
Side effects
Common side effects of this drug are:
- Low blood pressure
- Chest pain or discomfort
- Difficulty in breathing
- Irregular heartbeat or pulse
- Lightheadedness
- Sweating
- Swelling
- Rashes
- Stomach problems
- Vision problems
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have suffered any head injury
- You are taking any antibiotics
- You have liver disease or low blood pressure
Mode of Action
How Does It Work?
Our body naturally responds to bleeding by narrowing the blood vessels to slow blood flow. However, when the bleeding is in the brain, reduction in blood flow causes more damage to the brain. Nimodipine is said to work by relaxing narrowed blood vessels in the brain near the area of bleeding so that blood can flow more easily. This mechanism reduces brain damage.
Interactions
Interactions with other medicines
- Medicine for high blood pressure such as Propranolol and Metoprolol, Benazepril and Enalapril, Diltiazem, Verapamil, etc.
- Antibiotics (e.g. Clarithromycin, Telithromycin), Rifampicin
- Some HIV medications (e.g. Delavirdine, Indinavir, Nelfinavir, Ritonavir, Saquinavir)
- Some antifungal medicine (e.g. Ketoconazole, Itraconazole, Voriconazole)
- Some antidepressants (e.g. Nefazodone)
- Some antiepileptic medicines (Sodium Valproate)
Interactions with food items
Never consume Nimodipine with grapefruit juice as it can increase the chances of side effects with this medicine.
Dietary Restrictions
Do not consume grapefruit or it’s juice when you are on this medication.
Dosage
Overdose
Symptoms of overdose may include disturbed orientation and balance of body, low blood pressure, chest pain, an unusually fast or slow heartbeat, slurred speech, coma. Seek emergency medical help if you think you have taken exceeded dose of this medicine.
Missed a Dose
Take the missed dose of medicine as soon as you remember. If it is nearly the time for your next dose, skip the missed dose and take the medicine at the next scheduled hour. Do not take an extra dose of medicine to compensate for the missed dose.
Frequently Asked Questions (FAQs)
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