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Melatonin+Alprazolam

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Molecule Summary

Uses
Panic disorders, Insomnia, Anxiety disorder
Therapy
Hypnotic
Side Effects
Confusion, Fatigue, Drowsiness, Headache, Dizziness, Dryness of mouth, Nausea, Vomiting
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Molecule Description

Melatonin+Alprazolam is useful in treating anxiety and panic disorders. Further, Melatonin+Alprazolam helps in Insomnia, which means the inability to sleep at night. Melatonin+Alprazolam is a combination of Alprazolam, a sedative medicine and Melatonin, a natural hormone responsible for controlling sleep patterns.

Uses

  • As per CDSCO, the combination medicine Melatonin+Alprazolam is used to treat chronic Insomnia and anxiety and panic disorder for short-term management.

Contraindications

When should one not use Melatonin+Alprazolam

  • If you had an allergic reaction to any of the components of this medicine.
  • If you are taking any other medicine which can increase eye pressure.
  • If you are taking any other sedative medications.
  • If you are diagnosed with autoimmune conditions like Rheumatoid Arthritis, Myasthenia Gravis, Multiple Sclerosis, Lupus, etc.
  • If you are taking antifungal medicines.

Side effects

Common side effects of this drug are:

  • Drowsiness
  • Headache
  • Confusion
  • Dizziness
  • Fatigue
  • Dryness of mouth
  • Nausea
  • Vomiting

Precautions and Warnings

Pregnancy

Pregnancy

It is better to avoid taking Melatonin+Alprazolam during pregnancy, as there is not enough research regarding safety in pregnant women. Kindly consult your doctor if you are pregnant or planning for pregnancy before taking this medicine.

Breast Feeding

Breast Feeding

Melatonin+Alprazolam passes through the breast milk in small amounts, and hence, it can make the baby sleepy. Kindly tell your doctor about your lactation status before starting this medicine.

Driving

Driving

Do not drive yourself after taking Melatonin+Alprazolam. Driving is not legal when you aren't sure of being in your complete capacity to focus and pay attention to driving.

Alcohol

Alcohol

Do not consume alcohol or smoke while taking Melatonin+Alprazolam, as it may interfere with the action of the medicine over the system and increase its abuse potential.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You suffer from any autoimmune diseases like Rheumatoid Arthritis, Myasthenia Gravis, Lupus, Multiple Sclerosis, etc. and kidney or liver diseases.
  • You are taking any Oral Contraceptive pills, Warfarin, Antihypertensive medicines, Antifungal medicines.
  • You are an alcoholic or smoker.
  • You want to reschedule the medicine dosage or if you are experiencing serious side effects.

Mode of Action

How Does It Work?

Melatonin+Alprazolam has two components; Alprazolam works by acting positively on a chemical messenger in the brain called GABA, which suppresses the excessive, persistent and abnormal activity of brain cells. This allows the person to sleep. Also, Melatonin is itself called sleep hormone as it regulates the sleep-wake cycle.

Interactions

Interactions with other medicines

  • Antidepressants like Fluvoxamine and Imipramine
  • Antihypertensive medicines
  • NSAIDs like Naproxen Diclofenac and Ibuprofen
  • Oestrogens used in Contraceptives and Hormone Replacement Therapy
  • Quinolones or Rifampicin (Antibiotics)
  • Herbal remedies for Insomnia, if taken along with Melatonin+Alprazolam, can increase the sedating effects. Other medicines like Tryptophan supplements, Zaleplon, Zolpidem, and Zopiclone can lead to deep sleep, resulting in difficulty waking up. You need to tell your doctor if you are taking blood thinners like Warfarin.

Interactions with food items

  • Caffeine-containing drinks like tea, cola, coffee shouldn't be consumed as they reduce this medicine's effectiveness.

Dosage

Overdose

Overdose of Melatonin+Alprazolam may cause poisoning or serious side-effects such as blurring of vision, vertigo, bleeding from any site, and fainting. It may also lead to breathing difficulty and coma. Immediately visit the nearest hospital in case of an overdose emergency.

Missed a Dose

In case you miss a dose, take it as soon as you realise this. If the next dose is due, skip the missed dose and start the next dose. Never take two doses in fewer intervals as this may lead to toxicity. Please reset your dosages by consulting your doctor if too many doses are missed.

Frequently Asked Questions (FAQs)

Melatonin+Alprazolam is known to raise sugar levels in the blood. In diabetics, it may lead to symptoms such as increased urination, increased thirst and salivation, along with feeling dizziness and blurred vision, which is suggestive of uncontrolled blood sugar. It is necessary to consult your doctor for regulating diabetes or keeping a diabetic chart for self-control of sugar levels at home.

Certain antihypertensives need to be avoided for hypertension when taking Melatonin+Alprazolam. Follow your doctor's advice for other medicines that need to be taken to control blood pressure and blood sugar.

Melatonin+Alprazolam contains Alprazolam. If used for a long duration, it may lead to hunger and binge eating episodes that may cause weight gain. It may also lead to prolonged sleep and decreased energy output, which may, in turn, cause weight gain.

Yes, Melatonin+Alprazolam belongs to a sedative group of medicine, it calms the anxiety and allows sleep, so it is habit-forming and may cause dependency if not taken as per dosage advised by your doctor. It is also advised not to stop it abruptly, as it may have a withdrawal phenomenon and recurrence of anxiety-related symptoms.

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