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Loteprednol Etabonate+Moxifloxacin

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Molecule Summary

Uses
Eye inflammation with infection
Therapy
Ocular Antibiotic And Steroid
Side Effects
Headache, dry eyes, burning
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Molecule Description

Loteprednol Etabonate+Moxifloxacin is an ocular antibiotic and steroid medication. It contains a combination of moxifloxacin and loteprednol as active substances. Loteprednol Etabonate+Moxifloxacin is used in the treatment of inflammation (redness, pain, swelling) of the eye after eye surgery which may be associated with a bacterial infection. It works by reducing inflammation and killing the infection-causing bacteria. Loteprednol Etabonate+Moxifloxacin is meant for ocular (eye) use and should be used externally only. Do not ingest this medicine. Avoid touching the dropper with your hands or with your eye. This eye drop should not be used in children under 18 years of age. Use Loteprednol Etabonate+Moxifloxacin exactly as recommended by your doctor. Do not use this medicine on your own.

Uses

Loteprednol Etabonate+Moxifloxacin is used to treat inflammation (redness, pain, swelling) of the eye after eye surgery which may be associated with a bacterial infection.

Contraindications

When should one not use Loteprednol Etabonate+Moxifloxacin

  • If you are allergic to moxifloxacin, loteprednol or any of the other ingredients of Loteprednol Etabonate+Moxifloxacin.
  • If you have a history of allergy to any other corticosteroid or quinolones. If you are not sure what these medicines are, please confirm with your doctor.
  • If you have eye diseases caused by viruses such as herpes simplex, vaccinia or varicella.
  • If you have eye diseases caused by mycobacterium or fungi.
  • If you are a breastfeeding woman.

Side effects

Common side effects of this drug are:

  • Dry eyes
  • Headache
  • Eye pain
  • Eye irritation
  • Burning

Precautions and Warnings

Pregnancy

Pregnancy

There is limited information on the effect of Loteprednol Etabonate+Moxifloxacin in pregnancy. This eye drop should be used in pregnant women only if recommended by your doctor.

Breast Feeding

Breast Feeding

Loteprednol Etabonate+Moxifloxacin is contraindicated for use in breastfeeding women.

Driving

Driving

Loteprednol Etabonate+Moxifloxacin may cause temporary blurring of vision. If you experience any such effects after using this medicine that may affect your ability to drive safely, it is advised to avoid driving.

Alcohol

Alcohol

There is limited information available on the interaction of alcohol with Loteprednol Etabonate+Moxifloxacin. Ask your doctor for advice on alcohol intake along with this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have a condition called glaucoma, with increased pressure in the eyes.
  • You experience blurred vision or other visual disturbances after using this medicine.
  • You experience an allergic reaction after using Loteprednol Etabonate+Moxifloxacin.
  • You develop pain, redness, itching or inflammation that worsens.
  • Your symptoms do not get better within two days.
  • You wear contact lenses.
  • You take medicines called fluoroquinolones, mainly if you are an elderly patient or if you are taking medicines called corticosteroids.

Mode of Action

How Does It Work?

  • Loteprednol Etabonate+Moxifloxacin contains a combination of moxifloxacin and loteprednol as active substances.
  • Moxifloxacin is an antibiotic that prevents certain chemicals in the bacteria that are essential for the proper maintenance and functioning of bacterial DNA (genetic material). The inhibition of these chemicals leads to the death of infection-causing bacteria.
  • Loteprednol is a corticosteroid that works by reducing inflammation by stopping the release of certain natural substances that cause swelling and pain.

Interactions

Interactions with other medicines

  • Since Loteprednol Etabonate+Moxifloxacin is to be used externally, it is less likely to interact with other medicines.
  • However, consult your doctor if you are taking other medicines to treat any other health conditions.
  • Particular care should be taken if you are taking medicines called anticholinergics (used to treat conditions like gastrointestinal and muscular spasms, strong/sudden need to urinate or asthma) or other eye drops for the treatment of increased pressure in the eye.
  • Medicines like ritonavir and cobicistat used for the treatment of HIV may increase the effect of Loteprednol Etabonate+Moxifloxacin.

Dosage

Overdose

As Loteprednol Etabonate+Moxifloxacin is meant for external application, cases of overdose are unlikely. However, upon accidental ingestion, contact your doctor immediately or visit the nearest hospital. If you have instilled an extra quantity of the eye drop than recommended, wipe out the excess medicine with a clean tissue or cotton.

Missed a Dose

If you have missed instilling a dose of Loteprednol Etabonate+Moxifloxacin, instil it as soon as possible. Do not over-use this medicine to compensate for the missed instillation.

Frequently Asked Questions (FAQs)

Loteprednol Etabonate+Moxifloxacin is used for the treatment of inflammation (redness, pain and swelling) of the eye after eye surgery which may be associated with a bacterial infection.

No, Loteprednol Etabonate+Moxifloxacin is contraindicated for use in breastfeeding women.

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