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Lafutidine

Molecule Description

Lafutidine reduces stomach acid production, which has a protective effect in patients with stomach and duodenal ulcers. It belongs to a class of medicines called ‘H2-receptor blockers’.

Uses of Lafutidine

  • Treatment of ulcers of the stomach and the small intestine (duodenum)
  • Conditions where the stomach lining is disrupted (gastric mucosal lesions)
  • Increased acidity when stomach acid flows back into the oesophagus (Gastroesophageal Reflux Disease or GERD)
  • To prevent inhalation or aspiration of food from the stomach or oesophagus into the lungs (aspiration pneumonia)

Contraindications of Lafutidine

When should one not use Lafutidine

Allergy to Lafutidine, or any ingredient of the medicine, or other medicines of the same class.

Side effects of Lafutidine

Common side effects of this drug are:

  • Constipation
  • High uric acid levels in the blood (hyperuricemia)
  • Feeling unreal things to be real (hallucinations)
  • Decreased hunger
  • Enlargement of breasts in men (gynaecomastia)
  • Liver problems (jaundice - yellowing of the skin, and eyes)

Precautions and Warnings of Lafutidine

Pregnancy

Q:
Can I take Lafutidine during pregnancy?
A:
It is not ascertained if Lafutidine can harm the unborn baby or not. Hence this medicine is recommended in pregnant women only if other alternatives are not available.

Breast Feeding

Q:
Can I take Lafutidine while breastfeeding?
A:
Lafutidine is known to secrete in breast milk. It is advised not to use this medicine in breastfeeding mothers.

Driving

Q:
Can I drive if I have consumed Lafutidine?
A:
Lafutidine is not known to affect your driving ability.

Alcohol

Q:
Can I consume alcohol with Lafutidine?
A:
Alcohol should not be consumed in cases of stomach ulcers and intestines or acid reflux disease or in patients who are at risk for aspiration pneumonia (aspire food contents from stomach and oesophagus into the lungs).

Other General Warnings

Talk to your doctor if
  • You have kidney or liver disease
  • Caution is advised if you have any bleeding disorders

Mode of Action of Lafutidine

How Does It Work?

Lafutidine blocks specific receptors (proteins) on the lining of the stomach that stimulate acid production and also increases the secretion of the protective layer of the stomach lining called mucin. By doing so, it decreases stomach acid production and helps in healing the ulcers of the stomach and small intestine.
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Interactions of Lafutidine

Interactions with other medicines

  • Data is not available
  • Inform the physician about all the medicines that you are taking including prescription, non-prescription or herbal medcines

Interactions with food items

Lafutidine should be taken at least one hour after the meals.

Dietary Restrictions of Lafutidine

Follow a healthy diet. Avoid spicy and oily food.

Dosage of Lafutidine

Overdose

Accidental or unintentional overdose of Lafutidine may not be harmful. But in the presence of symptoms such as constipation, hallucinations, reduced hunger, yellowing of eyes or skin, consult your doctor.
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Missed a Dose

  • Take the missed dose as soon as you remember
  • If your next dose is near, skip the missed dose and continue with the next dose as per schedule
  • Do not take a higher or double dose to make up for the missed dose
  • Ideally, there should be a 12-hour gap between two doses

Content Details

WRITTEN BY
REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

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Q: Is Lafutidine effective in reducing stomach acid?

  • Lafutidine is a potent medicine to reduce stomach acid production
  • It blocks the histamine receptor proteins present on the lining of the stomach whose primary function is to stimulate acid secretion
  • It also promotes excretion of the thick mucus layer that protects the lining of the stomach
  • Thus, Lafutidine prevents damage to stomach lining and also helps in healing, especially those ulcers caused due to use of pain killers
  • Its action is long-lasting, safety profile is good and has demonstrated better efficacy than other similar medicines in clinical trials

Q: Is there anything else I need to know before using Lafutidine?

  • The dosage, duration, and frequency of Lafutidine varies according to the condition and hence should be taken under medical supervision
  • Do not self-adjust the dose or stop using this medication without the knowledge of your doctor
  • Lafutidine is taken once or twice a day, usually after breakfast and after dinner
  • Patients undergoing hemodialysis should start on a lower dose
  • Caution is advised while using Lafutidien as some severe side effects such as allergic reactions, kidney or heart problems that are not listed above can occur with this medicine
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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