Iloperidone

Molecule Description

Iloperidone belongs to ‘atypical antipsychotics’ class of medicines.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Iloperidone

It is used to treat recent mental disorders characterized by mood and behavioral changes like feeling things that are unreal or did not happen (acute schizophrenia).

Contraindications of Iloperidone

When should one not use Iloperidone

If you have an allergy to Iloperidone or any of its ingredients
If you have any psychiatric illness due to age-related brain problems such as memory, thinking or language problems (dementia related psychosis)
If you have severe liver problems

Side effects of Iloperidone

Common side effects of this drug are:

Drowsiness
Dry mouth, dizziness, fatigue, running or stuffy nose
Feeling sleepy (lethargy), fast heartbeats (tachycardia), weight gain
Prolonged and slow heart rate (prolonged QTC interval) which can be fatal
Dizziness, falling or fainting when getting up from sitting or lying position (orthostatic hypotension)
High blood sugar and cholesterol levels which may increase the risk of heart disease and brain stroke
Very high fever, elevated heart rate and blood pressure, tremors, stiff muscles and confusion – neuroleptic malignant syndrome (rare but serious)
Severe allergic reactions including swelling of face, lips and throat causing swallowing and breathing problems, with or without rashes, itching, skin peeling and blisters (rare but serious)

Precautions and Warnings of Iloperidone

Pregnancy

Can I take Iloperidone during pregnancy?

Iloperidone should be used with caution during the first six months of pregnancy (2 trimesters) only if other alternatives are not available. It should be avoided during the 3rd trimester (or last three months) of pregnancy.

Breast Feeding

Can I take Iloperidone while breastfeeding?

It is unknown if Iloperidone is secreted in breast milk. Still, because it has the potential to cause unwanted effects in the baby, it is recommended to avoid this medicine in breastfeeding mothers.

Driving

Can I drive if I have consumed Iloperidone?

This medicine may cause problems such as dizziness or drowsiness, reduced alertness, thinking learning and movement problems. You are advised to drive if you experience no such symptoms.

Alcohol

Can I consume alcohol with Iloperidone?

Avoid alcohol as it can increase the side effects due to Iloperidone.

Other General Warnings

Talk to your doctor if

Inform your doctor if you develop any of the following:
Increase in thirst, urination or hunger (due to high blood sugars)
Low white blood cell counts
Breast pain and discharge, irregular menstrual periods or impotence in males (due to increased levels of prolactin hormone)
Reduced body temperature
Suicidal thoughts
History of seizures (fits)
Prolonged erection (priapism)
Uncontrolled movements of the face, tongue or other parts of the body (tardive dyskinesia) which may become permanent. You are advised to inform the doctor if you experience any such symptoms
You should tell your doctor before surgery regarding all the products you use (including prescription medicines, non-prescription medicines and herbal products)

Mode of Action of Iloperidone

How Does It Work?

Iloperidone acts by reducing or suppressing the activity of the brain and thus calming the person. It does this by blocking the actions of substances that transmit signals in the brain (neurotransmitt...

Interactions of Iloperidone

Interactions with other medicines

Ketoconazole (antifungal)
Certain antidepressants (Fluoxetine, Paroxetine)
Few medicines which may increase the risk of irregular heartbeat (3 Procainamide, Quinidine, Sotalol)
Certain antibiotics (such as Gatifloxacin, Moxifloxacin, Pentamidine)
Antianxiety medicines (Prochlorperazine, Chlorpromazine, Trifluoperazine, Perphenazine, etc.)
Methadone (opioid pain killer)

Interactions with food items

Iloperidone can be taken before or after meals.

Dosage of Iloperidone

Overdose

Take Iloperidone in the exact dose as prescribed by your doctor. Inform the doctor in case of any overdose symptoms such as drowsiness, rapid heartbeat or feeling lightheaded.

Missed a Dose

Take the missed dose as early as you remember. If it is time for the next dose (less than 6 hours), skip the missed dose and continue your regular dosing schedule. Do not take a higher or a double dos...

Content Details

WRITTEN BY

Dr. Nikita Toshi

BDS (Bachelor of Dental Surgery)

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: Is there anything else I need to know before taking Iloperidone?

Iloperidone may affect your heart rhythm so inform the doctor if you experience any irregular, prolonged, forceful heartbeats or abnormal heart rhythms
There could be potential weight gain due to Iloperidone as is the case with most of the medicines used to treat psychiatric illness
This medicine may also cause you to fall and increase the risk of fractures
Iloperidone can cause some severe side effects like prolonged and slow heart beats (prolonged QTC interval), irregular heartbeats and rhythms, uncontrollable movements of the face and tongue, swallowi...
Read more
You are advised to be cautious if you or anyone close to you is taking this medicine and report any observed side effects to the doctor promptly
Iloperidone should not be used in patients less than 18 years of age and patients with liver disease

Q: Is Iloperidone an effective medicine?

Iloperidone is believed to be an effective medicine to treat schizophrenia and is widely used with success. It works well and is better tolerated (lesser side effects) than most of the medicines used ...
Read more
This medicine has to be started at low doses and the required dose should be reached gradually. This is because Iloperidone may cause dizziness when standing up from sitting or lying position (orthost...
Read more
Due to this reason, it may take time for you to experience any relief of symptoms (like 1-2 weeks)
Most of the side effects of Iloperidone occur when high doses are used and this medicine is usually safe at lower doses

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय: “बिना मशरूम के खाना बिना बारिश के दिन जैसा होता है”। मशरूम या अगरिकस बिस्पोरस न तो सब्ज़ी है और न ही फल, बल्कि यह खाई जाने वाली एक फंगस है। बाजार में इसकी अलग-अलग किस्में (ताजा व सूखा) उपलब्ध हैं; जिसमे ओएस्टर , पोर्सिनी और बटन सबसे आम किस्में हैं। आमतौर पर, मशरूम

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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