Gemfibrozil

Molecule Description

Gemfibrozil is used to treat high cholesterol and triglyceride levels in the bl

ood. High levels of cholesterol may result in blockage of arteries (atherosclerosis), which leads to heart diseases.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Gemfibrozil

To treat high cholesterol levels and triglyceride levels
To reduce the risk of stroke, heart attack and other heart problems

Contraindications of Gemfibrozil

When should one not use Gemfibrozil

Allergic to Gemfibrozil or any of the other ingredients of it
You have liver, kidney or gall bladder disease
You have a history of gall stones, photoallergy
You are currently taking any medicine called Repaglinide

Side effects of Gemfibrozil

Common side effects of this drug are:

Indigestion
Spinning (vertigo)
Headache, stomach pain
Diarrhoea, constipation

Precautions and Warnings of Gemfibrozil

Pregnancy

Can I take Gemfibrozil during pregnancy?

The effect of Gemfibrozil on the fetus is not known, consult your doctor if you are pregnant, your doctor will tell you on the use of this medicine after assessing the benefits over risks.

Breast Feeding

Can I take Gemfibrozil while breastfeeding?

It is not safe to use this medicine during breastfeeding.

Driving

Can I drive if I have consumed Gemfibrozil?

This medicine may sometimes cause dizziness or tiredness. You may drive if you feel comfortable.

Alcohol

Can I consume alcohol with Gemfibrozil?

Alcohol may interfere with treatment. It is better to avoid drinking alcohol while taking this medicine.

Other General Warnings

Talk to your doctor if

You have a history of muscle breakdown (rhabdomyolysis)
Kidney impairment
Gall bladder diseases
Liver disorders
Excessive use of alcohol
Diabetes

Mode of Action of Gemfibrozil

How Does It Work?

Gemfibrozil reduces cholesterol levels by increasing the activity of an enzyme, which breaks down triglycerides.

Interactions of Gemfibrozil

Interactions with other medicines

Colchicine (medicine for gout)
Dasabuvir (treatment of Hepatitis C)
Paclitaxel (treatment for cancer)
Montelukast (treatment for asthma)
Repaglinide, Pioglitazone (Anti-diabetic medication)
Cholesterol-lowering drugs- ‘statins’
Warfarin (blood thinner)
Loperamide (treatment of diarrhea)
Enzalutamide (medicine for prostate cancer)
Selexipag (medicine for the treatment of pulmonary hypertension)

Interactions with food items

No interactions with food have been observed yet.

Dietary Restrictions of Gemfibrozil

Stick to a low-fat diet. Avoid oily food.

Dosage of Gemfibrozil

Overdose

Abdominal cramps, diarrhea, nausea, vomiting, joint, and muscle pain are some of the effects of overdose. Call your doctor immediately in case you suspect an overdose.

Missed a Dose

Take the missed dose as early as you remember. Skip the missed dose if it’s already the time for next scheduled dose. Do not take extra medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What should I discuss with my healthcare expert before taking Gemfibrozil?

A: You must inform your doctor if you are suffering from any kidney, liver diseases or gall stones or if you are taking blood thinners (like Warfarin) if you are already taking any statin cholesterol medicine.

Q: What else should I keep in mind while I take Gemfibrozil?

A: Follow a healthy diet involving less fat and cholesterol, weight control program, and exercise along with Gemfibrozil for optimum benefits.

References

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Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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