Gemcitabine

Molecule Description

Gemcitabine belongs to a group of medicines called anticancer drugs.

Uses

Contraindications

Side effects

Precautions and Warnings

Uses of Gemcitabine

It is used in the treatment of many cancers like non-small cell lung cancer (NSCLC), either alone or along with Cisplatin
Pancreatic cancer
Breast cancer, along with Paclitaxel
Ovarian cancer, along with Carboplatin
Bladder cancer, along with Cisplatin

Contraindications of Gemcitabine

When should one not use Gemcitabine

If you are allergic to Gemcitabine
If you are breastfeeding

Side effects of Gemcitabine

Common side effects of this drug are:

Drowsiness
Swelling and redness at the injection site
Hair loss and eventually baldness
Skin rash
Liver damage
Constipation
Pale skin
Diarrhea
Nausea
Breathing in difficulty
Chest pain
Low white blood cell count
Weakness in the body
Chills
Infections

Precautions and Warnings of Gemcitabine

Pregnancy

Can I take Gemcitabine during pregnancy?

If you are pregnant or planning a pregnancy, it is advisable to find a viable alternative on consultation with your doctor.

Breast Feeding

Can I take Gemcitabine while breastfeeding?

Breastfeeding is not recommended when taking this medication, and if you are breastfeeding before starting the treatment, consultation with a doctor is recommended to find suitable substitutes.

Driving

Can I drive if I have consumed Gemcitabine?

Gemcitabine is known to cause dizziness and drowsiness; hence, you should avoid performing any activity that requires concentration. The medication also causes tiredness, thus driving is not recommended after you take this medication.

Alcohol

Can I consume alcohol with Gemcitabine?

It is advisable not to consume alcohol, but a consultation with a doctor will clarify whether the consumption of alcohol is harmful.

Other General Warnings

Talk to your doctor if

You may experience swelling, weight gain, difficulty in breathing after taking this medicine
Kidney disease
Liver disease
Do not take any medication that contains Aspirin
Headache with confusion and convulsions
If you are already receiving radiation therapy
You should contact your doctor, regardless of any kind of medication you might be consuming
You should not take any vaccine, without a doctor's approval; while Gemcitabine is being given

Mode of Action of Gemcitabine

How Does It Work?

The medicine is hydrophilic (attracted to water) in nature and kill cells, which are dividing continuously, including cancer cells.

Interactions of Gemcitabine

Interactions with other medicines

Gemcitabine is known to have severe interactions with Clozapine and any live vaccine. It is also known to have moderate reactions with Warfarin and Fluoroquinolone antibiotics.

Interactions with food items

There are no specific interactions with foods. However, you should eat foods that are clean and avoid unpasteurized food items.

Dietary Restrictions of Gemcitabine

You should avoid foods that might be contaminated or unwashed such as fruits and vegetables, unpasteurized juices and milk, raw and undercooked meat, and other fresh produce.

Dosage of Gemcitabine

Overdose

If you face any difficulty in breathing and become unconscious, seek medical help immediately.

Missed a Dose

If you missed any dose of medicine, take it as soon as you remember. If it is time for your next dose, then continue with it. Don’t take a double dose of medicine to compensate for the missed dose.

Content Details

WRITTEN BY

Dr. Ravi Kakarla

MBBS, MBA

REVIEWED BY

Dr. Ritu Budania

MBBS, MD (Pharmacology)

Frequently Asked Questions (FAQs)

Q: What happens if I get cuts or bruises while on Gemcitabine medication?

A: Gemcitabine increases your susceptibility to infections, which is why you should cover it up immediately and get a look at it. Avoid using sharp objects while under Gemcitabine medication.

Q: What should I do if I feel body pains and severe headaches?

A: This is a rare phenomenon, but if in the chance you start speaking with a lot of drag and stutter, complains of arm and body pain, rush to a doctor immediately.

Q: Will I lose my hair?

A: Yes, since Gemcitabine is a part of chemotherapy, there will be hair loss. Once you complete your treatment, your hair will grow back.

References

Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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परिचय वानस्पतिक नाम एम्ब्लिका ऑफिसिनैलिस आमतौर पर आंवला को इंडियन गूजबेरी (भारतीय करौंदा) कहा जाता है। इन पेड़ों की बेरी को इनके औषधीय गुणों के कारण औषधीय फार्मूलेशन में प्रयुक्त किया जाता है। आंवला के पेड़ पर छोटी बेरीज़ होती हैं जो गोल और पीले-हरे रंग की होती है। इसके कई स्वास्थ्य फ़ायदों के कारण

केला (Banana in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: “एक दिन में एक केला (बनाना) खाने से मेरा एंडोर्फिन लेवल बना रहता है।” बनाना (मूसा प्रजाति) या केला एक लंबा, पीला फल है जो वास्तव में एक बेरी है। यह मुसासी (मुसासेई) परिवार से संबंधित हैं और इसमें मूसा एक्यूमिनाटा, मूसा बालबिसियाना आदि किस्में शामिल हैं। यह दक्षिणी एशिया के उष्णकटिबंधीय क्षेत्रों (ट्रॉपिकल

सौंफ (Fennel Seed in Hindi) : उपयोग, लाभ और न्यूट्रिशनल वैल्यू

परिचय: सौंफ (फेनल सीड) का वैज्ञानिक नाम फीनीकुलम वल्गारे है और यह एपोकिनेसी परिवार से संबंधित एक सुगंधित पौधा है।1 सौंफ (फेनल सीड) की एक अलग आकृति, आकार और रंग होता है; यह लंबी, पतली होती है और हल्के हरे या भूरे रंग की होती है। सौंफ (फेनल सीड) का पौधा इसके बीजों, पत्तियों और

ड्रैगन फ्रूट (Dragonfruit in Hindi): उपयोग, लाभ और न्यूट्रिशनल वैल्यू

ड्रैगन फ्रूट कैक्टस प्रजाति का फल होता है जिसके स्वास्थ्य से जुड़े कई लाभ होते हैं जैसे कि रक्त शर्करा (ब्लड शुगर) के जोखिम को कम करना, पाचन (डाइजेशन) में मदद करना आदि। यह एक ड्रैगन की तरह दिखता है और इस वजह से इसका यह नाम पड़ा। अब आप सोच रहे होंगे कि इस

तेजपत्ता (Bay Leaves in Hindi)– उपयोग, फायदे और न्यूट्रिशनल वैल्यू

परिचय तेजपत्ता सिनामोमम तमाला नामक पौधे की सूखी पत्तियां होती हैं। यह सिनामोमम वंश के लौरेसी परिवार का पौधा होता है जिसकी 270 प्रजातियां हैं और प्रमाणिक रूप से ये सभी एशिया और ऑस्ट्रेलिया में पाई जाती हैं। तेजपत्ता को भारतीय बे-लीफ़ भी कहा जाता है जो छोटे सदाबहार या बारहमासी वृक्ष पर होते हैं

नाशपाती (Pear in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू आदि!

परिचय: नाशपाती का वैज्ञानिक नाम पायरस कमिनिस एल है। यह रोज़ेसी फ़ैमिली से संबंधित है। नाशपाती को सेब के बाद सबसे ज्यादा पौष्टिक फल माना जाता है। यह विटामिन आहार फाइबर, एमिनो एसिड, एवं क्वेरसेटिन का बढ़िया स्रोत होता है। नाशपाती अपने मिठास, सुगंध, कुरकुरेपन और ख़ास खुशबू के लिए जाना जाता है। मूल रूप

सीए 125 टेस्ट (महिलाओं के लिए) (CA 125 Test (For Women) in Hindi): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: सीए 125 टेस्ट का इस्तेमाल शरीर में सीए 125 प्रोटीन के स्तर का पता लगाने के लिए किया जाता है, जो कैंसर का पता लगाने में मददगार साबित हो सकता है। नमूना प्रकार खून उपवास \ खाली पेट रहना जरूरी: नहीं उपनाम: कैंसर एंटीजन 125 टेस्ट, सीए-125 ट्यूमर मार्कर, सीए 125 ब्लड टेस्ट। सीए

सीरम इलेक्ट्रोलाइट्स (Serum Electrolytes): क्या है, खर्च, नॉर्मल रेंज, कैसे होता है, क्यों और कब

विवरण: एक सीरम इलेक्ट्रोलाइट परीक्षण आपके खून में मौजूद इलेक्ट्रोलाइट्स के स्तर को मापने की एक विधि है। इससे किडनी या दिल की समस्याओं जैसी कई बीमारियों का निदान करने में मदद मिल सकती है। आपको यह परीक्षण कितनी बार लेना चाहिए? कोई विशिष्ट आवृत्ति नहीं है। डॉक्टर आमतौर पर सीरम इलेक्ट्रोलाइट परीक्षण को मेटाबोलिक

हींग (Asafoetida in Hindi): उपयोग, फ़ायदे, न्यूट्रिशनल वैल्यू और अन्य बातें!

परिचय दुनिया के बहुत से हिस्सों में, हींग (ऐसाफ़ेटिडा) को खाने का स्वाद बढ़ाने वाले तत्व के रूप में और विभिन्न प्रकार की बीमारियों का पारंपरिक रूप से उपचार करने के लिए किया जाता है। हींग (फ़ेरुला ऐसाफ़ेटिडा), एक ओलिओ-गम-रेज़िन है जो अंबेलीफेरा फ़ैमिली के फ़ेरुला पौधों के तनों में बनती है। फ़ेरुला के पौधे

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