Estrogen
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Molecule Summary
| Uses | Hormone Replacement Therapy (HRT) |
| Therapy | Hormone Replacement Therapy |
| Side Effects | Hairfall, depression, muscle cramps, weight variation, abnormal bleeding |
Medicines
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Molecule Description
Estrogen (conjugated oestrogens) is a type of medicine known as Hormone Replacement Therapy. It is used to treat menopausal symptoms such as hot flushes, sleep problems, irritability and depression in postmenopausal women. It can also be used to treat osteoporosis (bone loss and fragility) in postmenopausal women who are prone to fractures.
Estrogen works by imitating the actions of the natural hormone and is used to manage the symptoms of menstrual & gynaecological disorders due to imbalance in the hormonal levels.
Estrogen should be taken as directed by the doctor and in doses and duration as prescribed. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting this medicine.
Do not self-medicate with Estrogen and it is recommended to follow all the instructions given by your doctor before taking this medicine.
Uses
- Estrogen is used to treat menopausal symptoms such as hot flushes and sleep problems in postmenopausal women.
- Estrogen is used in the treatment of menstrual & gynaecological disorders due to hormonal imbalance.
- It is also used in preventing bone problems like osteoporosis during the post-menopausal stage.
Contraindications
When should one not use Estrogen
- If you are allergic to conjugated oestrogens or any other ingredient of this medicine.
- If you have or have had breast cancer, a blood clotting disorder, or a heart or liver-related problem.
- If you have a known history of womb cancer and womb related problems.
- If you have a known history of vaginal bleeding (unexplained).
- If you ever had a history of a blood clot in any of the organs or legs.
- If you are pregnant or breastfeeding.
Side effects
Common side effects of this drug are:
- Hair fall
- Depression
- Muscle cramps
- Abnormal bleeding
- Variation in weight
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have any kind of pre-existing health condition such as a history of blood clots, diabetes, gall stones, fits, hypertension, heart-related problem, liver or kidney disorder, weak immunity, headache or migraine, respiratory problem, hearing problem, etc.
- You have higher levels of fat in your blood. If you are unsure, discuss this with your doctor.
- You have a history or currently having low levels of calcium in the blood.
Mode of Action
How Does It Work?
Estrogen in this medicine acts similarly to the naturally present estrogen that works in normal conditions and helps in regulating the normal functions of the uterus. Thus, it helps in preventing the symptoms during the menopause stage like hot flushes, mood swings, etc.
Interactions
Interactions with other medicines
- Certain medicines may affect the way Estrogen works or this medicine itself can affect the action of other medicines taken at the same time.
- Inform your doctor about any other medicines, herbal preparations and supplements you are currently taking or might take to avoid any interaction with this combination of medicine.
- Especially, if you are taking medicines for treating fits, bacterial and fungal infections, Cushing syndrome, stomach ulcers, Anti-tuberculosis medicines, anti-HIV medicines, St. John's wort (herbal medicine for brain disorder), etc.
- Concomitant use of steroid medicines like dexamethasone with Estrogen should be avoided.
Interactions with food items
It is recommended to avoid grapefruit juice during the treatment with this medicine.
Dosage
Overdose
An overdose of Estrogen may lead to signs and symptoms of nausea, vomiting, dizziness, abdominal pain, drowsiness/ fatigue and withdrawal bleeding, etc. Seek urgent medical help if you experience any such symptoms or feel that you have taken too much of this medicine.
Missed a Dose
If you have missed taking a dose of Estrogen, then take it as soon as you remember. If it is almost time for your next dose, then skip the missed dose. Do not take a double dose to compensate for the missed one.
Frequently Asked Questions (FAQs)
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