Diclofenac

• To relieve pain, stiffness and swelling of the joints in conditions like rheumatoid arthritis, osteoarthritis, gout, ankylosing spondylitis.
• It helps in relieving pain following dental surgery, pain after an operation and surgical procedures, pain due to minor injury etc.

When should one not use Diclofenac

• If you are allergic to diclofenac.
• If you have or have had stomach or intestinal ulcers or bleeding problems in the gut.
• If you suffer from heart problems like a heart attack, stroke or heart failure.
• If you have developed allergic reactions or bowel problems after taking a painkiller in the past.
• If you have problems with the liver or kidneys.
• If you are pregnant, planning pregnancy or a woman of childbearing age not using contraceptive measures.

Common side effects of this drug are:

• Nausea
• Vomiting
• Stomach pain
• Diarrhoea
• Indigestion
• Constipation
• Headache
• Dizziness
• Heartburn

Other General Warnings

• You may experience problems with your heart, liver, or kidneys.
• You may suffer from stomach or intestinal diseases.
• You are above 60 years of age.
• You smoke and consume alcohol in excess or too often.
• You may suffer from a condition called porphyria.
• You may suffer from a blood or bleeding disorder.
• You may have lupus or a similar condition.
• You may have problems with circulation.
• You may have asthma, diabetes or high blood cholesterol.

How Does It Work?

Interactions with other medicines

• Diuretics may have reduced effectiveness or increase kidney-related side effects when taken with diclofenac.
• Blood thinners such as warfarin or acenocoumarol may increase the risk of bleeding.
• Medications for high blood pressure may become less effective.
• Diabetes medications may affect blood sugar control, requiring closer monitoring.
• Taking other pain relievers or NSAIDs together may increase the risk of stomach or kidney problems.
• Immunomodulators may increase the risk of infections or other side effects.
• Certain anti-infectives, such as some antibiotics or antivirals, may alter diclofenac levels or increase its side effects.
• Steroids, also known as corticosteroids, may increase the risk of stomach irritation, ulcers, or bleeding.
• Medications for heart conditions may raise the risk of cardiovascular side effects.
• Antacids may reduce absorption of diclofenac; follow your doctor’s instructions.
• Cholesterol-lowering medicines may affect how diclofenac is metabolised.
• Do not take diclofenac within 8–12 days after using mifepristone.
• Always inform your doctor about all medications, supplements, or herbal products you are taking to avoid interactions.