Deferoxamine

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NPPA
Regulated

Molecule Description

Deferoxamine is chelating agent that is used in iron poisoning. It is most effective when given as soon as possible after the iron is consumed.

Uses

It is used to treat sudden iron poisoning
It is used to remove excess of iron from blood that is accumulated due to frequent blood transfusions

Contraindications

When should one not use Deferoxamine

Renal diseases
Allergy to the substance

Side effects

Common side effects of this drug are:

Flushing
Severe itching, dizziness
Fast heartbeat
Fainting

Precautions and Warnings

Pregnancy

This medicine is not recommended for usage in pregnant women, unless necessary. A consultation with a doctor will determine the best course of action based on the severity of the case.

Breast Feeding

It is not recommended if you are nursing and may be advised to discontinue the medication or to discontinue breastfeeding.

Driving

You should consult your doctor if you will perform activities that require attention once you start medication.

Alcohol

The interaction with alcohol is unknown, and a consultation with the doctor is advised.

Other General Warnings

Talk to your doctor if

You have decreased calcium levels in the blood
Increased parathyroid hormone in blood - hyperparathyroidism

Mode of Action

How Does It Work?

This medicine acts by binding with iron present in the blood and enhancing its elimination through urine. It also speeds up the healing of any nerve damage due to excess iron.

Interactions

Interactions with other medicines

Prochlorperazine
Medicines for heart disease
Vitamin C

Interactions with food items

No information is available on interactions of Deferoxamine when taken with food, consult your doctor or pharmacist for further information.

Dosage

Overdose

Signs of overdose are hypotension, gastrointestinal disturbances, acute loss of vision, agitation, headache, bradycardia, and acute renal failure.

Missed a Dose

If you missed any dose of medicine, take it as soon as you remember. If it's time for your next dose, then skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of medicine to compensate for the missed one.

Frequently Asked Questions (FAQs)

The medicine was made legal and approved for usage in 1968 in the United States, but it is only FDA approved for the treatment of iron overdose or toxicity.

Yes, it is given to children to treat iron poisoning, but it should not be given to children under the age of three.

No, you should not partake in activities that require your full focus and attention, such as heavy lifting, driving, or working. This is because the medicine has side effects that can cause dizziness and blurred vision.