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Clopidogrel+Atorvastatin

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Molecule Summary

Uses
High cholesterol and prevent heart attack
Therapy
Anti-Platelet And Hypolipidemic Drugs
Side Effects
Nausea, indigestion, sleeplessness, joint or muscle pain, loose motions
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Molecule Description

Clopidogrel+Atorvastatin is a combination medicine containing atorvastatin and clopidogrel. It is used to lower the lipid or cholesterol in the blood along with a low-fat diet and lifestyle changes. It is also used to reduce the risk of blood clot formation thus aids in preventing a heart attack, stroke, etc. Atorvastatin works by lowering bad cholesterol levels thus reducing the risk of heart diseases and preventing strokes and heart attacks. Clopidogrel works by preventing platelets from sticking together and thus inhibiting blood clot formation. It helps in keeping the blood flow smoothly in your body. Nausea, indigestion, sleeplessness, joint pain or muscle pain are some of the side effects of using Clopidogrel+Atorvastatin.

Uses

  • To lower the lipid or cholesterol in the blood along with a low-fat diet and lifestyle changes.
  • To reduce the risk of blood clot formation thus aids in preventing a heart attack, stroke, etc.

Contraindications

When should one not use Clopidogrel+Atorvastatin

  • If you are allergic to atorvastatin, clopidogrel or any other ingredients of Clopidogrel+Atorvastatin.
  • If you have any liver disease.
  • If you have bleeding due to an ulcer in your bowel or bleeding in your brain.
  • If you are pregnant or may become pregnant.
  • If you are a lactating mother.

Side effects

Common side effects of this drug are:

  • Nausea
  • Indigestion
  • Sleeplessness
  • Joint or muscle pain
  • Loose motions
  • Constipation
  • Increased bleeding tendency

Precautions and Warnings

Pregnancy

Pregnancy

Components of this medicine can cause harm to unborn babies if taken by pregnant women. This medicine should not be taken by pregnant women.

Breast Feeding

Breast Feeding

It is not known whether components of this medicine pass into breast milk. This medicine should not be taken by a lactating mother.

Driving

Driving

Limited information is available for the effect of this medicine on driving. It is recommended to avoid driving if you experience dizziness or you are unable to stay alert.

Alcohol

Alcohol

Consuming alcohol while on this medicine can cause bleeding from the stomach or can cause liver problems. Avoid consuming alcohol while on this medicine.

Other General Warnings

Other General Warnings

Talk to your doctor if
  • You have liver or kidney disease.
  • You have muscle pain or muscle weakness after taking this medicine.
  • You have diabetes or any lung diseases.
  • You have a recent history of stroke.
  • You have any scheduled surgery.
  • You have a fever or your blood platelet level decreases after taking this medicine.

Mode of Action

How Does It Work?

  • Atorvastatin works by lowering bad cholesterol thus reduces the risk of heart diseases and prevents stroke and heart attacks.
  • Clopidogrel works by preventing platelets from sticking together and thus inhibiting blood clot formation. It helps in keeping the blood flow smoothly in your body.

Interactions

Interactions with other medicines

  • Concomitant use of Clopidogrel+Atorvastatin with other medicines such as Omeprazole, Esomeprazole, Fluoxetine, Fluconazole, Carbamazepine, Efavirenz can decrease the action of clopidogrel present in this medicine.
  • Concomitant use of Clopidogrel+Atorvastatin with other medicines such as Niacin, Cyclosporine, Clarithromycin, Gemfibrozil, Itraconazole or medicines from the protease inhibitor group of medicines can cause muscle problems.
  • Concomitant use of this medicine with medicines such as Ritonavir, Lopinavir, Indinavir, Ketoconazole, and Clarithromycin can increase the blood level of Atorvastatin.
  • Concomitant use of Clopidogrel+Atorvastatin with medicines such as Efavirenz, Rifampin can decrease the blood level of Atorvastatin.
  • Concomitant use of Clopidogrel+Atorvastatin with medicines from the NSAID group of medicines used in pain management can increase the risk of stomach or bowel bleeding.
  • Clopidogrel+Atorvastatin should be used cautiously with oral contraceptives.
  • Discuss with your doctor about any other medicines, herbal preparations and supplements you are taking currently to avoid any possible interactions.

Interactions with food items

Consumption of excessive grapefruit juice (more than 1.2 lit/ day) along with this medicine can increase the blood level of atorvastatin.

Dosage

Overdose

Symptoms of an overdose include increased bleeding tendency. If you have taken too much of this medicine then contact your doctor or reach out to the nearest hospital immediately.

Missed a Dose

If you have missed taking any dose of Clopidogrel+Atorvastatin then take it as soon as you remember. If it's already time for the next dose then skip the missed dose and follow the regular dosing schedule.

Frequently Asked Questions (FAQs)

Clopidogrel+Atorvastatin is a combination of two active components, clopidogrel and atorvastatin (acts as a cholesterol-lowering agent). Clopidogrel acts as a blood-thinning agent, which prevents the platelets from sticking together and decreases the formation of harmful blood clots.

You can take Clopidogrel+Atorvastatin with or without food, as advised by the doctor. But it is advised to take it at the same time every day for better results.

The contents present in Clopidogrel+Atorvastatin are atorvastatin and clopidogrel, as its active ingredients.

Nausea, indigestion, sleeplessness, joint or muscle pain, etc., are a few side effects of Clopidogrel+Atorvastatin. Tell your doctor if they bother you or persist. Seek medical help immediately if you notice unusual bleeding, black stools, blood in urine or unexplained muscle pain or weakness.

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