Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen

• Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen is used to provide symptomatic relief in painful muscle spasms associated with certain musculoskeletal conditions such as gout, arthritis, spondylitis, etc.
• It helps in reducing swelling and inflammation of joints and bones.
• Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen also helps in the quick healing of post-operative wounds, traumas, injuries or sprains.

When should one not use Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen

• If you are allergic to any of the ingredients of Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen.
• If you have severe liver, kidney or heart disease, or an active stomach ulcer.
• If you have a history of allergic reaction to painkillers like ibuprofen, aspirin, etc.
• If you have a history of stomach or intestinal bleeding due to painkillers.
• If you have active bleeding or have a history of bleeding disorder.
• If you are pregnant.
• It is not recommended for children's use.

Common side effects of this drug are:

• Dizziness
• Nausea
• Diarrhoea
• Increased liver enzymes

Other General Warnings

• You experience an allergic reaction like itching, swelling, breathlessness, etc after taking this medicine.
• You have any kind of pre-existing medical conditions like liver or kidney related problems, blood clotting issues, high blood pressure, diabetes, breathing problem, high cholesterol, etc.
• You do not feel any improvement and feel persistent symptoms.
• You are already taking medicines containing paracetamol or diclofenac.
• You have a liver or kidney disorder and taking diuretics, as this medicine can increase the risk of kidney failure. Regular monitoring of kidney function is advised.
• You have Systemic lupus erythematosus (an autoimmune disorder).
• You experience skin reactions like rashes or lesions after taking this medicine.
• You are taking painkillers for a long duration and should keep a check on liver and kidney functions.
• It may increase the chances of adverse effects like the stomach or intestinal bleeding etc. in elderly individuals.

How Does It Work?

• Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen works by the combined action of its three components.
• Diclofenac and paracetamol act by blocking the synthesis of certain chemicals in the body like prostaglandins, that are responsible for causing pain, swelling and inflammation thus offer anti-inflammatory properties.
• Trypsin chymotrypsin is a combination of enzymes that helps in the proper digestion and absorption of required protein in the stomach. They increase the blood circulation in the affected area, improves swelling, pain and quick recovery of the wound.

Interactions with other medicines

• Sometimes other medicines can interfere with the action of Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen if taken at the same time. Always inform your doctor about all the medicine you are taking, which includes all prescribed or non-prescribed herbal medicines, dietary supplements as well as other treatments if you are taking for any disorder.
• In particular, if you are taking anti-sickness medicines like domperidone, other painkillers, immunosuppressants like ciclosporin & tacrolimus, medicines for heart and brain-related disorders like digoxin or lithium respectively, antidiabetic medicines etc.
• Concomitant use of Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen along with anticoagulants like clopidogrel, warfarin and heparin should be avoided as it can increase the risk of bleeding.
• Simultaneous use of Chymotrypsin-Trypsin+Diclofenac+Paracetamol / Acetaminophen along with certain antibiotics like ciprofloxacin and chloramphenicol may increase the risk of severe side effects (nausea, vomiting, stomach upset, diarrhoea etc.).
• Other medicines that should be used with caution are steroids, oral contraceptives etc.

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