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Carbimazole

Molecule Description

Carbimazole belongs to an assortment of medicines called anti-thyroid.

Uses of Carbimazole

It is used to treat hyperactive thyroid gland in adults and children.

Contraindications of Carbimazole

When should one not use Carbimazole

  • Allergy to Carbimazole
  • Allergy to thyroid medicines like Propylthiouracil
  • If you have severe liver disease or blood disorder

Side effects of Carbimazole

Common side effects of this drug are:

  • Allergic reaction like- fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, throat, running or stuffy nose, sneezing
  • Some infections may occur while you are on this medicine
  • Bleeding from unusual parts
  • Headache
  • Feeling dizziness
  • Joint pain (polyarthritis)
  • Muscle pain
  • Stomach upset
  • Change of taste in mouth
  • Thinning of hair
  • Skin rash
  • Itching
  • Neutropenia (low neutrophil count)
  • Leucopenia (low white blood cell count)
  • Agranulocytosis
  • Nerve pain
  • Liver problems- nausea, vomiting, upper stomach pain, yellowing of skin or eyes, skin itching, loss of appetite, clay-colored stools, dark urine, etc.

Precautions and Warnings of Carbimazole

Pregnancy

Q:
Can I take Carbimazole during pregnancy?
A:
You should avoid Carbimazole if you are pregnant or planning pregnancy or breastfeeding. Carbimazole may cross the placenta and harm the unborn baby.

Breast Feeding

Q:
Can I take Carbimazole while breastfeeding?
A:
  • This medicine can pass into the breast milk and can harm the child
  • Do not breastfeed if you are on a medication of Carbimazole

Driving

Q:
Can I drive if I have consumed Carbimazole?
A:
Avoid driving or hazardous activities while on this medicine, as it may cause extreme drowsiness.

Alcohol

Q:
Can I consume alcohol with Carbimazole?
A:
No interactions with alcohol has been reported.

Other General Warnings

Talk to your doctor if
  • You are lactose intolerant or have any other lactose deficiency
  • You are receiving radio-iodine (for thyroid problems)
  • You have mild or moderate liver problems, swelling on neck
  • You have bone marrow depression
  • You have a severe blood disorder

Mode of Action of Carbimazole

How Does It Work?

Carbimazole is chemically a Thioamide. It helps in decreasing the production of a hormone produced by the thyroid gland known as Thyroxine. Carbimazole blocks the synthesis of Thyroxine (T4) and Triiodothyronine (T3).
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Interactions of Carbimazole

Interactions with other medicines

  • Blood thinners (e.g., Warfarin)
  • Steroid medicine- Prednisolone
  • Theophylline
  • Erythromycin antibiotic
  • Heart failure medicines like Digoxin, Digitalis
  • High blood pressure medicines like beta-blockers - Propranolol, Atenolol, etc

Interactions with food items

No interactions with food have been in report. Similarly, there have not been any specific reports for adverse interactions with alcohol or tobacco.

Dietary Restrictions of Carbimazole

No information is available on dietary restrictions while you are takingCarbimazole, consult your doctor or pharmacist for further information.

Dosage of Carbimazole

Overdose

Overdose symptoms may include nausea, vomiting and headache. In the case of an overdose, seek emergency medical attention.

Missed a Dose

Take medicine as soon as you remember. If the missed dose falls at the time of your next scheduled dose, then skip it. Do not take an extra dose to compensate for it.

Frequently Asked Questions (FAQs)

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Q: What should I discuss with my healthcare provider before taking Carbimazole?

  • You must inform your doctor if:
  • You are suffering from any blood or liver diseases or goitre
  • Allergic to Carbimazole or any antithyroid medicine like Propylthiouracil
  • Have lactose deficiency or galalactose intolerance or malabsorption
  • Discuss the risk involved if you fall into the elderly age category or if you are scheduled for any surgery. Inform your doctor if you are taking any other medicines, supplements, or herbs

Q: When and how to consume the medicine?

  • You must take the medicine precisely the way it is prescribed by the physician
  • Follow the instructions mentioned on the prescription label
  • Do not alter the dose unless recommended by your doctor. Do not take it longer than advised
  • Take medicine orally. Swallow it with a glass of water with or without food at the same time daily
  • Do not stop the medication unless advised by your doctor even if you feel better
Last Updated on: 05 Oct 2020 | 10:47 PM (IST)

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Disclaimer
The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts. Please click here for detailed T&C.
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