Amphotericin B
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Molecule Summary
| Uses | Serious Fungal Infections, Kala-Azar |
| Therapy | Anti-Fungal |
| Side Effects | Headache, Nausea, Vomiting, Rash, Chills |
Assurance
available
Regulated
Molecule Description
Amphotericin B is an antifungal medicine. It is used for the treatment of serious fungal infections, kala-azar, and fungal infections of the skin. Amphotericin works by slowing down the growth of fungus and helps in preventing the spread of infection. It comes as an injection, gel, and drops.
Uses
- Serious fungal infections
- Kala azar (visceral leishmaniasis)
- Fungal infection of skin
Contraindications
When should one not use Amphotericin B
Known allergy to amphotericin B.
Side effects
Common side effects of this drug are:
- Headache
- Vomiting
- Nausea
- Fever
- Chills
- Rashes
- Itching
- Decrease in serum potassium levels
- Pain or swelling at the injection site
Precautions and Warnings
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
Talk to your doctor if
- You have a liver or kidney-related disorder.
- You experience skin allergy and rashes after taking this medicine.
- Amphotericin B must not be used for superficial fungal infections.
- When on treatment with amphotericin B, your doctor may ask you to perform blood tests to monitor your potassium, magnesium levels and kidney function.
Mode of Action
How Does It Work?
Amphotericin B binds to the fungal cells and makes them more porous that leads to the leakage of cell components and fungal cell death.
Interactions
Interactions with other medicines
Certain medicines can affect the way amphotericin B works or amphotericin B itself can alter the action of other medicines taken at the same time. Hence, it is important to inform your doctor about all the medications you are currently taking or might take to avoid any possible interaction.
Frequently Asked Questions (FAQs)
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