Allopurinol

• Allopurinol is used to treat chronic gout (increased uric acid quantity in the body), uric acid kidney stones.
• In some types of cancer when there is an increase in uric acid (Tumor Lysis syndrome) caused by anticancer medicines.

When should one not use Allopurinol

Common side effects of this drug are:

• Side effects of Allopurinol may include nausea, diarrhea, joint pain, headache, skin rash, increased liver enzymes or thyroid hormone, depression.
• Severe skin disorders like rash can involve ulcers of the mouth, throat, nose, genitals, and red eyes. Along with this fever, headache, and skin blistering may occur, stop taking Allopurinol and contact your doctor immediately.

Other General Warnings

• You have kidney or liver problems
• You suffer from high blood pressure or have heart problems
• You take medicines like Diuretics or ACE-inhibitors
• You have thyroid problems
• Take special care, just in case you have kidney stones, the kidney stones may become smaller and may enter your urinary tract, drink lots of water

How Does It Work?

Interactions with other medicines

• Theophylline
• Azathioprine and 6-Mercaptopurine
• Cyclosporin
• Warfarin (reported rarely, but is dangerous when it occurs)
• Vidarabine
• Chlorpropamide ( used to treat diabetes)
• Phenytoin
• Cyclophosphamide, Doxorubicin, Bleomycin, Procarbazine, Mechlorethamine
• Aspirin
• Furosemide
• Ampicillin and Amoxicillin
• Diuretics, in particular, Thiazides, especially in renal impairment
• Angiotensin-Converting-Enzyme inhibitors (ACE- inhibitors like Captopril)

Interactions with food items

Overdose

Missed a Dose