Pantosec Dsr Strip Of 15 Capsules
15 Capsule(s) in StripProduct Summary
Pantosec DSR Capsule is a proton pump inhibitor and prokinetic combination used to treat acid reflux not adequately controlled by pantoprazole alone. Cipla GX combines pantoprazole 40 mg, which lowers stomach acid, with domperidone 30 mg, which improves stomach movement and reduces the backward flow of acid.
Medically Reviewed by Dr. Avinav Gupta
Last updated on: 22 October 2026 | 2:13 PM (IST)
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General Information
| Therapy | Antacid and anti-emetic |
| Composition | Pantoprazole(40.0 Mg)+Domperidone(30.0 Mg) Pantoprazole 40.0 Mg+Domperidone 30.0 Mg |
Pantoprazole 40.0 Mg+Domperidone 30.0 Mg

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*Offer applicable on orders above ₹1000About Pantosec
Pantosec DSR Capsule is a combination medicine prescribed for acid reflux and the symptoms that go with it. It contains two active ingredients: pantoprazole, which reduces excess acid in the stomach, and domperidone, which helps control nausea and prevents food and acid from moving back into the food pipe. It is used when treatment with pantoprazole on its own has not controlled the problem. Your doctor will have tried pantoprazole first. This medicine should be taken exactly as prescribed by your doctor. The usual recommendation is to take it once daily, preferably in the morning on an empty stomach or at least one hour before a meal. Taking it at the same time every day ensures better results and reduces stomach-related side effects. Never self-medicate or stop the medicine suddenly without your doctor's advice, as this can cause your symptoms to return or worsen. The domperidone in this medicine can affect the heart's rhythm. Tell your doctor if you have any heart condition, an irregular heartbeat, or a problem with your salt or potassium levels, and tell them about every other medicine you take. Some medicines must not be combined with domperidone. Take it at the lowest dose that controls your symptoms, and for the shortest period. Go back to your doctor for a review rather than continuing it indefinitely. Stop the medicine and get medical help straight away if you develop palpitations, a fast or irregular heartbeat, fainting, or dizziness that comes on suddenly. Some symptoms mean indigestion should be investigated rather than treated. See your doctor promptly if you have unintended weight loss, difficulty or pain on swallowing, persistent vomiting, vomiting blood or material like coffee grounds, black tarry stools, or a family history of stomach cancer. Reducing acid can settle the symptoms while the cause continues. Long-term use of a proton pump inhibitor also has consequences: reduced absorption of vitamin B12, magnesium and calcium, a higher risk of bone fracture, and a higher risk of certain gut infections. Your doctor may check your magnesium level if you take it for a long period. Along with taking Pantosec DSR, making a few lifestyle changes can improve your digestive health. Eating smaller meals, chewing food properly, and avoiding overeating can prevent excess acid formation. It is also advisable not to lie down immediately after eating, as this increases the risk of acid reflux. Limiting spicy, oily, and processed foods, as well as reducing caffeine and carbonated drinks, can further help in controlling acidity. Healthy lifestyle habits are key to long-term relief. Try to quit smoking, reduce alcohol consumption, maintain a healthy body weight, and stay active with regular exercise. Always consult your doctor if your symptoms continue or worsen despite taking Pantosec DSR, so the treatment can be adjusted as needed. Several other brands contain the same two ingredients. Take only the one your doctor prescribed.
Uses
Contraindications
- If you are allergic to pantoprazole, domperidone, or any of the ingredients of Pantosec DSR Capsule.
- If you are taking any product containing rilpivirine.
- If you have stomach or intestinal bleeding or obstruction.
- If you are suffering from a liver or kidney disorder.
- If you have any tumour of the pituitary gland (prolactin pituitary tumours).
- If you have serious heart problems like congestive heart failure, heart rhythm problems or electrolyte imbalance.
- If you are taking any other medicine that can affect the heart rhythm. Ask your doctor if you are not sure.
- In children below 12 years of age.
Side effects
- Headache
- Dry mouth
- Nausea or vomiting
- Stomach pain
- Diarrhoea or constipation
- Wind and bloating
- Dizziness or tiredness
- Difficulty sleeping, or drowsiness
- Rash or itching
- Breast tenderness or swelling, or milk discharge from the breast
- Changes in periods
- Restlessness, or unusual movements of the face or limbs
- Reduced absorption of vitamin B12, magnesium and calcium, which can cause tiredness, pins and needles, muscle cramps or weakness
- An increased risk of bone fracture
- An increased risk of certain gut infections
- Seek medical help: PALPITATIONS, A FAST OR IRREGULAR HEARTBEAT, FAINTING, or sudden dizziness. These relate to the domperidone and need urgent assessment
- Seek medical help: Severe, persistent or watery diarrhoea, especially with fever or stomach cramps, which may indicate a gut infection
- Seek medical help: Muscle cramps or spasms, or seizures, which can be signs of a low magnesium level
- Seek medical help: A severe allergic reaction: swelling of the face, lips, tongue or throat, difficulty breathing, a widespread rash, or collapse
- Seek medical help: A severe skin reaction with blistering or peeling, particularly after sun exposure
- Seek medical help: Yellowing of the skin or eyes, or dark urine
- Seek medical help: A marked reduction in the amount of urine passed, or swelling of the legs
Precautions and Warnings
Alcohol
WITH CAUTIONWith Caution There are no interactions reported between this capsule and alcohol. However, alcohol is known to increase acidity and can make your acidity worse.
Pregnancy
WITH CAUTIONContraindicated The components of this medicine might harm your unborn baby. Tell your doctor if you are pregnant, think you may be pregnant or are planning a pregnancy. Heartburn is common in pregnancy and there are treatments better established for it; your doctor will advise.
Breastfeeding
WITH CAUTIONUnsafe This medicine passes into breast milk in small amounts and might affect your baby.
Driving
WITH CAUTIONWith Caution If you experience headache, dizziness, drowsiness and visual disturbances, it is advisable not to drive or use machines.
Other General Warnings
- You develop watery diarrhoea or fever after taking this medicine.
- You experience black stools.
- You have a stomach tumour or cancer.
- You have a history of fractures or have osteoporosis or are taking steroids.
- On exposure to the sun, you get a rash on your skin. Stop your treatment and inform your doctor as soon as you can.
- You are on this medicine for a long time. Your blood magnesium levels may drop, and your doctor may perform regular tests for the same.
- Taking this medicine for more than one year may increase the chances of developing bone fractures.
- You have serious heart problems like congestive heart failure, heart rhythm problems and electrolyte imbalance.
- You have liver and kidney disease or kidney failure.
- You are taking medicines to treat an infection, or you have HIV.
- You need to go through a regular checkup if you have been taking this medicine for the last year.
- You have any heart condition, an irregular heartbeat, or a problem with your salt or potassium levels.
- You take any medicine that can affect heart rhythm, or you are not sure whether one of your medicines does.
- You develop palpitations, a fast or irregular heartbeat, fainting or sudden dizziness. Stop the medicine and seek help.
- You have unintended weight loss, difficulty swallowing, persistent vomiting, or blood in your vomit or stools.
- You are due to have a test for the stomach bacterium Helicobacter pylori or an endoscopy, as this medicine can affect the result.
Directions for use
- It should be taken as a whole with a sufficient amount of water, preferably in the morning before food.
- Take it about an hour before a meal. Swallow the capsule whole - do not chew or crush it, as it is a sustained-release form.
- Take it at the same time each day, and for the period your doctor set.
- Do not continue beyond the agreed period without a review, because of the domperidone in it.
- Do not stop a long course abruptly without advice, as acid symptoms can rebound.
- Tell your doctor if you take any medicine for the heart, for HIV, an antifungal, an antibiotic, or a blood thinner.
Storage and disposal
- Store this medicine below 25 degrees C.
- Protect it from light.
- Keep it out of the reach of children.
- Keep the capsules in the original strip until you take them. Do not use them after the expiry date, and return unused medicine to a pharmacy.
Quick tips
- You can make certain lifestyle modifications like preventing excess intake of foods that cause acidity, like carbonated drinks and oily or fried food, regular exercise and maintaining a healthy weight.
- It is also advised to limit alcohol intake and quit smoking for better treatment of your acid reflux.
- The use of Pantosec DSR capsule may lead to dry mouth, which is caused by domperidone. If you experience this side effect, drinking plenty of water is recommended.
- If you get a rash on your skin after exposure to the sun, stop the treatment and inform the doctor as soon as possible.
- If you are on long-term treatment with the medicine, it decreases the magnesium levels or causes weakening of bones. Check with the doctor if you may need some supplements for these.
- Take it before food, as your doctor directs. Taking it after food reduces how well it works.
- Ask your doctor to review this medicine rather than continuing it indefinitely. The domperidone in it is meant for short-term use.
- Tell your doctor about any heart condition or irregular heartbeat before starting, and about every other medicine you take.
- Stop and get help for palpitations, a fast or irregular heartbeat, fainting or sudden dizziness.
- See your doctor promptly for weight loss, difficulty swallowing, persistent vomiting, vomiting blood, or black stools. These need investigating.
- Raising the head of the bed and not eating within three hours of lying down help reflux as much as the medicine does.
- Do not stop a long course abruptly; acid symptoms can rebound temporarily.
Dosage
Overdose
Missed a dose
How Pantosec works
Interactions
Interactions with other medicines
- Tell your doctor about every medicine you take. The interactions fall into two groups, and it helps to know which is which.
- Medicines that affect the heart rhythm, because of the domperidone
- Do not take this medicine with others that can affect heart rhythm. These include some antibiotics such as erythromycin, azithromycin, levofloxacin and clarithromycin; antifungals such as ketoconazole, itraconazole and posaconazole; heart rhythm medicines such as amiodarone and disopyramide; and some medicines for mental health such as citalopram, escitalopram and haloperidol.
- Apomorphine for Parkinson's disease, and diltiazem for blood pressure, also interact. Tell your doctor if you take either.
- If you are not sure whether one of your medicines affects heart rhythm, ask your doctor or pharmacist rather than assuming.
- Medicines affected by the reduction in stomach acid
- HIV medicines such as atazanavir, nelfinavir, indinavir and rilpivirine: reducing stomach acid can lower their absorption so much that treatment fails. Some must not be taken with this medicine at all.
- Antifungals such as itraconazole need an acidic stomach to dissolve, so less gets into your system and the treatment may not work.
- Clopidogrel, a blood thinner: a proton pump inhibitor can reduce how well it prevents clots. Tell your doctor.
- Warfarin, methotrexate and digoxin can all be affected. Your doctor may monitor your blood tests or adjust the dose.
- Iron and vitamin B12 are absorbed less well, which matters most with long-term use.
Food interactions
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References
- CDSCO [Internet]. Cdscoonline.gov.in. 2022 [cited 06 December 2022]
- Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006-. Domperidone. [Updated 2024 Oct 15]. [Accessed 26 Dec. 2024].
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3151, Domperidone. Retrieved December 26, 2024
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 4679, Pantoprazole. Retrieved December 26, 2024
- PROTONIX (pantoprazole sodium) - accessdata.fda.gov.(Accessed: 26 December 2024).
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