Deriphyllin Retard 300 Tablet
30 Tablet(s) in Strip
Product Summary
Deriphyllin Retard 300 Tablet is a methylxanthine bronchodilator combination used to treat asthma and chronic obstructive pulmonary disease. It contains etofylline 231 mg and theophylline 69 mg in a prolonged-release tablet manufactured by Zydus Healthcare. The medicines relax airway muscles, widening the airways and making breathing easier.
Medically Reviewed by Dr. Ritu Budania
Last updated on: 13 October 2026 | 4:34 PM (IST)
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ZYDUS HEALTHCARE LIMITED
Dose Form
TABLET
Expiry
General Information
| Therapy | Drugs for chronic obstructive pulmonary disease, anti-asthmatic |
| Composition | Etofylline(231.0 Mg)+Theophylline(69.0 Mg) Etofylline 231.0 Mg+Theophylline 69.0 Mg |
Etofylline 231.0 Mg+Theophylline 69.0 Mg
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*Offer applicable on orders above ₹1000About Deriphyllin
Deriphyllin Retard 300 tablet is used to treat asthma and chronic obstructive pulmonary disease (COPD). It is a condition where the airway is narrowed or swollen with mucous, which leads to breathing difficulties and coughing. It contains Etofylline and Theophylline as active ingredients, known as bronchodilator medicine. This medicine works by relaxing the airway muscles and cleaning the obstruction. This medicine should be taken for the exact dose and duration as your doctor prescribes. You can take this medicine with or without food, but it is better to take it at the same time every day for optimal benefit. Before using the Deriphyllin Retard 300 tablet, inform the doctor if you are pregnant, planning a pregnancy or breastfeeding and about your detailed medical history.
Uses
Contraindications
- If you are allergic to Theophylline, Etofylline or any other ingredients of Deriphyllin Retard 300 tablet.
- If you have a rare blood disorder called Porphyria.
- If this tablet is given along with other medicines like Ephedrine to treat asthma to children less than 6 years of age.
- Deriphyllin Retard 300 tablet is contraindicated in children under 6 months of age.
Side effects
- Vomiting
- Diarrhoea
- Nausea
- Abdominal pain
- Dizziness
- Headache
- Increased urination
- Sleeplessness
Precautions and Warnings
Alcohol
UNSAFEAlcohol can alter the way this medicine works. So, it should be avoided while taking this medicine.
Pregnancy
UNSAFEDeriphyllin Retard 300 tablet is not recommended during pregnancy as there is limited information about its safety in pregnant women. You should consult your doctor if you are pregnant or think you may be planning for a baby before starting this medicine.
Breastfeeding
WITH CAUTIONThe components of the Deriphyllin Retard 300 tablet pass into human milk, which may affect the breastfed baby. Use this medicine under a doctor's supervision.
Driving
WITH CAUTIONSince this medicine may cause dizziness, you should avoid driving if you do not feel well or alert.
Other General Warnings
- You have an underlying medical condition such as heart problems, including high blood pressure, stomach ulcers, or a thyroid problem, liver or kidney diseases, etc.
- You have any liver problems or stomach ulcers or thyroid problems.
- You have any viral infections.
- You have a history of fits or seizures.
- You have prostate-related issues (especially in aged males).
- It should not be used in children below 6 months of age.
- You are a smoker or have a habit of drinking alcohol, which may alter the way this medicine works.
Directions for use
- Take this medicine as a whole with water, with or without eating a meal.
- You should take this medicine regularly at the same time without fail, as directed by your doctor.
- You should not consume it more than the prescribed quantity.
- Do not discontinue the medicine on your own.
Storage and disposal
- Store Deriphyllin Retard 300 tablets at room temperature, away from moisture, sunlight and heat.
- Keep the medicine out of reach of children and pets.
Dosage
Overdose
Missed a dose
How Deriphyllin works
- Deriphyllin Retard 300 tablet contains theophylline and etofylline and they are known as bronchodilators.
- Etofylline is a derivative of theophylline. It works by dilating and relaxing the airway muscles.
- Theophylline decreases swelling in the lungs of asthma patients and helps to relieve the feeling of blockage.
Interactions
Interactions with other medicines
- Some medicines can affect the way Deriphyllin Retard 300 tablet or Deriphyllin itself can reduce the effectiveness of other medicines taken at the same time.
- Tell your doctor about all the medicines, supplements or herbals you are currently taking or might take to avoid any possible interactions.
- Especially, if you are taking medicines to treat high blood pressure, heart failure, high/abnormal cholesterol levels, blood thinners, anti-infectives, anti-diabetics, anti-asthmatics, pain killers, immunomodulatory medicines or medicines for brain-related disorders.
- The use of anaesthetics like halothane with this medicine can result in irregular heartbeats.
- Anticancer medicines such as lomustine, when used with the Deriphyllin tablet may lead to decreased platelets.
- Deriphyllin Retard 300 tablet, when used together with steroids and water pills, may result in decreased potassium levels.
- The use of any other medicines containing theophylline or derivatives of theophylline may result in increased side effects.
Food interactions
Frequently asked questions
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References
- Uniphyllin Continus 200 mg prolonged release tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 11 April 2022]
- Uniphyllin Continus 200 mg prolonged release tablets - Patient Information Leaflet (PIL) - (emc) [Internet]. Medicines.org.uk. 2021 [cited 11 April 2022]
- Etofylline nicotinate: Uses, Interactions, Mechanism of Action | DrugBank Online [Internet]. Go.drugbank.com. 2021 [cited 11 April 2022]
- CDSCO [Internet]. Cdscoonline.gov.in. 2021 [cited 11 April 2022]
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 1892, Etofylline. Retrieved January 8, 2025
- Jilani TN, Preuss CV, Sharma S. Theophylline. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. [Cited 2025 Jan 8].
- National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 2153, Theophylline. Retrieved January 8, 2025
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