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Zolsoma 5mg Tablet

10 Tablet(s) in Strip
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Zolsoma 5mg Tablet Description

Zolsoma 5 mg Tablet is a prescription medicine used in the treatment of insomnia. It helps to synchronize the body’s biological day-night rhythm known as circadian rhythm. Insomnia is a sleep disorde

r that causes difficulty in falling asleep or staying asleep. Zolsoma 5 mg Tablet is a combination medicine that contains zolpidem and melatonin as the active ingredient. It is a sedative-hypnotic combination of medicine. Zolpidem works by increasing the activity chemical messenger in the brain called Gamma-aminobutyric acid (GABA), which act as a natural nerve-calming agent, thereby inducing sleep. Melatonin is a natural hormone produced by the brain in response to darkness that helps to maintain the normal sleep cycle. Thus, these two-combination of medicine helps to fall asleep and treat insomnia. Zolsoma 5 mg Tablet should be taken as advised by your doctor. There are many side effects associated with this medicine, so it is advised to take it after the doctor’s consultation and it must be carefully monitored. Do not stop taking this medicine suddenly without consulting your doctor, as it can cause clinical worsening of your condition or may lead to withdrawal symptoms.


Product Summary

Offer Price₹51.00
You Save₹9.00 (15% on MRP)
ContainsMelatonin(3.0 Mg) + Zolpidem(5.0 Mg)
UsesTreatment of Insomnia
Side effectsNausea, Diarrhoea, Dry mouth, Headache, Dizziness, Drowsiness
Check more medicines with composition as Melatonin(3.0 Mg) + Zolpidem(5.0 Mg)

Uses of Zolsoma 5mg Tablet

  • As per CDSCO-
  • Treatment of Insomnia

Contraindications of Zolsoma 5mg Tablet

  • If you are allergic to any component of the Zolsoma Tablet
  • If you are experiencing sudden mood changes or suicidal ideation
  • If you have myasthenia gravis (a disease that causes muscle weakness)
  • If you have liver impairment
  • If you have kidney problems
  • If you have any history of drug or alcohol addiction
  • If you have any mental health problems
  • If you have respiratory problems like sleep apnea

Side effects of Zolsoma 5mg Tablet

  • Nausea
  • Diarrhoea
  • Dry mouth
  • Headache
  • Dizziness
  • Drowsiness

Precautions and Warnings of Zolsoma 5mg Tablet



Can I take Zolsoma Tablet during pregnancy?
No, Zolsoma Tablets are unsafe during pregnancy. Some research studies have shown a definite risk to the developing unborn baby. Sometimes your doctor may prescribe this medicine during severe conditions if they think the benefits outweigh the risks. Do not take it without consulting your doctor.

Breast Feeding

Can I take Zolsoma Tablet while breastfeeding?
Zolsoma Tablets can be unsafe during breastfeeding as it may get excreted into breast milk and can affect the baby. Consult your doctor and discuss the potential risks and benefits of this medicine. Your doctor may advise you to discontinue breastfeeding or prescribe low doses if you continue breastfeeding.


Can I drive if I have taken Zolsoma Tablet?
Zolsoma Tablet may cause side effects that could affect your ability to drive. The medicine may decrease alertness, affect your vision and can cause dizziness, lightheadedness. Avoid driving if you are experiencing the side effects mentioned above after taking this medicine.


Can I consume alcohol with the Zolsoma Tablet?
No, do not consume alcohol with Zolsoma Tablet, as it increases the severity of side effects like dizziness, drowsiness, lethargy, blurred vision, liver injury, etc. It also worsens the symptoms for which you are taking this medicine.

Other General Warnings

Talk to your doctor if
  • You have any allergic reactions after taking Zolsoma Tablet.
  • You have any suicidal ideation or self-harming thoughts
  • You experience any severe side effects
  • Your symptoms do not improve or there is worsening of your condition
  • You have a history of epilepsy or fits and are taking antiepileptic medication
  • You have withdrawal symptoms like agitation, nausea, tremor, sweating and confusion

Mode of Action of Zolsoma 5mg Tablet

How Does It Work?

Zolsoma 5 mg Tablet is a combination medicine that contains Zolpidem-5 mg and Melatonin-3 mg as the active ingredients. It is a sedative-hypnotic combination of medicine. Zolpidem works by increasing ...
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Directions for Use of Zolsoma 5mg Tablet

  • Take Zolsoma Tablet exactly as prescribed by the doctor
  • Take this medication on a regular schedule preferably at the same time every day
  • Take the Tablet as a whole with a full glass of water. Do not break/crush the tablet or chew this medicine
  • You can take the Zolsoma Tablet before or after consuming food or as prescribed by your doctor
  • Do not exceed the recommended dosage as it can lead to overdose
  • Do not stop using it abruptly, as it may lead to withdrawal symptoms
  • Do not take if the package has been broken or opened

Interactions of Zolsoma 5mg Tablet

Interactions with other medicines

  • Tell your doctor and pharmacist what prescription and non-prescription medications, herbal products, vitamins and nutritional supplements, you are consuming or plan to take as there is a chance of dru...
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  • Interaction with antidepressants or mood-elevating medicines like fluoxetine and desipramine can cause increased side effects
  • Interaction with antihistamines (allergy medicines), opioid painkillers, sleeping pills, etc, can increase drowsiness and fatigue
  • Interaction with antifungal medications like itraconazole and ketoconazole can reduce the effects of it.

Interactions with food items

  • You should avoid caffeine-containing drinks like cola, tea, coffee etc, especially in the evening

Storage and disposal of Zolsoma 5mg Tablet

Store Zolsoma Tablet at room temperature in a cool and dry area, away from sunlight. Keep the medication away from children and pet animals in a closed or locked cabinet. Do not remove the medicine fr...
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Dosage of Zolsoma 5mg Tablet


Zolsoma Tablet overdose can cause symptoms like drowsiness, problems with coordination, confusion, difficulty speaking, slowed breathing or heartbeat and loss of consciousness. If you overdose on this...
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Missed a Dose

Missed doses of Zolsoma Tablet should be taken right away unless it is almost time for the next dose. In that case, you should skip the forgotten dose (rather than taking a double dose) and take the n...
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Content Details


Dr. Zishan Ahmad

Final year MBBS Student


Dr. Varsha Parihar

MBBS, MD (Community Medicine)

Frequently Asked Questions (FAQs)


Q: Can I get addicted to Zolsoma Tablet?

A: If you take Zolsoma Tablet for a few weeks, you're unlikely to become addicted to this medicine. However, if you are taking it for longer than 4 weeks then you may get dependent on it. It's better to consult your doctor if you have any queries regarding this issue.

Q: Can I Stop taking the Zolsoma Tablet on my own after the desired effect?

A: No, Do not stop taking Zolsoma Tablet despite having improvement in your condition . Continue the medicine as prescribed by your doctor; otherwise, it may lead to withdrawal symptoms. Talk to your doctor before stopping the medicine as doses need to be slowly tapered to avoid undesirable side effects.

Q: Does taking Zolsoma Tablet more than the recommended dose will resolve my symptoms quickly?

A: No, do not take Zolsoma Tablet more than the recommended dose as it may lead to overdose or may worsen your condition. Consult your doctor if you have any queries about the doses and do not increase the dose on your own.
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Last Updated on: 28 Feb 2022 | 09:37 AM (IST)

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